General information for g2238.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Tight junction protein ZO-1.
Parent gene
- The parent gene g2238 is located on chr_3: 16232632..16240845 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2238 | g2238.t2 | isoform | g2238.t2 | 16232632 | 16240845 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon1 | 16232632 | 16232855 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS1 | 16232632 | 16232855 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon2 | 16233172 | 16234937 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS2 | 16233172 | 16234937 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon3 | 16237563 | 16237674 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS3 | 16237563 | 16237674 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon4 | 16238572 | 16238854 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS4 | 16238572 | 16238854 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon5 | 16238920 | 16239112 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS5 | 16238920 | 16239112 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon6 | 16239524 | 16240223 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS6 | 16239524 | 16240223 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon7 | 16240277 | 16240424 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS7 | 16240277 | 16240424 |
| chr_3 | g2238 | g2238.t2 | exon | g2238.t2.exon8 | 16240645 | 16240845 |
| chr_3 | g2238 | g2238.t2 | cds | g2238.t2.CDS8 | 16240645 | 16240845 |
| chr_3 | g2238 | g2238.t2 | TSS | g2238.t2 | NA | NA |
| chr_3 | g2238 | g2238.t2 | TTS | g2238.t2 | NA | NA |
Sequences
>g2238.t2 Gene=g2238 Length=3627
ATGAACACCACATCCCGTTTATCCTATGCATCGAGTCCCGAGTCAGATTTGGAATTGAGT
CCAGGCCCATCTGCATCGTTATCATTGGGCAATTTACCGCAACTTGTAAAATCGAGCTCT
GATCCATCAATTGCTACCAATCAAGATAATCTCGATCGTGATCGTGAAGAAATGGTTGAA
GGAATGCCACCACCTTATACGACACCTTATGATCATTCAACTGCTCATACTAGACGATTG
ACAGTTGACAATAAATACGGTTTTTCACCATCACAACAACAGCAGCCAACTGATGAACAA
GCTCTCTATGGAACACGTCCAACTAATACAAATGGCATTTATGGTCAAAACGTACCAGAT
TTGCCACCAAGAATAGACAGAACATCAAAACCAAGTTCAAGTACACCAGGTTCATCATTG
CCATCAAGAACTTCATCGTCAGTTAATAGCAATGGTGGAACTTTAGGAAGATCAGCACAA
GAGCGACTTTTTGGAAGTGCTCAAAAACAAGCGTTGAGTCCTGATGATCAACAAGATGAC
CTTTATACAGCATCGAATAAACTTCTTAATACACTCGAACCCAAAAAGATGGGTAATGAA
GATTCATTAGAAAGAAGAAATATTCATCATCACCATCATCATCATTCAAATGCTCAGAAT
TCTTTAGATCGAACGAATTCAACACAGAAAAATGGATCGAGTTATGATAGTGTGTCAAGT
TATGATTCTTATAATACAAATCAACCACAACAAGCTGTCACAACTTCAACTTTATCAGTA
CAAAATCGTTTAGGTCCAAATGCACCTGATGATTTAAAATCGATTCCACCACCAACCGTA
AATCGTGCATCAATGGTAAATTCACAAGATTATGCCACAAATCAGCGAAATTCGATGAAC
GACAGCAACTATAGTTACAATAATGGAATGGATCAACATGCACAGCCACGTAATTCAATG
GTTCTCCCACAACGACCAACAAATTTGCTGATCGAAAGTCCAAGAAAACCTCATATGATG
GAAACAAAAACAGATTATGGAAAATATAGTAGAAACAATTCAGCCACTCAAGCCGATTAT
ATTAAGCCACCGAAAATTGCACAAGTTGTTCCTCCGATTCCCAATTCACAACCACCGGTC
AGTAGCGCTTTTAAGCCAGTTCCACCACCAAAGCCCAAGAATTATCGTCCACCGATGCCT
GGAACAAATGGAAATGGAAACGGAAATCAATGGGAAAATGGGGAATCACTTTCACCACGT
TCACCACCAAATGGAATTTATTATTCAACAACTAATAATAATCAACAGCCTCCATCTCAG
CATCAACATTATCATCATCAAAGTATGACAAACGGTTCATCACCGCATTATAGTCATCAT
CAATTTGGAGGCAATGGAAATCATCATTCTAATTATGGTCAGCCACCAATGCCACCGCAA
CATATGCAATCACCACCAATGTTTGGTAATGGCTATAACAATCATCAATATTATGGTAGT
GGAAACTATAGAAATCCTGGATTTGCAGGAAATTTGCCAATTCCATCACAATATGGCATC
GACTTGACAAATCGAGAGCAGAGAGGTTCTGCCTTTGAGCTTTATCGAAAACCACAAATA
GGTGCACATAACATGAGCGATATGCAACCGCCACCAATATCGAGACAGAATTTGCCACCA
AAGCAGCAGCATCGTTATGATATGGTTAGTGTCACACCTGAGCCACCAGAATTACCAGCG
AAAGCAAAGAAAAATCCATTAAAAAGTCCCCTGAAAGCGATAAAGAAGGCAATTGTTAAA
GGCACAAATTCATTAAGAAGGCAAGCCAGTTTTATGGACAGCAATAGCGGTGAATCAAAG
AAAGCACGGTCATTAAGGCGGCAACATTCAATGATGGAACGAGGTTCTAATCGAATGTTT
TATCCACCACCACCTCATCATCAACAAGACTATTATGAATATCAACAGCAACAATACTAC
AATTATTATTATCAACAGCAAAGATATTATCCACAAGATGAACGCTTTGCCTGGTATCAG
CGACATGAAAGATATTATCCTACAAACATGGCATATGACGATGAACAGCCGTTGTATGGA
AATTATGGACCACCGCCAGAAGAGAGTATTTATGCTAATCGTGCGCTCATTGAACTCGAA
AGGTCAGCACCAATTCAGACTTCGGGTGGACGAATTGTTCGTCGTCATAGCATGAATGAA
CGACAACGTGAAGTGCCCGCATTTGCAACATTAACTAAGCGACGCTCTAAATATGCTGAA
GATATTGACGATAGATTCGCAAACATGTCAATTGAAGAGCCAATTTATCAAAGTCAACGT
GGTTCATTAATGTATCAAGAGCAAATGAAACCTCGACCAATGCCACGACAACAACCTGTC
GAACGTCCACTAGATGATAATCAAAAATTATTGCAAGCACGTAAGGATATAAATTCACCA
GGGACTTCTTCAGCATCTACAACTACATCACTATCATCGCCATCAAAAGAACGAAATTTA
CGAGATTCACGACGACAATTAAAAGATCAAATCTATCAATCACGTTTAGAAACAATGCAA
TCAATGGCAGAGCCAAATTATTTGACAAGGTCAAGTAGTGGTACAAGTAGTAATGCTGGC
AGTAATTTAAGATCACAGCCAATTTATGAGTCAAAGAAAGAGGCAGAAGAAAGTCATGAA
AATGAAAATGACAAAACAATGAACTCAAGTACTGAATGTGAAGCATCAAATGAAAATAAT
GAGCAAGAAAAGTCACTACTAGAAGTGATTGAGGAGACGCTAATTAAAAATAAGTCACAA
GACCATCTAAATGAGGTTGATTCGATACCGTTTGTTGATGAAGAAACTCCTGCAGCAAAA
AGCAGTGACACTATAGAAGAAAGTGAAGATTCGCTTCAAAGAACAGCAATTGAGAACACT
GTAATAACAAAAAAAGAGCCAATTAACATTAATAACATTATCAAACGTGCTGCACCACCA
CCGCCGCCAGTTCGTTCACCAACAACCGCAAAAACAACAACAGCTGCCCCGACAGAATCA
GTCTATGAATCACATACGTCTATTGATACACAAGCTAGTCTTCCTACAAGCATTGGTCCG
CCTAATGCACAGTCAACTCCATATGCTAGTGAATTAACGCTCAAAGAACAAAAATCACTC
GCAAAAGCACGATTTTTAGCTGCGCCACCAATTAGAAGTCCAATAACAACTAAAGGATAT
TTCGACGAGATGGGTGGAATTTTAGAGGATAATGTTTGGAATGTTTCATTGATAATTCCA
CCTGGTGCACTACCAACAGGCCAAAAACAAGAAATTTATTTCACTGTCACAGATCCAAGG
ATGTCAGAAGCAGTTGGTGGTCCACCACTTGACATGGAAAATGGTGAAAAAATGCTGTCA
CCTCTTGTAATGTGCGGTCCCGTTGGACTTGAGTTTCTTGAACCAGTCACATTGAATATT
CCACATTGTGCATCAAGCATGCCAAGTCTTGGTTTATCGGTAAAAGCTACTGATAGTGAG
AAAAATTTAACAACCAATTGGGACAACATTGATCTACCACCATCAAACACTGCACATCAA
GTCAGCGTTAAAGTTGATCATTTTTAG
>g2238.t2 Gene=g2238 Length=1208
MNTTSRLSYASSPESDLELSPGPSASLSLGNLPQLVKSSSDPSIATNQDNLDRDREEMVE
GMPPPYTTPYDHSTAHTRRLTVDNKYGFSPSQQQQPTDEQALYGTRPTNTNGIYGQNVPD
LPPRIDRTSKPSSSTPGSSLPSRTSSSVNSNGGTLGRSAQERLFGSAQKQALSPDDQQDD
LYTASNKLLNTLEPKKMGNEDSLERRNIHHHHHHHSNAQNSLDRTNSTQKNGSSYDSVSS
YDSYNTNQPQQAVTTSTLSVQNRLGPNAPDDLKSIPPPTVNRASMVNSQDYATNQRNSMN
DSNYSYNNGMDQHAQPRNSMVLPQRPTNLLIESPRKPHMMETKTDYGKYSRNNSATQADY
IKPPKIAQVVPPIPNSQPPVSSAFKPVPPPKPKNYRPPMPGTNGNGNGNQWENGESLSPR
SPPNGIYYSTTNNNQQPPSQHQHYHHQSMTNGSSPHYSHHQFGGNGNHHSNYGQPPMPPQ
HMQSPPMFGNGYNNHQYYGSGNYRNPGFAGNLPIPSQYGIDLTNREQRGSAFELYRKPQI
GAHNMSDMQPPPISRQNLPPKQQHRYDMVSVTPEPPELPAKAKKNPLKSPLKAIKKAIVK
GTNSLRRQASFMDSNSGESKKARSLRRQHSMMERGSNRMFYPPPPHHQQDYYEYQQQQYY
NYYYQQQRYYPQDERFAWYQRHERYYPTNMAYDDEQPLYGNYGPPPEESIYANRALIELE
RSAPIQTSGGRIVRRHSMNERQREVPAFATLTKRRSKYAEDIDDRFANMSIEEPIYQSQR
GSLMYQEQMKPRPMPRQQPVERPLDDNQKLLQARKDINSPGTSSASTTTSLSSPSKERNL
RDSRRQLKDQIYQSRLETMQSMAEPNYLTRSSSGTSSNAGSNLRSQPIYESKKEAEESHE
NENDKTMNSSTECEASNENNEQEKSLLEVIEETLIKNKSQDHLNEVDSIPFVDEETPAAK
SSDTIEESEDSLQRTAIENTVITKKEPININNIIKRAAPPPPPVRSPTTAKTTTAAPTES
VYESHTSIDTQASLPTSIGPPNAQSTPYASELTLKEQKSLAKARFLAAPPIRSPITTKGY
FDEMGGILEDNVWNVSLIIPPGALPTGQKQEIYFTVTDPRMSEAVGGPPLDMENGEKMLS
PLVMCGPVGLEFLEPVTLNIPHCASSMPSLGLSVKATDSEKNLTTNWDNIDLPPSNTAHQ
VSVKVDHF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 20 | g2238.t2 | Coils | Coil | Coil | 913 | 933 | - |
| 19 | g2238.t2 | Gene3D | G3DSA:2.60.220.30 | - | 1069 | 1208 | 6.1E-36 |
| 7 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 47 | - |
| 17 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 75 | - |
| 18 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 108 | 153 | - |
| 11 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 127 | 153 | - |
| 12 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 209 | 257 | - |
| 13 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 220 | 257 | - |
| 10 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 434 | 457 | - |
| 14 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 813 | 844 | - |
| 15 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 813 | 836 | - |
| 8 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 856 | 923 | - |
| 16 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 856 | 888 | - |
| 6 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 889 | 907 | - |
| 5 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 996 | 1042 | - |
| 9 | g2238.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1008 | 1042 | - |
| 2 | g2238.t2 | PANTHER | PTHR13865 | TIGHT JUNCTION PROTEIN | 772 | 1194 | 5.0E-56 |
| 3 | g2238.t2 | PANTHER | PTHR13865:SF28 | POLYCHAETOID, ISOFORM O | 772 | 1194 | 5.0E-56 |
| 1 | g2238.t2 | Pfam | PF00791 | ZU5 domain | 1077 | 1177 | 1.9E-24 |
| 21 | g2238.t2 | ProSiteProfiles | PS51145 | ZU5 domain profile. | 1075 | 1208 | 21.084 |
| 4 | g2238.t2 | SMART | SM00218 | zu_1 | 1073 | 1181 | 5.6E-17 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
