General information for g2337.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein phosphatase 1B.
Parent gene
- The parent gene g2337 is located on chr_3: 16899941..16903773 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2337 | g2337.t8 | TTS | g2337.t8 | 16896666 | 16896666 |
| chr_3 | g2337 | g2337.t8 | isoform | g2337.t8 | 16896837 | 16900537 |
| chr_3 | g2337 | g2337.t8 | exon | g2337.t8.exon1 | 16896837 | 16897292 |
| chr_3 | g2337 | g2337.t8 | exon | g2337.t8.exon2 | 16897364 | 16897466 |
| chr_3 | g2337 | g2337.t8 | exon | g2337.t8.exon3 | 16899432 | 16899549 |
| chr_3 | g2337 | g2337.t8 | exon | g2337.t8.exon4 | 16899606 | 16899731 |
| chr_3 | g2337 | g2337.t8 | cds | g2337.t8.CDS1 | 16899700 | 16899731 |
| chr_3 | g2337 | g2337.t8 | exon | g2337.t8.exon5 | 16899819 | 16900382 |
| chr_3 | g2337 | g2337.t8 | cds | g2337.t8.CDS2 | 16899819 | 16900382 |
| chr_3 | g2337 | g2337.t8 | exon | g2337.t8.exon6 | 16900447 | 16900537 |
| chr_3 | g2337 | g2337.t8 | cds | g2337.t8.CDS3 | 16900447 | 16900537 |
| chr_3 | g2337 | g2337.t8 | TSS | g2337.t8 | NA | NA |
Sequences
>g2337.t8 Gene=g2337 Length=1458
ATGGGAGCATTTTTGGAAAAGCCCAATACAAACAAACACAATGAGAATGGTGAGGGCAAT
GGATTGCGATTTGGAGTGAGTTCAATGCAAGGATGGCGTTGCGAAATGGAAGATGCTCAT
TTTGCAAGAACAAATTTAGGAGAAGATTTGGCAGATTGGAGTTATTTTGCGGTGTTTGAC
GGACATGCAGGTTTTAAAGTGTCTGAACATTGTGCGCAGCATTTATTAGAAGCGATCATA
CACACAGAAGAGTTTAAAGGCAATGATGTTGTGAAGGGAATACACTCTGGCTTCTTAAAA
TTGGATAACATAATGCGAGATATACCTGAATTAGCAAGCGGTGCTGATAAATCTGGAACT
ACTGCCGTTTGTGCATTCATATCAAGTGATAGTATTTATATTGCAAATTGCGGTGATTCA
CGTGCTGTATTGTGTCGAAATGGCAATCCAGTATTCTCAACGCAAGATCACAAACCGATT
CTGCCATCTGAAAAGGAACGAATTGTAAATGCAGGAGGATCGGTTATGGTACAACGTGTC
AACGGTAGCCTCGCAGTATCGAGAGCACTTGGAGATTATGATTACAAAAATGTCTCGGAA
TTGGGTCAATGTGAACAGTTGGTATCACCTGAACCCGAGATTTTCTGCAAAGAACGCTTG
CGACGGTGTATGGGATGTGATGAGTAACGAGGCCGTCTGTAATTTTGTTCATAATCGCCT
TCGAATTTCTGATGACTTGGTGTGGATTTGTAATCAAGTTATTGACACATGCTTGCACAA
GGGTTCTCGCGATAATATGAGCATCATTCTAATAGTATTCCCCGGAGCGCCGAAACCTTC
CAGTGAAGCTATTGAAGCAGAAGAGGAGCTTGAGAGGAATATACGTAAAACTATAAAAGA
ATTCACAGAAAATACGGAGGCTGCATACGATGTGAGTTCATTAATGCGCTTATTAGCCAG
CAGTAACATTCAGTGGCCGGAAGGTGGTGGTATAGAATCTAAATATAAACTTATTACGGA
AGTATTTAAGGAAATCTGTCCTGATCTCACTGATGCAGAATTCGAGTTTTAAAGAAAACC
CTTTTTTACAATAGAATATTGATTATGATTTTCTTTGATAAAAAAAAACAACCTTTGATA
CAATTATTCAGCCAAATAACTATTGGAACAATATTTCAAACTACTATTTCAAATGAAGAA
GAAAATAAGAAATGAGTAAAAATGATATCCGTGATTACAAATGAAGTAGAAATAAGCTGT
TCTAATTTCCATCTTAAAATATTGTACATAAATTTTACTTAAATTTCCTCTTAAATATTC
TAATTTTGACGATTTTTTTTACAATGAAATTCTTTTCCATCAACTTTTTTTTTCTTAAAA
TAAAATCAAATTTACACTTTTACAAACATACGCCAGTTTCTATTTTATGCGTGTGTAATT
AAATATTTAATGATGAGA
>g2337.t8 Gene=g2337 Length=228
MGAFLEKPNTNKHNENGEGNGLRFGVSSMQGWRCEMEDAHFARTNLGEDLADWSYFAVFD
GHAGFKVSEHCAQHLLEAIIHTEEFKGNDVVKGIHSGFLKLDNIMRDIPELASGADKSGT
TAVCAFISSDSIYIANCGDSRAVLCRNGNPVFSTQDHKPILPSEKERIVNAGGSVMVQRV
NGSLAVSRALGDYDYKNVSELGQCEQLVSPEPEIFCKERLRRCMGCDE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g2337.t8 | CDD | cd00143 | PP2Cc | 23 | 227 | 1.89919E-69 |
| 5 | g2337.t8 | Gene3D | G3DSA:3.60.40.10 | Phosphatase 2c; Domain 1 | 1 | 227 | 1.7E-85 |
| 9 | g2337.t8 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 20 | - |
| 2 | g2337.t8 | PANTHER | PTHR47992:SF121 | PROTEIN PHOSPHATASE 1A | 2 | 219 | 7.9E-82 |
| 3 | g2337.t8 | PANTHER | PTHR47992 | ALPHABET, ISOFORM E-RELATED | 2 | 219 | 7.9E-82 |
| 1 | g2337.t8 | Pfam | PF00481 | Protein phosphatase 2C | 23 | 216 | 8.9E-61 |
| 7 | g2337.t8 | ProSitePatterns | PS01032 | PPM-type phosphatase domain signature. | 55 | 63 | - |
| 10 | g2337.t8 | ProSiteProfiles | PS51746 | PPM-type phosphatase domain profile. | 23 | 228 | 37.584 |
| 8 | g2337.t8 | SMART | SM00332 | PP2C_4 | 13 | 225 | 2.8E-52 |
| 4 | g2337.t8 | SUPERFAMILY | SSF81606 | PP2C-like | 3 | 218 | 6.28E-63 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0043169 | cation binding | MF |
| GO:0016791 | phosphatase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed