General information for g2569.t45
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Homocysteine S-methyltransferase YbgG.
Parent gene
- The parent gene g2569 is located on chr_3: 18787120..18790735 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2569 | g2569.t45 | TTS | g2569.t45 | 18786001 | 18786001 |
| chr_3 | g2569 | g2569.t45 | isoform | g2569.t45 | 18786093 | 18788730 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon1 | 18786093 | 18786265 |
| chr_3 | g2569 | g2569.t45 | cds | g2569.t45.CDS1 | 18786093 | 18786265 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon2 | 18786329 | 18786533 |
| chr_3 | g2569 | g2569.t45 | cds | g2569.t45.CDS2 | 18786329 | 18786533 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon3 | 18786923 | 18787000 |
| chr_3 | g2569 | g2569.t45 | cds | g2569.t45.CDS3 | 18786923 | 18787000 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon4 | 18787056 | 18787204 |
| chr_3 | g2569 | g2569.t45 | cds | g2569.t45.CDS4 | 18787056 | 18787204 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon5 | 18787332 | 18787608 |
| chr_3 | g2569 | g2569.t45 | cds | g2569.t45.CDS5 | 18787332 | 18787608 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon6 | 18787730 | 18787859 |
| chr_3 | g2569 | g2569.t45 | cds | g2569.t45.CDS6 | 18787730 | 18787780 |
| chr_3 | g2569 | g2569.t45 | exon | g2569.t45.exon7 | 18788651 | 18788730 |
| chr_3 | g2569 | g2569.t45 | TSS | g2569.t45 | 18788728 | 18788728 |
Sequences
>g2569.t45 Gene=g2569 Length=1092
TAGTACTGTGTAGAATCTCTAATAATCAACTTCAAACATCATTAAAAGGAGACATTTTCG
GAAGAAAAAAAGTCTTAAAGATTAAAACCTGACCTGCAAAACGAGGAGAAAAAATAATGT
CAGACGAGTCACAACAACAACAACATATAACAGTCATTGATGGTGGATTTTCAACTCAAC
TTAGTTTTCATGTCGGTGAAAATATCGATGATTACCTTTTTTATTTTTAGATTTAATGCA
GTTAATCCCGAAGCTGTCATTCAAAGTCATTTAGATTTTCTTAATGCAGGAGCTGAAATA
ATTTTGACAAACACCTATCAAGCTAGTATTGAAGGATATCAAACTTATTTGGATCTAGAT
TATCATGGAAGTTATGAGCTTATTAAGTCAACAGTGAAGCTAGCTCATATTGCGCGTGAC
AAATTTTTATCTTCGCATATCAACCATGTGAAAAAACCTTTAATTTTTGCATCAATCGGT
CCTTATGGTGCGCATTTACATGATGGAAGTGAATATACTGGAAGTTATGAAAAAAGAGTG
TCACCTGCAGCAATCAAAAAATGGCACAAAGTGAGAATCGATGCATGTGTTGAATCGGGG
GTTGATGGATTAGCAATTGAAACTATTCCATGTTTGATGGAAGCAAATGCATTAGTTGAT
CTCGTTCTCACGGAATATCCAAATTTAAAATTTTGGATATCTTTCCAATGCAAGAACGGT
GAAGTAATTGCTAATGGACAAAGATTTTCTGACTGCATTTTATCTATTTGGAATCAAGTA
GAAGCAGCTAAACGTCCAGAAAATTTAGTTGCAGTTGGAATTAATTGTATAAATCCAAGC
TTTGTTTCACCACTTTTTTCTGAAATTGAGAAAAATTTGTGCAATTTCAATGTACCGCTA
GTCGTGTACCCAAACAGTGGTGAAGTTTATACTGTTGAAGAAGGTTGGCATGGGAAAAAT
GACTGCATTCCATTAGAGAATTATATTGAAGAATGGGTCAAATTAGGAGCAAAATATATT
GGAGGATGTTGTCGTACAAATGCTCATGATATTGAGAAAATCAAAAATAAAATTGAGGCT
CTAAAAAATTAA
>g2569.t45 Gene=g2569 Length=310
MVDFQLNLVFMSVKISMITFFIFRFNAVNPEAVIQSHLDFLNAGAEIILTNTYQASIEGY
QTYLDLDYHGSYELIKSTVKLAHIARDKFLSSHINHVKKPLIFASIGPYGAHLHDGSEYT
GSYEKRVSPAAIKKWHKVRIDACVESGVDGLAIETIPCLMEANALVDLVLTEYPNLKFWI
SFQCKNGEVIANGQRFSDCILSIWNQVEAAKRPENLVAVGINCINPSFVSPLFSEIEKNL
CNFNVPLVVYPNSGEVYTVEEGWHGKNDCIPLENYIEEWVKLGAKYIGGCCRTNAHDIEK
IKNKIEALKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g2569.t45 | Coils | Coil | Coil | 291 | 310 | - |
| 5 | g2569.t45 | Gene3D | G3DSA:3.20.20.330 | - | 20 | 305 | 4.3E-81 |
| 2 | g2569.t45 | PANTHER | PTHR46015 | ZGC:172121 | 20 | 307 | 2.5E-83 |
| 3 | g2569.t45 | PANTHER | PTHR46015:SF1 | ZGC:172121 | 20 | 307 | 2.5E-83 |
| 10 | g2569.t45 | PIRSF | PIRSF037505 | BHMT | 23 | 177 | 5.4E-4 |
| 11 | g2569.t45 | PIRSF | PIRSF037505 | BHMT | 257 | 309 | 0.0078 |
| 1 | g2569.t45 | Pfam | PF02574 | Homocysteine S-methyltransferase | 28 | 304 | 9.7E-61 |
| 8 | g2569.t45 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 9 | g2569.t45 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 25 | - |
| 7 | g2569.t45 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 26 | 310 | - |
| 12 | g2569.t45 | ProSiteProfiles | PS50970 | Homocysteine-binding domain profile. | 1 | 305 | 36.275 |
| 4 | g2569.t45 | SUPERFAMILY | SSF82282 | Homocysteine S-methyltransferase | 21 | 307 | 5.49E-64 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008270 | zinc ion binding | MF |
| GO:0047150 | betaine-homocysteine S-methyltransferase activity | MF |
| GO:0009086 | methionine biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed