General information for g2336.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Organic cation transporter protein.
Parent gene
- The parent gene g2336 is located on chr_3: 16895470..16896052 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2336 | g2336.t1 | TTS | g2336.t1 | 16892557 | 16892557 |
| chr_3 | g2336 | g2336.t1 | isoform | g2336.t1 | 16892882 | 16896052 |
| chr_3 | g2336 | g2336.t1 | exon | g2336.t1.exon1 | 16892882 | 16893367 |
| chr_3 | g2336 | g2336.t1 | cds | g2336.t1.CDS1 | 16892882 | 16893367 |
| chr_3 | g2336 | g2336.t1 | exon | g2336.t1.exon2 | 16893420 | 16894004 |
| chr_3 | g2336 | g2336.t1 | cds | g2336.t1.CDS2 | 16893420 | 16894004 |
| chr_3 | g2336 | g2336.t1 | exon | g2336.t1.exon3 | 16895456 | 16896052 |
| chr_3 | g2336 | g2336.t1 | cds | g2336.t1.CDS3 | 16895456 | 16896052 |
| chr_3 | g2336 | g2336.t1 | TSS | g2336.t1 | 16896234 | 16896234 |
Sequences
>g2336.t1 Gene=g2336 Length=1668
ATGGTCTCAAAGTTGAATTATGACGACTTGCTCTCTCATATTGGTACATTCGGCGGGTAT
CAATTACGGAATTTTATTTTACTTTGCGTGCCAATAATTTTGTGTGCCTTCCATAAACTC
TCAAGTGTCTTTATACTTGCAAAAATTGATCATAGGTGTCAACTAAACTCAAATGATACA
GAATTTTTGCTCTCTAATAATCAAGATGTTTTATATACTATTCTCACTGCCTCATTTCCA
TATGATGAAAAGAAAGGCTTCTCGAAATGTCAGTACTATTTAGATAATTATTTTAACAGA
GGCGTCGAAAATACTACACATACAGCTGTCGCATGTGACGAGTATGTTTGGGACTATGAA
AAATTTCAATCGTCAGCAATTAAAACATTTAAATTGATTTGTGACCGAGATCACTTTAAG
GCAACAAGCGATTCAGTTTTTATGATTGGAGTTTTCATCGGAAGTTTTGCCTTTGGCCAT
TTATCGGACAAATATGGACGCCGCAAAGTGTTTGTGCTTTCACTAATATTTCAATTGATC
TTTGGCTTGCTGACTGCTCTTGCTACAAATTTTTATACATTTACTATTTTTAGAATGATT
GTCGGAGCAACAACCTCAGGCGTTTTTCTCGTCGCTTATTGCCTATCACTTGAAATGGTG
GGTAAAGAATCACGGATGGTAGCCGGTGTTGTCTTTATGATGTTCTTCTCATCGGGTTAT
ATCTTAATGGGTTTTTTGGCATTTATAATTACTGATTGGCGATGGTATCAAATTGCAATT
ACAATGCCAGGTTTTATTTTTCTAACATATTGGTGGTTCATACCAGAAAGTACGCGATGG
CTTCTTGCAAATAACAAAAAACAAAAGGCTGTGAAACAAATCAAGAAAATTGCATTAAGC
AATAATGTTGAATTGCCAAAAGAAATGTTGGATAAATTGATTGAAACAGAAACTGAAAAT
AATACTGATGAGAATGAAAGCAAACCATCAGTTTTTGATCTTTTTAAACTTCCTCATCTT
CGAACAAAAGCTTTTCTTATATTTTTCAATTGGTTTGTTGTCAGCGGTGCATATTATGGT
TTGAGCTGGAGTAGCGGAGATTTGATAGGCAATCCTCGTTTTAATCATATTATCAGCGGA
TTTGTAGAACTTCCTGGATACGTTTTATTACTTTTGACTTTGAATCGATTTGGACGTAAA
AAAGTTTTAGCCGGTAATTTAACGTTTGCTGGAATTGTATTACTATTATCACTCGCTGTT
CCACAAGATATAACATGGCTAGTGATTACATTGACAATGCTTGGAAAGATGAGCATTACT
GCATCATACGGAACAATTTATTTATTTTCTGTAGAACAGTTTCCAACAGTCATACGAAAT
GTTGCATTAGGCTGTTGTTCAATGTCAGCAAGAGTCGGTTCAACAATATCGCCATATCTC
TTATACCTTGCAAACACATGGCAGCCTTTACCAATTCTGATCTTTGGTCTAACTGCTTTC
ATCGGCGGATTTTTCTCCTTATTTTTGCCAGAAACTTATAATAAAGACTTGCCCGATACA
TTGGCTGATGCTGAAATTAATGACTTAAAAATGATCGAAGTACCTATTGGTGAAGAACTT
AAAGAATTAAACAAAAATGACAATAAAAATCCAACATCTGACGCTTAA
>g2336.t1 Gene=g2336 Length=555
MVSKLNYDDLLSHIGTFGGYQLRNFILLCVPIILCAFHKLSSVFILAKIDHRCQLNSNDT
EFLLSNNQDVLYTILTASFPYDEKKGFSKCQYYLDNYFNRGVENTTHTAVACDEYVWDYE
KFQSSAIKTFKLICDRDHFKATSDSVFMIGVFIGSFAFGHLSDKYGRRKVFVLSLIFQLI
FGLLTALATNFYTFTIFRMIVGATTSGVFLVAYCLSLEMVGKESRMVAGVVFMMFFSSGY
ILMGFLAFIITDWRWYQIAITMPGFIFLTYWWFIPESTRWLLANNKKQKAVKQIKKIALS
NNVELPKEMLDKLIETETENNTDENESKPSVFDLFKLPHLRTKAFLIFFNWFVVSGAYYG
LSWSSGDLIGNPRFNHIISGFVELPGYVLLLLTLNRFGRKKVLAGNLTFAGIVLLLSLAV
PQDITWLVITLTMLGKMSITASYGTIYLFSVEQFPTVIRNVALGCCSMSARVGSTISPYL
LYLANTWQPLPILIFGLTAFIGGFFSLFLPETYNKDLPDTLADAEINDLKMIEVPIGEEL
KELNKNDNKNPTSDA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 29 | g2336.t1 | CDD | cd17317 | MFS_SLC22 | 114 | 510 | 8.20106E-111 |
| 5 | g2336.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 111 | 522 | 4.3E-76 |
| 2 | g2336.t1 | PANTHER | PTHR24064 | SOLUTE CARRIER FAMILY 22 MEMBER | 6 | 530 | 6.3E-124 |
| 3 | g2336.t1 | PANTHER | PTHR24064:SF198 | SOLUTE CARRIER FAMILY 22 MEMBER 13 | 6 | 530 | 6.3E-124 |
| 1 | g2336.t1 | Pfam | PF00083 | Sugar (and other) transporter | 145 | 517 | 2.2E-29 |
| 17 | g2336.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 24 | - |
| 26 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 47 | - |
| 10 | g2336.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 48 | 169 | - |
| 22 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 170 | 189 | - |
| 12 | g2336.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 190 | 194 | - |
| 23 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 195 | 215 | - |
| 6 | g2336.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 216 | 226 | - |
| 19 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 227 | 249 | - |
| 13 | g2336.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 250 | 254 | - |
| 18 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 255 | 274 | - |
| 7 | g2336.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 275 | 343 | - |
| 24 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 344 | 361 | - |
| 14 | g2336.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 362 | 372 | - |
| 28 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 373 | 395 | - |
| 9 | g2336.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 396 | 401 | - |
| 21 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 402 | 420 | - |
| 16 | g2336.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 421 | 425 | - |
| 20 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 426 | 449 | - |
| 11 | g2336.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 450 | 460 | - |
| 27 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 461 | 484 | - |
| 15 | g2336.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 485 | 489 | - |
| 25 | g2336.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 490 | 509 | - |
| 8 | g2336.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 510 | 555 | - |
| 41 | g2336.t1 | ProSiteProfiles | PS50850 | Major facilitator superfamily (MFS) profile. | 70 | 514 | 22.713 |
| 4 | g2336.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 144 | 519 | 1.05E-54 |
| 39 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 47 | - |
| 36 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 170 | 189 | - |
| 40 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 194 | 216 | - |
| 37 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 228 | 250 | - |
| 31 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 255 | 274 | - |
| 34 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 344 | 366 | - |
| 38 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 376 | 395 | - |
| 32 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 402 | 421 | - |
| 33 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 426 | 448 | - |
| 35 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 461 | 483 | - |
| 30 | g2336.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 487 | 509 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K08202 (MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
