General information for g2439.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ADAM 17-like protease.
Parent gene
- The parent gene g2439 is located on chr_3: 18005856..18007019 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2439 | g2439.t2 | TSS | g2439.t2 | 18004318 | 18004318 |
| chr_3 | g2439 | g2439.t2 | isoform | g2439.t2 | 18004381 | 18005306 |
| chr_3 | g2439 | g2439.t2 | exon | g2439.t2.exon1 | 18004381 | 18004438 |
| chr_3 | g2439 | g2439.t2 | cds | g2439.t2.CDS1 | 18004381 | 18004438 |
| chr_3 | g2439 | g2439.t2 | exon | g2439.t2.exon2 | 18004556 | 18005306 |
| chr_3 | g2439 | g2439.t2 | cds | g2439.t2.CDS2 | 18004556 | 18005304 |
| chr_3 | g2439 | g2439.t2 | TTS | g2439.t2 | 18005673 | 18005673 |
Sequences
>g2439.t2 Gene=g2439 Length=809
ATGGCGAAAATTTTCTTTGCTACATTTCTTGTATTTCTTCACTTATTTGAAGCTCAAACC
CAATTGCATAAAAATTTAAAATACTATGAAACATTACATGCAGATGAAATTACACATAAA
ATTGTCAAAAGGGGAATAAAACCAAGTATCAATTTGCACAATAAAATTAGAGAAGTGGAA
TTTACTGCATTAGGAAAAAAATTCAAATTGATTCTTCATCCACACAGGGATGTTTTGCAT
CAAAATTTTCGTGCAGTTACAGTAAATTCGGAAGGTAATGAAACAGTCGTTCATCTCGAT
CAAGATAGCTTTTTCAGAGGTCGTGTATTTGGAGAGAGTACATCACATGTTTCTGCTCAT
ATTGATGAGAAAAATGTACTCACTGCTACAATAATTTTACCTGATGAAACTTATCATATT
GAACCATCTTGGAGACATCTTGAGAAAAAACTCCCAGAAAGTAGCAACAAACATATGGTT
GCTTATAAAGCGTCAGACGTTAAATTGAGTTGGGAGCATCACAATGAAAATAAAAATGAT
GGAGAGAATCATTTTGTTCCTGGCAGATGTGGATATGTTAAAGAAGGTGCTGAACTTGAA
ACAGATGATGATGATGATGAAATTGAAGAACCAGAAGTTGAAGCATATGGTGGAAACGAA
ACACCGCATAGTGAAAGAAGATCAAAAAGACAAGCTGATCAATATGAATACACTCCAACA
AAAACACGATGTCCTCTTTTACTCGTTGCTGATTATCGTTTTTTCCAAGAAATGGGAAGT
TCAAATACAAAAACTACAATTTCTTATTT
>g2439.t2 Gene=g2439 Length=269
MAKIFFATFLVFLHLFEAQTQLHKNLKYYETLHADEITHKIVKRGIKPSINLHNKIREVE
FTALGKKFKLILHPHRDVLHQNFRAVTVNSEGNETVVHLDQDSFFRGRVFGESTSHVSAH
IDEKNVLTATIILPDETYHIEPSWRHLEKKLPESSNKHMVAYKASDVKLSWEHHNENKND
GENHFVPGRCGYVKEGAELETDDDDDEIEEPEVEAYGGNETPHSERRSKRQADQYEYTPT
KTRCPLLLVADYRFFQEMGSSNTKTTISY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g2439.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 198 | 214 | - |
| 6 | g2439.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 198 | 237 | - |
| 5 | g2439.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 219 | 236 | - |
| 2 | g2439.t2 | PANTHER | PTHR45702:SF6 | DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 | 24 | 267 | 3.1E-41 |
| 3 | g2439.t2 | PANTHER | PTHR45702 | ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER | 24 | 267 | 3.1E-41 |
| 1 | g2439.t2 | Pfam | PF01562 | Reprolysin family propeptide | 39 | 160 | 4.1E-9 |
| 9 | g2439.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 10 | g2439.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 11 | g2439.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 13 | - |
| 12 | g2439.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 8 | g2439.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 269 | - |
| 7 | g2439.t2 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
