General information for g229.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dynamin-1-like protein.
Parent gene
- The parent gene g229 is located on chr_3: 1879971..1882055 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g229 | g229.t1 | isoform | g229.t1 | 1879971 | 1882055 |
| chr_3 | g229 | g229.t1 | exon | g229.t1.exon1 | 1879971 | 1880082 |
| chr_3 | g229 | g229.t1 | cds | g229.t1.CDS1 | 1879971 | 1880082 |
| chr_3 | g229 | g229.t1 | exon | g229.t1.exon2 | 1880141 | 1881607 |
| chr_3 | g229 | g229.t1 | cds | g229.t1.CDS2 | 1880141 | 1881607 |
| chr_3 | g229 | g229.t1 | exon | g229.t1.exon3 | 1881667 | 1882055 |
| chr_3 | g229 | g229.t1 | cds | g229.t1.CDS3 | 1881667 | 1882055 |
| chr_3 | g229 | g229.t1 | TTS | g229.t1 | 1882256 | 1882256 |
| chr_3 | g229 | g229.t1 | TSS | g229.t1 | NA | NA |
Sequences
>g229.t1 Gene=g229 Length=1968
ATGAAAGAATTAATCAGTGCCATTAATAAACTTCAAGATGTGTTCAACACACTTAATTTA
CCAAACAGCATTCAATTGCCACAAATTGTTATGCTAGGATCGCAATCAACAGGCAAAAGT
TCTGTGCTTGAATCGATTGTTCGAAGACCATTTTTACCTCGTGGATCTGGAATTGTGACT
CGTTGTCCATTAGTATTGCAATTGATTGAATGTTCACTTGATGATCGCAAATATCGACGT
GAAAATAATGGAACAATTGATGTCAAAGAATGGGGTGTGTTTTTGCATGATAAAGATAGA
ATTTTTACTGATTTTGATGAAATACGAAAAGAAATTGAAGATCAAACAGATCTTATTGCT
GGAAGTAGCAAAGGCATATGTGCAGAACCGATCAATTTAAAAATTTTCTCACCAGAAGTT
GTCAATTTAACTCTTGTCGATTTGCCTGGTATTACAAAAGTTCCTGTTGGCGACCAACCG
GAAGATATTGAAGATCAAATCAAGAGTCTTGTTATGGAATATATCAAAAATCCAAATTCA
ATCATTTTGAGTGTTAGTGCAGCAAATGTTGATTTGGCAACAAGTGAAAGCTTGAAATAT
GCAAAAGAAGTCGATCCTGATGGCAAACGAACATTAGCTGTTTTGACTAAAATTGATTTG
ATGGATGCAGGTACTGATGCGAATGAAATGCTTACTGGTGCAGTTATTCCTGTAAAACTT
GGTATTGTTGGTGTCATCAATCGTTCACAACTTGATATCAATAATAATAAAACTATCGCT
GAGCAACTTGAGGATGAAAAAGAGTACTTTGCCAAAAACTATAAGAAGATTGCAAGTCAT
AATGGAATTCCTCATCTTGAGCAACGTTTGAGCAAGTTATTGATGAACCATATTTACGAA
TGTTTGCCAAATCTCAAGAAGGAAGTTCAAATGAAGCGTGTTGAATGGCAAAACATTTTT
GATCAATGTGGTGAAGAACTCACCAATCCTGATAGAATTTTTATGAAGATTATCACAAGT
ATTACAAACGATTTTCGCGGTAGCATTGATGGCACAACATTAAAAGTTGAACGCAATGCT
AAAAAAGTTTTTGGTGGACCAGCTATGCGAAAAGTTTTTGATGAGATTTTTGCAAAAGAA
ATTGAGAAAATAGAGCCTCAAATTTCAAAGCAAGATATTATTGTCTACATGAATCACAGT
GGTGGACCAAGACCAGATGTTTTTGCACCTGAAAAGTTGTTTGAAAAACTCATAAAAGAG
AACATTGAGCGTTTGCAAGCTCCATCGCTCGATTGCTTGCAACACATTCATAACGAAATC
GATAAAGTCATCAAAATGATTCTCAAAAATAATTTCGAGTTGAATCGTTTTCCAAAGTTG
GCAGGAAGAATCAAATATATGCTTATTGAATTTTTGAATGAGCGTTTACCAGAAACAGAA
AGTTATCTAAAATATTTGATCAAAGCTGAGTTGGCATCTATCAATAAGAATCATCCAGAG
TTTTCAATTGAAGAAGCACTTAAGAGTTTAAGCATGGAAGAAGAAAACAAAGAAGATGGT
CTCATACAAGATGGCAAAGCATTTTCATTTGCTTCTGCTCATACTAATGTTAATTCTTCA
TTTGCTTTTGATAAAACAAAAGTTGAAAGTAAGACACAAACAAGAGCTAAAGTACAACAA
GACAAAATTAAACGCCATGCTGAAGTCATTGAATCTCTCGTCAACAATTATTTTCCAATC
GTAAAGAAAACTGTGCAAGATTTAACTCCCAAAATCATCATGCTTTCAATGGTCAATGAC
ATGTGTGACAGTATTGATAGCAAGTTATTGGTTTTGTATAAAGATATTGATGAATTGTTG
AACGAGTCTAAAGATAACACTGATAAACGTAATGAAGCAAAGGATATGTTGAAAGCTCTA
AAAATTGCTGATTCAACTATAAATCAAGTTTATGAAAGTGAAGTTTAA
>g229.t1 Gene=g229 Length=655
MKELISAINKLQDVFNTLNLPNSIQLPQIVMLGSQSTGKSSVLESIVRRPFLPRGSGIVT
RCPLVLQLIECSLDDRKYRRENNGTIDVKEWGVFLHDKDRIFTDFDEIRKEIEDQTDLIA
GSSKGICAEPINLKIFSPEVVNLTLVDLPGITKVPVGDQPEDIEDQIKSLVMEYIKNPNS
IILSVSAANVDLATSESLKYAKEVDPDGKRTLAVLTKIDLMDAGTDANEMLTGAVIPVKL
GIVGVINRSQLDINNNKTIAEQLEDEKEYFAKNYKKIASHNGIPHLEQRLSKLLMNHIYE
CLPNLKKEVQMKRVEWQNIFDQCGEELTNPDRIFMKIITSITNDFRGSIDGTTLKVERNA
KKVFGGPAMRKVFDEIFAKEIEKIEPQISKQDIIVYMNHSGGPRPDVFAPEKLFEKLIKE
NIERLQAPSLDCLQHIHNEIDKVIKMILKNNFELNRFPKLAGRIKYMLIEFLNERLPETE
SYLKYLIKAELASINKNHPEFSIEEALKSLSMEEENKEDGLIQDGKAFSFASAHTNVNSS
FAFDKTKVESKTQTRAKVQQDKIKRHAEVIESLVNNYFPIVKKTVQDLTPKIIMLSMVND
MCDSIDSKLLVLYKDIDELLNESKDNTDKRNEAKDMLKALKIADSTINQVYESEV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 18 | g229.t1 | CDD | cd08771 | DLP_1 | 24 | 303 | 1.42232E-130 |
| 16 | g229.t1 | Coils | Coil | Coil | 246 | 266 | - |
| 17 | g229.t1 | Coils | Coil | Coil | 616 | 636 | - |
| 13 | g229.t1 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 312 | 2.1E-110 |
| 14 | g229.t1 | Gene3D | G3DSA:1.20.120.1240 | - | 324 | 523 | 2.5E-40 |
| 15 | g229.t1 | Gene3D | G3DSA:1.20.120.1240 | - | 545 | 621 | 1.3E-11 |
| 4 | g229.t1 | PANTHER | PTHR11566:SF50 | SI:DKEY-32E23.4 | 1 | 653 | 6.1E-187 |
| 5 | g229.t1 | PANTHER | PTHR11566 | DYNAMIN | 1 | 653 | 6.1E-187 |
| 8 | g229.t1 | PRINTS | PR00195 | Dynamin signature | 26 | 44 | 4.3E-56 |
| 10 | g229.t1 | PRINTS | PR00195 | Dynamin signature | 51 | 68 | 4.3E-56 |
| 7 | g229.t1 | PRINTS | PR00195 | Dynamin signature | 137 | 154 | 4.3E-56 |
| 6 | g229.t1 | PRINTS | PR00195 | Dynamin signature | 187 | 205 | 4.3E-56 |
| 11 | g229.t1 | PRINTS | PR00195 | Dynamin signature | 206 | 222 | 4.3E-56 |
| 9 | g229.t1 | PRINTS | PR00195 | Dynamin signature | 229 | 248 | 4.3E-56 |
| 3 | g229.t1 | Pfam | PF00350 | Dynamin family | 29 | 218 | 8.8E-49 |
| 2 | g229.t1 | Pfam | PF01031 | Dynamin central region | 229 | 504 | 2.8E-71 |
| 1 | g229.t1 | Pfam | PF02212 | Dynamin GTPase effector domain | 564 | 650 | 9.6E-20 |
| 21 | g229.t1 | ProSitePatterns | PS00410 | Dynamin-type guanine nucleotide-binding (G) domain signature. | 52 | 61 | - |
| 22 | g229.t1 | ProSiteProfiles | PS51718 | Dynamin-type guanine nucleotide-binding (G) domain profile. | 23 | 303 | 60.099 |
| 23 | g229.t1 | ProSiteProfiles | PS51388 | GED domain profile. | 567 | 655 | 17.735 |
| 20 | g229.t1 | SMART | SM00053 | dynamin_3 | 1 | 256 | 2.2E-109 |
| 19 | g229.t1 | SMART | SM00302 | GED_2 | 562 | 650 | 1.5E-16 |
| 12 | g229.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 1 | 310 | 1.97E-72 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005525 | GTP binding | MF |
| GO:0003924 | GTPase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
