General information for g2265.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Mpv17-like protein 2.
Parent gene
- The parent gene g2265 is located on chr_3: 16345072..16345885 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2265 | g2265.t2 | isoform | g2265.t2 | 16344134 | 16345885 |
| chr_3 | g2265 | g2265.t2 | exon | g2265.t2.exon1 | 16344134 | 16344874 |
| chr_3 | g2265 | g2265.t2 | cds | g2265.t2.CDS1 | 16344842 | 16344874 |
| chr_3 | g2265 | g2265.t2 | exon | g2265.t2.exon2 | 16345117 | 16345195 |
| chr_3 | g2265 | g2265.t2 | cds | g2265.t2.CDS2 | 16345117 | 16345195 |
| chr_3 | g2265 | g2265.t2 | exon | g2265.t2.exon3 | 16345251 | 16345290 |
| chr_3 | g2265 | g2265.t2 | cds | g2265.t2.CDS3 | 16345251 | 16345290 |
| chr_3 | g2265 | g2265.t2 | exon | g2265.t2.exon4 | 16345373 | 16345578 |
| chr_3 | g2265 | g2265.t2 | cds | g2265.t2.CDS4 | 16345373 | 16345578 |
| chr_3 | g2265 | g2265.t2 | exon | g2265.t2.exon5 | 16345641 | 16345885 |
| chr_3 | g2265 | g2265.t2 | cds | g2265.t2.CDS5 | 16345641 | 16345885 |
| chr_3 | g2265 | g2265.t2 | TSS | g2265.t2 | 16345921 | 16345921 |
| chr_3 | g2265 | g2265.t2 | TTS | g2265.t2 | NA | NA |
Sequences
>g2265.t2 Gene=g2265 Length=1311
ATGATAAATTTATTCCGTAGATTTAAAATACTATCTCAAAATGTCATTAAAACTTCATTT
AGTGAAAAACATTTACTTACAACTAATTGTATAATTAGCGTTTCATTGAGTTCAGTTGGC
GACATAATAGAACAAAATTTAGAAATCTATAGAAAAGAAATTAAAGCATGGGATAAAATT
AGAACTCGAAACATGGCTACTTCAGGTTTAACTGTTGGCGTGTTTTGTCATTTTTGGTAT
CAATACTTAGATAGCAAACTTCCCGGACGAACATTTAAAACTGTTATGAGAAAAGTACTT
GTTGATCAAATTATAGCATCGCCCATCGTTATTTCTCTTTTCTTTATTACTCTTGGAGTT
GTGCGAAGAGAATCATTAGAAGAGACAATGAATGAAATAAGACAAAAATTTATTAGACTA
TATAAAGCAGAATGGATTGTTTGGCCTACAGCACAAGTTATCAATTTTTGGATATTACCA
TTGAAGTACAGAGTATTGTATGACAACACAATTTCATTAGGATATGATGTCTATACATCC
TATGTAATTAATGAACGAATAGAACATTCTTTATCAGTGACTGCAAACGATACCAAAATT
TGAGTAATACGATGTACTTCATGACTTATGCAGACGAAAATAGTTGAAGTTAAAATGATG
TTGAGAGTTGGAAATCCTGGCAGCAATACTAATACTCCATGACGATCAGCAGCTAGCCAT
ATATGATGCATACAGATAAAAAGTTCCAAAGAAATCTTGCCAAACCAACTGAAGAACGTT
GAAAATCGTGTCCGAAGTACACCCGAAATATTTCTTAAAATAATGAAACTTATGATGGGA
ATAAATACTACATATGAATGAATTTCTTCACAATCTTGCTTGTTTTTGCAGAAAAATGTA
AAAATTGTATAAAATACAATTCCAGTAATTGCCAAAAGTGTTGACGATAAGGAGATTCTG
CGTGAGAAAAGATTTCCATGATTCGAGTCATCAAATATATTGAATTTTTGAGCAGCGATA
CACATCGAAGCAAATATCATCCCATATGCTGTTGAATAACGATCCAATTTGAAGCGATAC
CACCATTCATTCATTAAATCATCAGTGCTCACAAATAATGCTCTCCACGGTCTCATAAGA
AATATTCTCTCAAAAAATACTTCTGACATATATAGAATTGTTATCACACTAAGTAGACAT
ATGAATTTGATCACCAAATAGAGATAATGAATGGAATTATTTTCAACTGTCTGTGCTGAG
ATGAACGGTGGTAAGGAAAATGTGATATATGTTATGCTGAACCAGAAGCTG
>g2265.t2 Gene=g2265 Length=200
MINLFRRFKILSQNVIKTSFSEKHLLTTNCIISVSLSSVGDIIEQNLEIYRKEIKAWDKI
RTRNMATSGLTVGVFCHFWYQYLDSKLPGRTFKTVMRKVLVDQIIASPIVISLFFITLGV
VRRESLEETMNEIRQKFIRLYKAEWIVWPTAQVINFWILPLKYRVLYDNTISLGYDVYTS
YVINERIEHSLSVTANDTKI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g2265.t2 | PANTHER | PTHR11266:SF8 | MPV17-LIKE PROTEIN 2 | 9 | 186 | 1.2E-69 |
| 3 | g2265.t2 | PANTHER | PTHR11266 | PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 | 9 | 186 | 1.2E-69 |
| 1 | g2265.t2 | Pfam | PF04117 | Mpv17 / PMP22 family | 119 | 180 | 1.1E-21 |
| 6 | g2265.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 64 | - |
| 9 | g2265.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 65 | 83 | - |
| 8 | g2265.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 84 | 102 | - |
| 10 | g2265.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 103 | 121 | - |
| 7 | g2265.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 122 | 200 | - |
| 4 | g2265.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 65 | 84 | - |
| 5 | g2265.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 99 | 121 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K13348 (protein Mpv17)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
