General information for g2287.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Ovarian-specific serine/threonine-protein kinase Lok.
Parent gene
- The parent gene g2287 is located on chr_3: 16491580..16492403 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2287 | g2287.t5 | TSS | g2287.t5 | 16490758 | 16490758 |
| chr_3 | g2287 | g2287.t5 | isoform | g2287.t5 | 16491469 | 16492403 |
| chr_3 | g2287 | g2287.t5 | exon | g2287.t5.exon1 | 16491469 | 16491512 |
| chr_3 | g2287 | g2287.t5 | cds | g2287.t5.CDS1 | 16491486 | 16491512 |
| chr_3 | g2287 | g2287.t5 | exon | g2287.t5.exon2 | 16491580 | 16491748 |
| chr_3 | g2287 | g2287.t5 | cds | g2287.t5.CDS2 | 16491580 | 16491748 |
| chr_3 | g2287 | g2287.t5 | exon | g2287.t5.exon3 | 16491803 | 16492051 |
| chr_3 | g2287 | g2287.t5 | cds | g2287.t5.CDS3 | 16491803 | 16492051 |
| chr_3 | g2287 | g2287.t5 | exon | g2287.t5.exon4 | 16492110 | 16492403 |
| chr_3 | g2287 | g2287.t5 | cds | g2287.t5.CDS4 | 16492110 | 16492192 |
| chr_3 | g2287 | g2287.t5 | TTS | g2287.t5 | 16492615 | 16492615 |
Sequences
>g2287.t5 Gene=g2287 Length=756
ATTTGCTTTTTGATTTGATGGGTGGTGGAGATTTATTGAAACGCATTGTTGATTCTCCAG
ATAGACGTCTTTCAGAAACGGACTCGAAATTTTTCTTTTTACAATTAGTTAAAGGCGTAA
ATTATTTGCACAGCAATCATGTCACTCATCGAGATATCAAAGCAGAAAATGTTTTTCTTT
CCAATCGTGGCATTTCACCTTTATTAAGAATCGGCGATTTTGGTTTGAGTAAGATCTCTG
ACGCGATGAGTACTATTTGTGGTACTCTCTTATATACTGCGCCCGAAGTTTTCGAGTCAT
CTTTGTATTCACAAAAAGTTGATATATGGAGTTTAGGTTGCTTGCTTTATGCAATGCTTT
CAGGAAAAGTCCCGTTCGCAGATCAAGGAAGTGGAAACGAAAAATTGCTCGAAGAAAAAA
TTAAAAAAGCCGAATACAGTTTGAAAGGATTTAACCATGTAAGTCTCTTTAAGTTCAAAA
AATCTCATAAATCACATGCTGCAAAAGAACCCTGCACTTCGTTTGGACACCACTCAAATC
TTTAAACACGACTGGTTAATTGATCAAACGAACTTTGAAAGACTTATGAAAACTTACCAA
AATCATGGATTTCCTGAAAATGAATGTCGTGAAGAATTGTTAATGGTGATGCAGCTTCAA
AATTTGGCTATTACAGAAAATCGACAAAAACTATATGCTGATAACAATCTTCATTACAGC
GATATGCAGGCTGCAAAACGACAACGACTTCAATAA
>g2287.t5 Gene=g2287 Length=175
MGGGDLLKRIVDSPDRRLSETDSKFFFLQLVKGVNYLHSNHVTHRDIKAENVFLSNRGIS
PLLRIGDFGLSKISDAMSTICGTLLYTAPEVFESSLYSQKVDIWSLGCLLYAMLSGKVPF
ADQGSGNEKLLEEKIKKAEYSLKGFNHVSLFKFKKSHKSHAAKEPCTSFGHHSNL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g2287.t5 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 1 | 166 | 1.4E-45 |
| 2 | g2287.t5 | PANTHER | PTHR44167 | OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED | 2 | 142 | 3.1E-39 |
| 1 | g2287.t5 | Pfam | PF00069 | Protein kinase domain | 3 | 132 | 4.2E-38 |
| 5 | g2287.t5 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 42 | 54 | - |
| 7 | g2287.t5 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 175 | 31.326 |
| 4 | g2287.t5 | SMART | SM00220 | serkin_6 | 1 | 175 | 6.2E-13 |
| 3 | g2287.t5 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 137 | 6.65E-44 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
