General information for g2494.t9
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphoribosyl pyrophosphate synthase-associated protein 2.
Parent gene
- The parent gene g2494 is located on chr_3: 18280776..18288527 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2494 | g2494.t9 | isoform | g2494.t9 | 18279650 | 18281740 |
| chr_3 | g2494 | g2494.t9 | exon | g2494.t9.exon1 | 18279650 | 18280510 |
| chr_3 | g2494 | g2494.t9 | cds | g2494.t9.CDS1 | 18280497 | 18280510 |
| chr_3 | g2494 | g2494.t9 | exon | g2494.t9.exon2 | 18280567 | 18281740 |
| chr_3 | g2494 | g2494.t9 | cds | g2494.t9.CDS2 | 18280567 | 18281389 |
| chr_3 | g2494 | g2494.t9 | TTS | g2494.t9 | 18281730 | 18281730 |
| chr_3 | g2494 | g2494.t9 | TSS | g2494.t9 | NA | NA |
Sequences
>g2494.t9 Gene=g2494 Length=2035
ATGAACAGAAAATCGTAAGTTGGCCTAATTTAATTAATATTTCATCGGTTTTCATATATT
TGCCAGTGTTTCAATTGCTTCAATCTTGTTATAACGTGATTGTTTATCGAAAAATGTCAA
AGTAATCGCAAATTAAGCTAAATAACATAAGAAATTGGCAAAAATATTCCATTCATTAAT
CTCGATTGTTTACAAAAAATTTTAGGAATTAAATTTATCATATTATTTTCTTTAATTCTA
GTTAAAAACCCTTCACTAACTGTTTGCTTGATCACTAGTATCCCAATTTTTCGAAAGTCG
TACATTTGTATTGTCAATGCGCTTCGTCAAAAAAACATAAACATAACACAAATCCATTAC
ATTAGCACGCACAAAATAAAATTTTCGACTGTATAAACAGTTTGATCGATAAGAAATCAC
TCTTCATTCTTGCAATCAATCAACTTGTTCGAATTTTATAGATTTCAACCCGTAAGATCG
TTATCAAACCACTATATGGATTGTCCGTCAACGTCCGACATTGTGCTTCTGCACGGCAAT
TCTTGTCCAGAGTTAGCAAACCTTATTGGCAGGTGAGTGCATGTATAATAAATCTCTGGA
TTATAACATTAACCTGAATTCATTCATCCATAGCCGATTAAATATTAAGTCTGGAGGATG
CTCAGTTTATCACAAGCCAAATCGAGAAACAATGGTTGATATCGGTGACTCTGTGCGCGG
AAAAGATTGCTATATCATACAAACTGGAACAAAGTAAACCGAATGCAAACAATACGTTGA
AATTAGAGTAAATGTTTTTCTTTTCTTATTTAGGGATTGCAACAACAATATTATGGAATT
ATTGATAATGGCATATGCTTGTAAAACATCAAGCGCAAAATCTATTGTTGCTGTTATTCC
TTACTTGCCCTATTCAAAGCAATGTAAGATGCGTAAACGTGGATCAATTGTCACAAAACT
CATTGCTAAAATGATGTGTAATGCTGGATTAACTCATGTTATTACAATGGACTTACATCA
GAAGGAAATTCAAGGATTTTTTGATTGTCCTGTTGATAATCTTCGAGCTTCGCCATTTTT
ACTTCAATATATTCAAGAGTCAATTCCTGATTATCGTAATGCTGTTATTGTCGCTCGTAA
TCCTGGATCGGCTAAAAAAGCTACCTCTTATGCTGAACGTTTACGTTTAGGAATCGCTGT
TATCCATGGTGAACAAAAAGATGCTGATAATGATGAAATTGACGGTCGAAATTCGCCACC
AAATGTTCCAAAAGGACGAATGAGTGATATTTCATCAGGATTTCCAAGTCTCGTTGCTAA
AGAAAAGCCACCGATTAATGTGGTTGGTGATGTGGGAGGCAGAATTGCTGTAATTGTTGA
TGATTTAATAGATGAAGTACAATCATTTGTCTCGGCTGCTGAAGTTCTTAAAGAAAGAGG
AGCTTATAAAATTTATGTTTTGGCAACACATGGTTTGCTTTCTTCTGATGCACCACGCTT
AATTGAAGAATCTGCTATTGATGAAGTTGTCGTTACAAATACTATACCGCATGAAATTCA
GAAAATGCAGTGCCATAAAATTAAAACAGTCGATATTTCGATTCTTTTGTCAGAAGCTAT
TCGAAGAATACATAACAAAGAATCGATGTCTCATCTTTTCAGAAATGTTACACTTGAGGA
CTAATATCGCACATTGCATATGCTACTTTATATTTTTATAACTGAGTTTTTCCACATTAG
TGCAGAACGGTAATTTTTTTATTCCAATTCAATTCCCTCCTTTCTTCCACGTTAAATTCT
GTGAATTTTTTTCTATGGTTTGTAATGTTGTTAGTCATTCTGTCTTTTATTATCTTGTTT
TGTGTCATTCTGTCTCTTTATTTTTAATCAAAATGGATATTTGCTTGTGTTCGATAAATC
GGACCAAATAAAAGTTAAAAAATTTTATGAAATGAAAATTGTGAAATGACTAAATTAAAA
TATTCTATGATTTTAACAATTTAATAAAAATTTATCAAAAAATATGAAATATAGA
>g2494.t9 Gene=g2494 Length=278
MAYACKTSSAKSIVAVIPYLPYSKQCKMRKRGSIVTKLIAKMMCNAGLTHVITMDLHQKE
IQGFFDCPVDNLRASPFLLQYIQESIPDYRNAVIVARNPGSAKKATSYAERLRLGIAVIH
GEQKDADNDEIDGRNSPPNVPKGRMSDISSGFPSLVAKEKPPINVVGDVGGRIAVIVDDL
IDEVQSFVSAAEVLKERGAYKIYVLATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKM
QCHKIKTVDISILLSEAIRRIHNKESMSHLFRNVTLED
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g2494.t9 | CDD | cd06223 | PRTases_typeI | 74 | 232 | 3.95368E-16 |
| 8 | g2494.t9 | Gene3D | G3DSA:3.40.50.2020 | - | 1 | 77 | 4.5E-24 |
| 7 | g2494.t9 | MobiDBLite | mobidb-lite | consensus disorder prediction | 125 | 145 | - |
| 3 | g2494.t9 | PANTHER | PTHR10210 | RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER | 1 | 276 | 1.0E-148 |
| 4 | g2494.t9 | PANTHER | PTHR10210:SF28 | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 | 1 | 276 | 1.0E-148 |
| 2 | g2494.t9 | Pfam | PF13793 | N-terminal domain of ribose phosphate pyrophosphokinase | 1 | 47 | 5.0E-13 |
| 1 | g2494.t9 | Pfam | PF14572 | Phosphoribosyl synthetase-associated domain | 88 | 272 | 1.2E-99 |
| 5 | g2494.t9 | SUPERFAMILY | SSF53271 | PRTase-like | 1 | 84 | 9.48E-25 |
| 6 | g2494.t9 | SUPERFAMILY | SSF53271 | PRTase-like | 88 | 271 | 4.98E-43 |
| 9 | g2494.t9 | TIGRFAM | TIGR01251 | ribP_PPkin: ribose-phosphate diphosphokinase | 2 | 272 | 2.4E-65 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000287 | magnesium ion binding | MF |
| GO:0004749 | ribose phosphate diphosphokinase activity | MF |
| GO:0009116 | nucleoside metabolic process | BP |
| GO:0009165 | nucleotide biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
