General information for g2355.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Suppressor of fused-like protein.
Parent gene
- The parent gene g2355 is located on chr_3: 17115191..17116548 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2355 | g2355.t1 | TTS | g2355.t1 | 17115040 | 17115040 |
| chr_3 | g2355 | g2355.t1 | isoform | g2355.t1 | 17115191 | 17116548 |
| chr_3 | g2355 | g2355.t1 | exon | g2355.t1.exon1 | 17115191 | 17115907 |
| chr_3 | g2355 | g2355.t1 | cds | g2355.t1.CDS1 | 17115191 | 17115907 |
| chr_3 | g2355 | g2355.t1 | exon | g2355.t1.exon2 | 17115964 | 17116548 |
| chr_3 | g2355 | g2355.t1 | cds | g2355.t1.CDS2 | 17115964 | 17116548 |
| chr_3 | g2355 | g2355.t1 | TSS | g2355.t1 | 17116618 | 17116618 |
Sequences
>g2355.t1 Gene=g2355 Length=1302
ATGCATAGTAATTTGGCATTAATGCCATCATTTATTTTCCCTGGAATGAGAGCAATCTAT
CAAAGTTTGTTTAGCATATATCGGGAAAGTAATCCACTTGTGATTTCAACAGTAAACAAA
ATATGGCAATTTCCAAATTTAAATACAAACGAGATTTTAGACTACATTTTTATCTACCTA
AATGCTGGCAGCCCCGAAGAACAAGTATGTGAACATTGGCATTATGTGACATTAGGCTTA
TCAGATCTCTATGGAGACAGTCGTATTCATGCTATTGATACAGGAGCAAGTGCCGAAAGA
TTAAGTGGATTCGGCATCGAATTGACATTCAGACTTAAAAAACATAATGAATCTCAACCG
CCAAGTTGGCCAGCGACACTTTTGCAACAACTTGCAAAATACGTTTTTGTTACAAGAAAT
AAATTATTGCCTAATGATTATTTACCATGGAATAAGCCACTTGATGGTATTGAGGAATGT
AAAATAAGACATATGTTGGTTACTCTTGACTGTCAACTTAAAAGAATTAAAACTCCGCTT
GGTCATGTGTCTTTTTGTCAAATTGTTGGTGTTACAGATGAAGAGCTCAACTGTTCTCAA
TCATTTAATGTGAAGAACATTCTCGAAGTTCTAAAGCAAGATCAATCAACTGGTGGAATT
TCATTAATAACAGACATGACTCGTAAACAAAGTGTTTTCGATCTCTTTCCTCAAACGTTA
AAAATGCTCGAAGAAGATCTCGAACGAGAAGGCTCAGATTTAGCTGGTGTCAATGGAGAA
TTTTTTTATAGAGAGTTACCGAAACTTGCCATTAAAACTTCACTATGCCTTACAATGTCA
GATTCTGAAAAATCATTGGATTTTACAAGGTCATTGGGTAGATTGGATATAAGAACTAGT
GCAGAACTTGCTGCTCATCACTCTTCACCATTTCTGCCATTTGCCAGACAAATCTTTCTT
GATGGTGTTGAAATTATTTTTACACCAAACAGTGCGAAATTCTTAAAACTTGCATTTAAA
TACAGATTATTCAAAGGACATCATTTTACATTTCAATCTCCAGATACTCATTTGACATTT
TTAACTGAAAATGTGAGCGGAAGTTTTGTAACAAATGAACAGCCTTATGGATTAGCTGGA
AAATGGCTTCAAATTCGAATTGAAAAAGACTTTTTGCCAACAATTATCAATGATTTGACA
AATGAATTTAACCCTGAAAACACAGAATTGCCGAAAATCTTTGATTACCCAGAGAAGAAT
TTACGATTCATTATTAACAATTTAGCATTTGGTTTATCTTAA
>g2355.t1 Gene=g2355 Length=433
MHSNLALMPSFIFPGMRAIYQSLFSIYRESNPLVISTVNKIWQFPNLNTNEILDYIFIYL
NAGSPEEQVCEHWHYVTLGLSDLYGDSRIHAIDTGASAERLSGFGIELTFRLKKHNESQP
PSWPATLLQQLAKYVFVTRNKLLPNDYLPWNKPLDGIEECKIRHMLVTLDCQLKRIKTPL
GHVSFCQIVGVTDEELNCSQSFNVKNILEVLKQDQSTGGISLITDMTRKQSVFDLFPQTL
KMLEEDLEREGSDLAGVNGEFFYRELPKLAIKTSLCLTMSDSEKSLDFTRSLGRLDIRTS
AELAAHHSSPFLPFARQIFLDGVEIIFTPNSAKFLKLAFKYRLFKGHHFTFQSPDTHLTF
LTENVSGSFVTNEQPYGLAGKWLQIRIEKDFLPTIINDLTNEFNPENTELPKIFDYPEKN
LRFIINNLAFGLS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g2355.t1 | Gene3D | G3DSA:3.30.1360.230 | - | 305 | 431 | 7.7E-31 |
| 3 | g2355.t1 | PANTHER | PTHR10928 | SUPPRESSOR OF FUSED | 7 | 425 | 1.4E-115 |
| 11 | g2355.t1 | PIRSF | PIRSF011844 | Sufu | 1 | 433 | 7.0E-125 |
| 1 | g2355.t1 | Pfam | PF05076 | Suppressor of fused protein (SUFU) | 53 | 229 | 7.0E-40 |
| 2 | g2355.t1 | Pfam | PF12470 | Suppressor of Fused Gli/Ci N terminal binding domain | 243 | 425 | 7.6E-37 |
| 7 | g2355.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 17 | - |
| 8 | g2355.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 9 | g2355.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 13 | - |
| 10 | g2355.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 17 | - |
| 6 | g2355.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 18 | 433 | - |
| 4 | g2355.t1 | SUPERFAMILY | SSF103359 | Suppressor of Fused, N-terminal domain | 14 | 250 | 1.29E-62 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0008134 | transcription factor binding | MF |
KEGG
Orthology
- This transcript has been annotated with K06229 (suppressor of fused)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
