General information for g2238.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Tight junction protein ZO-1.
Parent gene
- The parent gene g2238 is located on chr_3: 16232632..16240845 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2238 | g2238.t1 | isoform | g2238.t1 | 16232632 | 16240845 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon1 | 16232632 | 16232855 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS1 | 16232632 | 16232855 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon2 | 16233172 | 16234937 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS2 | 16233172 | 16234937 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon3 | 16237563 | 16237671 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS3 | 16237563 | 16237671 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon4 | 16238572 | 16238854 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS4 | 16238572 | 16238854 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon5 | 16238920 | 16239112 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS5 | 16238920 | 16239112 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon6 | 16239524 | 16240223 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS6 | 16239524 | 16240223 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon7 | 16240277 | 16240424 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS7 | 16240277 | 16240424 |
| chr_3 | g2238 | g2238.t1 | exon | g2238.t1.exon8 | 16240645 | 16240845 |
| chr_3 | g2238 | g2238.t1 | cds | g2238.t1.CDS8 | 16240645 | 16240845 |
| chr_3 | g2238 | g2238.t1 | TSS | g2238.t1 | NA | NA |
| chr_3 | g2238 | g2238.t1 | TTS | g2238.t1 | NA | NA |
Sequences
>g2238.t1 Gene=g2238 Length=3624
ATGAACACCACATCCCGTTTATCCTATGCATCGAGTCCCGAGTCAGATTTGGAATTGAGT
CCAGGCCCATCTGCATCGTTATCATTGGGCAATTTACCGCAACTTGTAAAATCGAGCTCT
GATCCATCAATTGCTACCAATCAAGATAATCTCGATCGTGATCGTGAAGAAATGGTTGAA
GGAATGCCACCACCTTATACGACACCTTATGATCATTCAACTGCTCATACTAGACGATTG
ACAGTTGACAATAAATACGGTTTTTCACCATCACAACAACAGCAGCCAACTGATGAACAA
GCTCTCTATGGAACACGTCCAACTAATACAAATGGCATTTATGGTCAAAACGTACCAGAT
TTGCCACCAAGAATAGACAGAACATCAAAACCAAGTTCAAGTACACCAGGTTCATCATTG
CCATCAAGAACTTCATCGTCAGTTAATAGCAATGGTGGAACTTTAGGAAGATCAGCACAA
GAGCGACTTTTTGGAAGTGCTCAAAAACAAGCGTTGAGTCCTGATGATCAACAAGATGAC
CTTTATACAGCATCGAATAAACTTCTTAATACACTCGAACCCAAAAAGATGGGTAATGAA
GATTCATTAGAAAGAAGAAATATTCATCATCACCATCATCATCATTCAAATGCTCAGAAT
TCTTTAGATCGAACGAATTCAACACAGAAAAATGGATCGAGTTATGATAGTGTGTCAAGT
TATGATTCTTATAATACAAATCAACCACAACAAGCTGTCACAACTTCAACTTTATCAGTA
CAAAATCGTTTAGGTCCAAATGCACCTGATGATTTAAAATCGATTCCACCACCAACCGTA
AATCGTGCATCAATGGTAAATTCACAAGATTATGCCACAAATCAGCGAAATTCGATGAAC
GACAGCAACTATAGTTACAATAATGGAATGGATCAACATGCACAGCCACGTAATTCAATG
GTTCTCCCACAACGACCAACAAATTTGCTGATCGAAAGTCCAAGAAAACCTCATATGATG
GAAACAAAAACAGATTATGGAAAATATAGTAGAAACAATTCAGCCACTCAAGCCGATTAT
ATTAAGCCACCGAAAATTGCACAAGTTGTTCCTCCGATTCCCAATTCACAACCACCGGTC
AGTAGCGCTTTTAAGCCAGTTCCACCACCAAAGCCCAAGAATTATCGTCCACCGATGCCT
GGAACAAATGGAAATGGAAACGGAAATCAATGGGAAAATGGGGAATCACTTTCACCACGT
TCACCACCAAATGGAATTTATTATTCAACAACTAATAATAATCAACAGCCTCCATCTCAG
CATCAACATTATCATCATCAAAGTATGACAAACGGTTCATCACCGCATTATAGTCATCAT
CAATTTGGAGGCAATGGAAATCATCATTCTAATTATGGTCAGCCACCAATGCCACCGCAA
CATATGCAATCACCACCAATGTTTGGTAATGGCTATAACAATCATCAATATTATGGTAGT
GGAAACTATAGAAATCCTGGATTTGGAAATTTGCCAATTCCATCACAATATGGCATCGAC
TTGACAAATCGAGAGCAGAGAGGTTCTGCCTTTGAGCTTTATCGAAAACCACAAATAGGT
GCACATAACATGAGCGATATGCAACCGCCACCAATATCGAGACAGAATTTGCCACCAAAG
CAGCAGCATCGTTATGATATGGTTAGTGTCACACCTGAGCCACCAGAATTACCAGCGAAA
GCAAAGAAAAATCCATTAAAAAGTCCCCTGAAAGCGATAAAGAAGGCAATTGTTAAAGGC
ACAAATTCATTAAGAAGGCAAGCCAGTTTTATGGACAGCAATAGCGGTGAATCAAAGAAA
GCACGGTCATTAAGGCGGCAACATTCAATGATGGAACGAGGTTCTAATCGAATGTTTTAT
CCACCACCACCTCATCATCAACAAGACTATTATGAATATCAACAGCAACAATACTACAAT
TATTATTATCAACAGCAAAGATATTATCCACAAGATGAACGCTTTGCCTGGTATCAGCGA
CATGAAAGATATTATCCTACAAACATGGCATATGACGATGAACAGCCGTTGTATGGAAAT
TATGGACCACCGCCAGAAGAGAGTATTTATGCTAATCGTGCGCTCATTGAACTCGAAAGG
TCAGCACCAATTCAGACTTCGGGTGGACGAATTGTTCGTCGTCATAGCATGAATGAACGA
CAACGTGAAGTGCCCGCATTTGCAACATTAACTAAGCGACGCTCTAAATATGCTGAAGAT
ATTGACGATAGATTCGCAAACATGTCAATTGAAGAGCCAATTTATCAAAGTCAACGTGGT
TCATTAATGTATCAAGAGCAAATGAAACCTCGACCAATGCCACGACAACAACCTGTCGAA
CGTCCACTAGATGATAATCAAAAATTATTGCAAGCACGTAAGGATATAAATTCACCAGGG
ACTTCTTCAGCATCTACAACTACATCACTATCATCGCCATCAAAAGAACGAAATTTACGA
GATTCACGACGACAATTAAAAGATCAAATCTATCAATCACGTTTAGAAACAATGCAATCA
ATGGCAGAGCCAAATTATTTGACAAGGTCAAGTAGTGGTACAAGTAGTAATGCTGGCAGT
AATTTAAGATCACAGCCAATTTATGAGTCAAAGAAAGAGGCAGAAGAAAGTCATGAAAAT
GAAAATGACAAAACAATGAACTCAAGTACTGAATGTGAAGCATCAAATGAAAATAATGAG
CAAGAAAAGTCACTACTAGAAGTGATTGAGGAGACGCTAATTAAAAATAAGTCACAAGAC
CATCTAAATGAGGTTGATTCGATACCGTTTGTTGATGAAGAAACTCCTGCAGCAAAAAGC
AGTGACACTATAGAAGAAAGTGAAGATTCGCTTCAAAGAACAGCAATTGAGAACACTGTA
ATAACAAAAAAAGAGCCAATTAACATTAATAACATTATCAAACGTGCTGCACCACCACCG
CCGCCAGTTCGTTCACCAACAACCGCAAAAACAACAACAGCTGCCCCGACAGAATCAGTC
TATGAATCACATACGTCTATTGATACACAAGCTAGTCTTCCTACAAGCATTGGTCCGCCT
AATGCACAGTCAACTCCATATGCTAGTGAATTAACGCTCAAAGAACAAAAATCACTCGCA
AAAGCACGATTTTTAGCTGCGCCACCAATTAGAAGTCCAATAACAACTAAAGGATATTTC
GACGAGATGGGTGGAATTTTAGAGGATAATGTTTGGAATGTTTCATTGATAATTCCACCT
GGTGCACTACCAACAGGCCAAAAACAAGAAATTTATTTCACTGTCACAGATCCAAGGATG
TCAGAAGCAGTTGGTGGTCCACCACTTGACATGGAAAATGGTGAAAAAATGCTGTCACCT
CTTGTAATGTGCGGTCCCGTTGGACTTGAGTTTCTTGAACCAGTCACATTGAATATTCCA
CATTGTGCATCAAGCATGCCAAGTCTTGGTTTATCGGTAAAAGCTACTGATAGTGAGAAA
AATTTAACAACCAATTGGGACAACATTGATCTACCACCATCAAACACTGCACATCAAGTC
AGCGTTAAAGTTGATCATTTTTAG
>g2238.t1 Gene=g2238 Length=1207
MNTTSRLSYASSPESDLELSPGPSASLSLGNLPQLVKSSSDPSIATNQDNLDRDREEMVE
GMPPPYTTPYDHSTAHTRRLTVDNKYGFSPSQQQQPTDEQALYGTRPTNTNGIYGQNVPD
LPPRIDRTSKPSSSTPGSSLPSRTSSSVNSNGGTLGRSAQERLFGSAQKQALSPDDQQDD
LYTASNKLLNTLEPKKMGNEDSLERRNIHHHHHHHSNAQNSLDRTNSTQKNGSSYDSVSS
YDSYNTNQPQQAVTTSTLSVQNRLGPNAPDDLKSIPPPTVNRASMVNSQDYATNQRNSMN
DSNYSYNNGMDQHAQPRNSMVLPQRPTNLLIESPRKPHMMETKTDYGKYSRNNSATQADY
IKPPKIAQVVPPIPNSQPPVSSAFKPVPPPKPKNYRPPMPGTNGNGNGNQWENGESLSPR
SPPNGIYYSTTNNNQQPPSQHQHYHHQSMTNGSSPHYSHHQFGGNGNHHSNYGQPPMPPQ
HMQSPPMFGNGYNNHQYYGSGNYRNPGFGNLPIPSQYGIDLTNREQRGSAFELYRKPQIG
AHNMSDMQPPPISRQNLPPKQQHRYDMVSVTPEPPELPAKAKKNPLKSPLKAIKKAIVKG
TNSLRRQASFMDSNSGESKKARSLRRQHSMMERGSNRMFYPPPPHHQQDYYEYQQQQYYN
YYYQQQRYYPQDERFAWYQRHERYYPTNMAYDDEQPLYGNYGPPPEESIYANRALIELER
SAPIQTSGGRIVRRHSMNERQREVPAFATLTKRRSKYAEDIDDRFANMSIEEPIYQSQRG
SLMYQEQMKPRPMPRQQPVERPLDDNQKLLQARKDINSPGTSSASTTTSLSSPSKERNLR
DSRRQLKDQIYQSRLETMQSMAEPNYLTRSSSGTSSNAGSNLRSQPIYESKKEAEESHEN
ENDKTMNSSTECEASNENNEQEKSLLEVIEETLIKNKSQDHLNEVDSIPFVDEETPAAKS
SDTIEESEDSLQRTAIENTVITKKEPININNIIKRAAPPPPPVRSPTTAKTTTAAPTESV
YESHTSIDTQASLPTSIGPPNAQSTPYASELTLKEQKSLAKARFLAAPPIRSPITTKGYF
DEMGGILEDNVWNVSLIIPPGALPTGQKQEIYFTVTDPRMSEAVGGPPLDMENGEKMLSP
LVMCGPVGLEFLEPVTLNIPHCASSMPSLGLSVKATDSEKNLTTNWDNIDLPPSNTAHQV
SVKVDHF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 20 | g2238.t1 | Coils | Coil | Coil | 912 | 932 | - |
| 19 | g2238.t1 | Gene3D | G3DSA:2.60.220.30 | - | 1068 | 1207 | 6.1E-36 |
| 5 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 47 | - |
| 17 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 75 | - |
| 18 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 108 | 153 | - |
| 13 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 127 | 153 | - |
| 14 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 209 | 257 | - |
| 16 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 220 | 257 | - |
| 12 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 434 | 457 | - |
| 6 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 812 | 835 | - |
| 8 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 812 | 843 | - |
| 7 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 855 | 887 | - |
| 11 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 855 | 922 | - |
| 10 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 888 | 906 | - |
| 9 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 995 | 1041 | - |
| 15 | g2238.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1007 | 1041 | - |
| 2 | g2238.t1 | PANTHER | PTHR13865 | TIGHT JUNCTION PROTEIN | 771 | 1193 | 6.1E-56 |
| 3 | g2238.t1 | PANTHER | PTHR13865:SF28 | POLYCHAETOID, ISOFORM O | 771 | 1193 | 6.1E-56 |
| 1 | g2238.t1 | Pfam | PF00791 | ZU5 domain | 1076 | 1176 | 1.9E-24 |
| 21 | g2238.t1 | ProSiteProfiles | PS51145 | ZU5 domain profile. | 1074 | 1207 | 21.084 |
| 4 | g2238.t1 | SMART | SM00218 | zu_1 | 1072 | 1180 | 5.6E-17 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
