Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative G protein-coupled receptor kinase 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2428 g2428.t5 isoform g2428.t5 17928396 17930434
chr_3 g2428 g2428.t5 exon g2428.t5.exon1 17928396 17928660
chr_3 g2428 g2428.t5 cds g2428.t5.CDS1 17928396 17928660
chr_3 g2428 g2428.t5 exon g2428.t5.exon2 17928853 17928967
chr_3 g2428 g2428.t5 cds g2428.t5.CDS2 17928853 17928967
chr_3 g2428 g2428.t5 exon g2428.t5.exon3 17929631 17929726
chr_3 g2428 g2428.t5 cds g2428.t5.CDS3 17929631 17929726
chr_3 g2428 g2428.t5 exon g2428.t5.exon4 17930383 17930434
chr_3 g2428 g2428.t5 cds g2428.t5.CDS4 17930383 17930434
chr_3 g2428 g2428.t5 TSS g2428.t5 17931433 17931433
chr_3 g2428 g2428.t5 TTS g2428.t5 NA NA

Sequences

>g2428.t5 Gene=g2428 Length=528
ATGGAGTTAGAGAACATTGTGGCCAATACGGTCTACCTCAAAGCCAGAGAGGGTGGCTCT
GATAGTAACAAAGGAAAGAGCAAGAAATGGCGCAAAATTTTACAATTTCCACACATATCT
CAATGTATAGATCTCAAAAATAAAATAGATGTAAGCTATGATTATGTCGTAGACAAACAA
CCAATTGGAAGAGTATTGTTTCGGCAGTTTTGTCAAGTCAAACAATTTTACAAATATGTA
AAATTCTTAGAAGAAGTATCAAGGTATGAGTTGGAGTCTGATGAAAATCGACAGGCAATT
GCCATTAGAATAGGGCGACAATTTTTGGGTATTGAAGAGGATGAAATTAAAGCGATAGAT
CAGGAGAATGAAAAAACTGACTCGAACAATATCAATCCAAATAATGTTTCATCACCAAAA
AACAACTCATCACAGCTCGATAAAGCTGATGGCCAATCGGAACAGAATGAAATATCTCCC
GTCACTGACATTCTAAATGATGAACTCATTTCAGACTGTAAGCAAAAA

>g2428.t5 Gene=g2428 Length=176
MELENIVANTVYLKAREGGSDSNKGKSKKWRKILQFPHISQCIDLKNKIDVSYDYVVDKQ
PIGRVLFRQFCQVKQFYKYVKFLEEVSRYELESDENRQAIAIRIGRQFLGIEEDEIKAID
QENEKTDSNNINPNNVSSPKNNSSQLDKADGQSEQNEISPVTDILNDELISDCKQK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g2428.t5 Gene3D G3DSA:1.20.58.1850 - 1 173 8.9E-46
5 g2428.t5 MobiDBLite mobidb-lite consensus disorder prediction 121 163 -
6 g2428.t5 MobiDBLite mobidb-lite consensus disorder prediction 125 162 -
2 g2428.t5 PANTHER PTHR24355:SF28 G PROTEIN-COUPLED RECEPTOR KINASE 2 1 131 7.4E-42
3 g2428.t5 PANTHER PTHR24355 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE 1 131 7.4E-42
1 g2428.t5 Pfam PF00615 Regulator of G protein signaling domain 53 133 3.9E-7
8 g2428.t5 ProSiteProfiles PS50132 RGS domain profile. 59 109 12.491
4 g2428.t5 SUPERFAMILY SSF48097 Regulator of G-protein signaling, RGS 31 132 2.35E-17

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

There are no GO annotations for this transcript.

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed