General information for g2283.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Set1/Ash2 histone methyltransferase complex subunit ASH2.
Parent gene
- The parent gene g2283 is located on chr_3: 16463808..16464482 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2283 | g2283.t1 | TSS | g2283.t1 | 16461843 | 16461843 |
| chr_3 | g2283 | g2283.t1 | isoform | g2283.t1 | 16461965 | 16464482 |
| chr_3 | g2283 | g2283.t1 | exon | g2283.t1.exon1 | 16461965 | 16462023 |
| chr_3 | g2283 | g2283.t1 | cds | g2283.t1.CDS1 | 16461965 | 16462023 |
| chr_3 | g2283 | g2283.t1 | exon | g2283.t1.exon2 | 16462405 | 16462895 |
| chr_3 | g2283 | g2283.t1 | cds | g2283.t1.CDS2 | 16462405 | 16462895 |
| chr_3 | g2283 | g2283.t1 | exon | g2283.t1.exon3 | 16463345 | 16463746 |
| chr_3 | g2283 | g2283.t1 | cds | g2283.t1.CDS3 | 16463345 | 16463746 |
| chr_3 | g2283 | g2283.t1 | exon | g2283.t1.exon4 | 16463799 | 16464340 |
| chr_3 | g2283 | g2283.t1 | cds | g2283.t1.CDS4 | 16463799 | 16464340 |
| chr_3 | g2283 | g2283.t1 | exon | g2283.t1.exon5 | 16464393 | 16464482 |
| chr_3 | g2283 | g2283.t1 | cds | g2283.t1.CDS5 | 16464393 | 16464482 |
| chr_3 | g2283 | g2283.t1 | TTS | g2283.t1 | 16464519 | 16464519 |
Sequences
>g2283.t1 Gene=g2283 Length=1584
ATGGATAATGTACAAGAAAGTAATCAAATTTTTGAAAATAAGGAAAAAATTTGTTATTGT
GGCAAAGAGAGAAACTTAAGCATAGTTGAAGTCGCCTGTTCCAGTTGTCAAAGATTTTTT
CATGAATCATGTATCGGCTATCAGTTTGGCAAAATCTTGTCATTTTCAATGAACTATATC
TTTACATGCAAATTTTGTTCTGCAACCGGATTAGAAACTTATCGACGAACAAGTGCAACA
ATTCCTCAAATGTGCATAACAACTATAGCTAATTTGCAGAGAAAAAGCGAAAAAGATGGA
TCTCCTAGATTTTTCTTTAGAAAAGATGAAATAATTTCGTTCATTGATATGTATTGGGAA
TCAATAACTACATTAGCTCGAAAACAAACAAGCGGTTGGCATCTTACAATCTATAAAACT
CTTCAATCTCATCAAAATCTTTTTCTCAGTCAAGAAAATGGTTCAGAAGTATTATATGGG
CTTGCTGACACTGATCTCACTAACATTAAACCACAGTATGAAAATAATAAAATTGGTCAA
AAAGATGAAGCTAATCAAAATCTGTCTAAAGCTGGACGGCAACCGAAAAGAAAGTTGACA
GGAAATGAAGCTGTAACCGGTACTGTGGGTAAAAAGGGTCGACCAGCTGCATCAGATCTT
TCAGCAATTATAAATAAATTACCAGCACACGGGTATCCCTTAGAACATCCCTTTAACAAG
GACGGGTATAGATATGTTCTTGCTGAGCCCGACCCGCACGCACCATTTCGACAAGAATAT
GATGAGTCTCCAGATTGGGCTGGAAAACCAATTCCCGGCTGGCTATATCGAGTGCTTACT
CCTAATGCTGTATTAGTTGCTCTTCATGATCGTGCCCCTCAAATGAAAATTTCAGAGGAT
CGATTGTCTGTAACTGGAGATAAAGGTTATTGCATGAGTAGATGCACACATTTTGTAACA
CGAGGATCTTGGTATTGGGAAGCAACTATTGAAGAAATGCCAGAAGGATCAGCTACTAGA
ATTGGCTTCGGGCAAGAATATGCTAATCTACAGTCACCCCTCGGATATGACAAATTTGGT
TATTCGTGGCGTTCACGCAAAGGAACAAAATTTCATGAGTCACATGGAAAGCATTATAGC
GATGGATATGGAGAAGGTGATACGCTTGGTTTCTTGATTATTCTTCCTGAGCAAGAAGGA
GTAAGATATTTACCTAACACTTATAAGGAAAGACCTCTTGTTAAATTTAAAAGTCATTTG
TACTACGAAGACAAGGATAAAGTTAGTGATACACTGAAAAATTTAAAAATTCATCCTGAC
AGTAAGATTATATTCTTCAAAAATGGAAAATGTCAAGGTATTGCGTTTGAAAATATCTAT
AGTGGAGCATATTATCCATCGATTTCAATTCATAAAAATGCAACTGTAAGCTTAAATTTT
GGAGCAGAGGAGTTTAAATATCCTGAAATTTTGAAAGAATACAACTGTAGTCCAATGCAT
GATCGTGTTGAAGCATTCATTTGTGAACAAACTATGGCTGACATGTTTTTCTTTACTGAA
AATGATGGTAAATTAAGACTTTAA
>g2283.t1 Gene=g2283 Length=527
MDNVQESNQIFENKEKICYCGKERNLSIVEVACSSCQRFFHESCIGYQFGKILSFSMNYI
FTCKFCSATGLETYRRTSATIPQMCITTIANLQRKSEKDGSPRFFFRKDEIISFIDMYWE
SITTLARKQTSGWHLTIYKTLQSHQNLFLSQENGSEVLYGLADTDLTNIKPQYENNKIGQ
KDEANQNLSKAGRQPKRKLTGNEAVTGTVGKKGRPAASDLSAIINKLPAHGYPLEHPFNK
DGYRYVLAEPDPHAPFRQEYDESPDWAGKPIPGWLYRVLTPNAVLVALHDRAPQMKISED
RLSVTGDKGYCMSRCTHFVTRGSWYWEATIEEMPEGSATRIGFGQEYANLQSPLGYDKFG
YSWRSRKGTKFHESHGKHYSDGYGEGDTLGFLIILPEQEGVRYLPNTYKERPLVKFKSHL
YYEDKDKVSDTLKNLKIHPDSKIIFFKNGKCQGIAFENIYSGAYYPSISIHKNATVSLNF
GAEEFKYPEILKEYNCSPMHDRVEAFICEQTMADMFFFTENDGKLRL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g2283.t1 | CDD | cd12872 | SPRY_Ash2 | 295 | 485 | 3.32227E-71 |
| 6 | g2283.t1 | Gene3D | G3DSA:1.10.10.2760 | - | 22 | 183 | 9.6E-49 |
| 11 | g2283.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 177 | 202 | - |
| 12 | g2283.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 177 | 193 | - |
| 3 | g2283.t1 | PANTHER | PTHR10598 | SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 | 29 | 517 | 5.5E-145 |
| 2 | g2283.t1 | Pfam | PF00622 | SPRY domain | 324 | 393 | 4.6E-5 |
| 1 | g2283.t1 | Pfam | PF00622 | SPRY domain | 440 | 481 | 6.9E-5 |
| 8 | g2283.t1 | ProSitePatterns | PS01359 | Zinc finger PHD-type signature. | 18 | 66 | - |
| 13 | g2283.t1 | ProSiteProfiles | PS50188 | B30.2/SPRY domain profile. | 263 | 485 | 12.61 |
| 9 | g2283.t1 | SMART | SM00249 | PHD_3 | 17 | 67 | 0.0043 |
| 10 | g2283.t1 | SMART | SM00449 | SPRY_3 | 321 | 484 | 7.0E-30 |
| 5 | g2283.t1 | SUPERFAMILY | SSF57903 | FYVE/PHD zinc finger | 10 | 75 | 1.42E-9 |
| 4 | g2283.t1 | SUPERFAMILY | SSF49899 | Concanavalin A-like lectins/glucanases | 243 | 488 | 1.52E-38 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0048188 | Set1C/COMPASS complex | CC |
| GO:0005515 | protein binding | MF |
| GO:0051568 | histone H3-K4 methylation | BP |
KEGG
Orthology
- This transcript has been annotated with K14964 (Set1/Ash2 histone methyltransferase complex subunit ASH2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
