General information for g2336.t9
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Organic cation transporter protein.
Parent gene
- The parent gene g2336 is located on chr_3: 16895470..16896052 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2336 | g2336.t9 | TTS | g2336.t9 | 16892557 | 16892557 |
| chr_3 | g2336 | g2336.t9 | isoform | g2336.t9 | 16892565 | 16893990 |
| chr_3 | g2336 | g2336.t9 | exon | g2336.t9.exon1 | 16892565 | 16893367 |
| chr_3 | g2336 | g2336.t9 | cds | g2336.t9.CDS1 | 16892882 | 16893367 |
| chr_3 | g2336 | g2336.t9 | exon | g2336.t9.exon2 | 16893420 | 16893990 |
| chr_3 | g2336 | g2336.t9 | cds | g2336.t9.CDS2 | 16893420 | 16893947 |
| chr_3 | g2336 | g2336.t9 | TSS | g2336.t9 | NA | NA |
Sequences
>g2336.t9 Gene=g2336 Length=1374
AACCTCAGGCGTTTTTCTCGTCGCTTATTGCCTATCACTTGAAATGGTGGGTAAAGAATC
ACGGATGGTAGCCGGTGTTGTCTTTATGATGTTCTTCTCATCGGGTTATATCTTAATGGG
TTTTTTGGCATTTATAATTACTGATTGGCGATGGTATCAAATTGCAATTACAATGCCAGG
TTTTATTTTTCTAACATATTGGTGGTTCATACCAGAAAGTACGCGATGGCTTCTTGCAAA
TAACAAAAAACAAAAGGCTGTGAAACAAATCAAGAAAATTGCATTAAGCAATAATGTTGA
ATTGCCAAAAGAAATGTTGGATAAATTGATTGAAACAGAAACTGAAAATAATACTGATGA
GAATGAAAGCAAACCATCAGTTTTTGATCTTTTTAAACTTCCTCATCTTCGAACAAAAGC
TTTTCTTATATTTTTCAATTGGTTTGTTGTCAGCGGTGCATATTATGGTTTGAGCTGGAG
TAGCGGAGATTTGATAGGCAATCCTCGTTTTAATCATATTATCAGCGGATTTGTAGAACT
TCCTGGATACGTTTTATTACTTTTGACTTTGAATCGATTTGGACGTAAAAAAGTTTTAGC
CGGTAATTTAACGTTTGCTGGAATTGTATTACTATTATCACTCGCTGTTCCACAAGATAT
AACATGGCTAGTGATTACATTGACAATGCTTGGAAAGATGAGCATTACTGCATCATACGG
AACAATTTATTTATTTTCTGTAGAACAGTTTCCAACAGTCATACGAAATGTTGCATTAGG
CTGTTGTTCAATGTCAGCAAGAGTCGGTTCAACAATATCGCCATATCTCTTATACCTTGC
AAACACATGGCAGCCTTTACCAATTCTGATCTTTGGTCTAACTGCTTTCATCGGCGGATT
TTTCTCCTTATTTTTGCCAGAAACTTATAATAAAGACTTGCCCGATACATTGGCTGATGC
TGAAATTAATGACTTAAAAATGATCGAAGTACCTATTGGTGAAGAACTTAAAGAATTAAA
CAAAAATGACAATAAAAATCCAACATCTGACGCTTAATTAATTATTTTAATCGAATCATT
TCCACATTCCCTACCATTGTTTTTAATCTCTAATGTACTTAGAAGACTTTAATAAGAAAT
AATTTTATAAATTATTGATGACTACGAGAGAAATTTTTATTTAGATTTAATGTATGTATT
AAATACGCAATCAATTATAATAAAAAATCTCAATCAATATTGATCAAAAAGGCAAATGCA
ATTAATTTCTCTCATGATGATTTATTTACAAGGGAAACTTTTCTTCTGTTTAAGACTAGA
CAATAAAGTTGACGAAAATTTTTTTACTTAATAAAATTTACAATTTAATGGTAT
>g2336.t9 Gene=g2336 Length=337
MVGKESRMVAGVVFMMFFSSGYILMGFLAFIITDWRWYQIAITMPGFIFLTYWWFIPEST
RWLLANNKKQKAVKQIKKIALSNNVELPKEMLDKLIETETENNTDENESKPSVFDLFKLP
HLRTKAFLIFFNWFVVSGAYYGLSWSSGDLIGNPRFNHIISGFVELPGYVLLLLTLNRFG
RKKVLAGNLTFAGIVLLLSLAVPQDITWLVITLTMLGKMSITASYGTIYLFSVEQFPTVI
RNVALGCCSMSARVGSTISPYLLYLANTWQPLPILIFGLTAFIGGFFSLFLPETYNKDLP
DTLADAEINDLKMIEVPIGEELKELNKNDNKNPTSDA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g2336.t9 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 1 | 304 | 5.0E-51 |
| 2 | g2336.t9 | PANTHER | PTHR24064:SF432 | SOLUTE CARRIER FAMILY 22 MEMBER 2 | 1 | 308 | 1.4E-78 |
| 3 | g2336.t9 | PANTHER | PTHR24064 | SOLUTE CARRIER FAMILY 22 MEMBER | 1 | 308 | 1.4E-78 |
| 1 | g2336.t9 | Pfam | PF00083 | Sugar (and other) transporter | 32 | 299 | 1.4E-15 |
| 16 | g2336.t9 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 11 | - |
| 26 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 31 | - |
| 20 | g2336.t9 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 32 | 36 | - |
| 31 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 37 | 56 | - |
| 19 | g2336.t9 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 57 | 125 | - |
| 25 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 126 | 143 | - |
| 21 | g2336.t9 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 144 | 154 | - |
| 30 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 155 | 177 | - |
| 17 | g2336.t9 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 178 | 183 | - |
| 27 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 184 | 202 | - |
| 22 | g2336.t9 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 203 | 207 | - |
| 29 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 208 | 231 | - |
| 15 | g2336.t9 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 232 | 242 | - |
| 24 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 243 | 266 | - |
| 23 | g2336.t9 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 267 | 271 | - |
| 28 | g2336.t9 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 272 | 291 | - |
| 18 | g2336.t9 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 292 | 337 | - |
| 14 | g2336.t9 | ProSiteProfiles | PS50850 | Major facilitator superfamily (MFS) profile. | 1 | 296 | 11.611 |
| 12 | g2336.t9 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 3 | 301 | 4.32E-32 |
| 9 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 9 | 31 | - |
| 10 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 35 | 57 | - |
| 8 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 126 | 148 | - |
| 6 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 158 | 177 | - |
| 11 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 184 | 203 | - |
| 7 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 208 | 230 | - |
| 5 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 243 | 265 | - |
| 4 | g2336.t9 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 269 | 291 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
