General information for g2532.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Importin-11.
Parent gene
- The parent gene g2532 is located on chr_3: 18493068..18496427 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2532 | g2532.t1 | TSS | g2532.t1 | 18492886 | 18492886 |
| chr_3 | g2532 | g2532.t1 | isoform | g2532.t1 | 18493068 | 18496427 |
| chr_3 | g2532 | g2532.t1 | exon | g2532.t1.exon1 | 18493068 | 18493306 |
| chr_3 | g2532 | g2532.t1 | cds | g2532.t1.CDS1 | 18493068 | 18493306 |
| chr_3 | g2532 | g2532.t1 | exon | g2532.t1.exon2 | 18493598 | 18495483 |
| chr_3 | g2532 | g2532.t1 | cds | g2532.t1.CDS2 | 18493598 | 18495483 |
| chr_3 | g2532 | g2532.t1 | exon | g2532.t1.exon3 | 18495589 | 18496427 |
| chr_3 | g2532 | g2532.t1 | cds | g2532.t1.CDS3 | 18495589 | 18496427 |
| chr_3 | g2532 | g2532.t1 | TTS | g2532.t1 | 18496528 | 18496528 |
Sequences
>g2532.t1 Gene=g2532 Length=2964
ATGAGTCAACAATCGATGGAATTACTTTTCAAAACTCTTAAGCAAGCAACAAATCAACAA
AACCAATCAGAAATTAAGCAAGCAGAAGCAAATTTAGCTGTTTTCGAGAAAGAACCCAAT
TTCTACACTACAGTGTTAGATTTCTATTTAAATGAGCAATTGGATTTGGATGTTCGATAT
ATGAGCTTATTGATTTTGAAACAAGGAATTGATAAATATTGGCGTAAAACACAACAAAAT
TCCATTAAACCAGAGGAAAAAATTTTGTTAAAGAAAAAATTACTCGAGTCATTCAATGAA
AAAATCGATCAATTGGCAGTACAATATGCTGTTATAATATCAAAAATTGCAAGGCTTGAT
TGTCCAGATGATTGGGAAGAGCTCATGCCATTACTTTTACAACGAATCAATACCTCAAAT
GAGCTTGAACAAAAAAGATCTTTGCAAATTCTCGTGCAGGTAGTAAAACAATTATCAACA
AGAAGACTTCATCATGATAGAAAGATTTTTGAACAATTAACTCTCAATTTGTACGAATTT
ATTTGTAATCTATGGAATGGATTTACAATTTTATATTTTCAAAACATCCAAACAAGCGAA
CTTCTTCCAGTGTGCGAAAATAATTTGTGTAAATCAATGCTTGCACTTAAAATAATGCGT
AAATTAACCATTCATGGCTTCCAAAAACCTGCCGAAGCAGCTCAACCACTCGAGTTTCTC
AAAATGATTTTTGAAAGATTAAAAGATCTTCTTGAGTGTCGATTGCTTATAAAATCATCT
CTATATATTACTCTACTCGAAACACACGAAAAATTTATATTAAAGCACATGAAAATTCTA
ACCGAATTCCAAGAATATCATCGAACCGATTTTAATGTTTTTGCACCTCAAGTTTTGGAG
ATGTCATTTAATTTTGTATTTTTTGAAGGAACACGCTTCATTTTTGAAGGTAATCAACTA
ACTATGCCAAATTATGTGATTTCGTGCTTGAACTTGATTAAAGGTTTTCTCCTCAATAAC
GGTGGTAATGTTTATAGCAAGAGCAGCTCTAATGAGACAGATAATAATTTGAATGAAATT
CTTAAGAATTTCTTTACATCTGAAAGGTTAGAGTATATAACAGAAAAATTGCTGATGCAC
TACTTTCTTTTAACGCCAGCTGATTTAGAACTTTGGGAAAACGATCCCGAAGTATTTGTT
TGCGACGAAGGAGGTGATAGTTATAAGTACTCATTACGTTCATGTACAGAAGCATTTTTT
ATGGCTCTATTTCATAAATATAGCAACGTACTCTGCAAGCATTTAAATGTCTATGTACAA
AAATCACAATCAATTGAACTCACATCAACCTCAGATGCTCAGGATATTCTTATCAAAGAA
TCAATATATAATGCAGTTGGATTAGTCACTTTTCATGCATATGATGAAATTGATTTTGAT
AATTGGTTTAAAACTCAACTGTTAAGTGAATTACAGTTAAAAGGAGAAAACTTTAAAATT
CTTCGAAGAAGAATAATTTGGATGATTGGCCAATGGAGTGCTGTTAAATTTTCTAAATCG
TTGCGACCACAATTGTATGAAGCATGTCTTGAACTTTTGCAACCTGTTGAGAATAATGAT
ATGGTAGTTAGATTGACAGCATCGAAAACTTTAAAAAGTGTACTCGAGGATTTTGATTTT
GATGCGGAACAGTTTTTGCCATTTTTAGAGCCATCGTTTACACTTTTATTTCATCTTTTG
AAAGAAGCCAAAGAATGTGATACAAAAATGAATGTTCTTTATGTAATGGCATTTATTGTA
GAAAAAATGTCTCTCTCGATTAAAATACAAGCTGGAAATTTGGTTGCATTTTTACCTGAA
CTTTGGGATGAAGGTGTTGAGCATAATATGCTTCGAATTGCTATAATATCTGCATTAATA
CAAATTATTAAAGCTATACAAGAGATTCCAGAATCTGTCAGTCCATTTATTTATAAAGTC
ATAGAAATTTCTACAAATGTCAACGATCCTTCTACAGTCTACCTTTTAGATGAAGGACTT
GAGTTATGGCTTATAACTATTCAATATGCAATGCAACCAAACGATTCTTTATTACAATTA
TGCAATAATTTGCTTCCAATTATAGAAAAATCTACCCTCAATTTGAGGACATGTCTGTTT
ATAATGCAAGCATACATAATGCTATGTCCGGAAATTTATCTTCAAAGATATGGCAAGGAA
ATTGTGCAACAGTGTCAATATTTGATGAAAGATATCAGAACTGAAGGTGTTGTTACAATT
TGTAAGCTATTTATATCTATGCTGCGAATGCAACCTAATTATGCTATAGAACTTTTACAT
CCTGTTATGATTGACATTGTAAAGAACTTTTTAGATGATAATGATTATTTAACTGTTAAA
CAAATATATCTTCAAGTCATTGTACGATACTTTTTAGCCAATCAAATGGCATTGAATCAT
ATTTTGGAAGAAATTCGAGTAGAAAACGCCTTTCAAAAACTTTTATCAATTTATATTAAT
ACTATGCCAAATGTAACACAAGATGAAGATAAAAAATTGCTTGCTATAGGTCTTTCATGT
CTTTTAACAATTCCTAATCAAATCATACTGGACAATTTCTCAATAATTATAATCAACATT
TATGAAACACTTTGCGATATAATGAAACAATTGAGTGAAGATGGAGAAGAAATTGATGGT
TTAATTTTAAGTGAACATGATGATCTACCGTATGACGAAATTGACGATGTTGAATGGAAA
GCACCACATTATGAAAGATACAAGAGCATGTGTTTAAAAGATTGTGTTCACACTGTGGTT
CTTAAAGAATATTTGCAGAATCAATTGATTGCGCTTAAAAATATTGTTGGTGAAGAGCAA
TATGTAAATTTAATTAAAACTATAGATCCTACAATTCATAAATTGCTTTATAATTATGTT
AATACCATGGTTCCAATTGTTTAA
>g2532.t1 Gene=g2532 Length=987
MSQQSMELLFKTLKQATNQQNQSEIKQAEANLAVFEKEPNFYTTVLDFYLNEQLDLDVRY
MSLLILKQGIDKYWRKTQQNSIKPEEKILLKKKLLESFNEKIDQLAVQYAVIISKIARLD
CPDDWEELMPLLLQRINTSNELEQKRSLQILVQVVKQLSTRRLHHDRKIFEQLTLNLYEF
ICNLWNGFTILYFQNIQTSELLPVCENNLCKSMLALKIMRKLTIHGFQKPAEAAQPLEFL
KMIFERLKDLLECRLLIKSSLYITLLETHEKFILKHMKILTEFQEYHRTDFNVFAPQVLE
MSFNFVFFEGTRFIFEGNQLTMPNYVISCLNLIKGFLLNNGGNVYSKSSSNETDNNLNEI
LKNFFTSERLEYITEKLLMHYFLLTPADLELWENDPEVFVCDEGGDSYKYSLRSCTEAFF
MALFHKYSNVLCKHLNVYVQKSQSIELTSTSDAQDILIKESIYNAVGLVTFHAYDEIDFD
NWFKTQLLSELQLKGENFKILRRRIIWMIGQWSAVKFSKSLRPQLYEACLELLQPVENND
MVVRLTASKTLKSVLEDFDFDAEQFLPFLEPSFTLLFHLLKEAKECDTKMNVLYVMAFIV
EKMSLSIKIQAGNLVAFLPELWDEGVEHNMLRIAIISALIQIIKAIQEIPESVSPFIYKV
IEISTNVNDPSTVYLLDEGLELWLITIQYAMQPNDSLLQLCNNLLPIIEKSTLNLRTCLF
IMQAYIMLCPEIYLQRYGKEIVQQCQYLMKDIRTEGVVTICKLFISMLRMQPNYAIELLH
PVMIDIVKNFLDDNDYLTVKQIYLQVIVRYFLANQMALNHILEEIRVENAFQKLLSIYIN
TMPNVTQDEDKKLLAIGLSCLLTIPNQIILDNFSIIIINIYETLCDIMKQLSEDGEEIDG
LILSEHDDLPYDEIDDVEWKAPHYERYKSMCLKDCVHTVVLKEYLQNQLIALKNIVGEEQ
YVNLIKTIDPTIHKLLYNYVNTMVPIV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g2532.t1 | Coils | Coil | Coil | 18 | 38 | - |
| 6 | g2532.t1 | Gene3D | G3DSA:1.25.10.10 | - | 5 | 983 | 7.5E-139 |
| 2 | g2532.t1 | PANTHER | PTHR10997 | IMPORTIN-7, 8, 11 | 5 | 974 | 5.5E-180 |
| 3 | g2532.t1 | PANTHER | PTHR10997:SF7 | IMPORTIN-11 | 5 | 974 | 5.5E-180 |
| 1 | g2532.t1 | Pfam | PF03810 | Importin-beta N-terminal domain | 28 | 98 | 6.0E-13 |
| 8 | g2532.t1 | ProSiteProfiles | PS50166 | Importin-beta N-terminal domain profile. | 28 | 100 | 17.605 |
| 5 | g2532.t1 | SMART | SM00913 | IBN_N_2 | 28 | 100 | 4.2E-8 |
| 4 | g2532.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 1 | 980 | 2.79E-83 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0031267 | small GTPase binding | MF |
| GO:0006886 | intracellular protein transport | BP |
KEGG
Orthology
- This transcript has been annotated with K25201 (importin-11)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
