General information for g2619.t21
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphoglycerate mutase 2.
Parent gene
- The parent gene g2619 is located on chr_3: 19148907..19150306 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2619 | g2619.t21 | TTS | g2619.t21 | 19148691 | 19148691 |
| chr_3 | g2619 | g2619.t21 | isoform | g2619.t21 | 19148907 | 19150306 |
| chr_3 | g2619 | g2619.t21 | exon | g2619.t21.exon1 | 19148907 | 19149073 |
| chr_3 | g2619 | g2619.t21 | cds | g2619.t21.CDS1 | 19148907 | 19149073 |
| chr_3 | g2619 | g2619.t21 | exon | g2619.t21.exon2 | 19149133 | 19149751 |
| chr_3 | g2619 | g2619.t21 | cds | g2619.t21.CDS2 | 19149133 | 19149730 |
| chr_3 | g2619 | g2619.t21 | exon | g2619.t21.exon3 | 19149936 | 19150306 |
| chr_3 | g2619 | g2619.t21 | TSS | g2619.t21 | NA | NA |
Sequences
>g2619.t21 Gene=g2619 Length=1157
TAAGATCAATTTTTATGACAATTGAAATTTAAGCGCAAAAAGTATATTTTTGATGAAACT
CTTTTCTCAAACTTATTTTTACTTGTACTTAAGTCTTGTTCGATAATATATAATAAGGTA
ATTGATATTGAGCAGTTTATGAATTAATTTTATAAGCTTAACTACCTAATTTTTAATTTT
TTGAAACTTTTACTTCTTTAAATATAAGAATATTTATAAACATAAACATGACGAATATTT
AACGAAAAATTCATGTGACGGAACTTTTAACAAAAAAAATTCTGCCCCAAAACGAACTTG
AAAGGTCAAATATTTTCCTACTGCTTAATTTTTCAGCAAAAATTCGGCATTTCTCAAGTT
TCTTTCATCGAGTGTCATCAATTGTATCAAAAATGGCAAAGTATCAAATTGTTATGGTCA
GACATGGTGAGAGTGAGTGGAATCAACTCAATTTGTTTTGCGGTTGGTTCAATGCTGACT
TAAGTGATAAGGGTCGACAAGAGGCAATTGACGCAGGAAAGGCTATTAAAGAAGCTGGTC
TCAAGTTTGATATCGCTCATACATCAGTTTTGAAGCGTGCAAATTTGACACTCGACTCAA
TCCTTAAAGAATCTGGTCAAACTGGAATTCCCATTTACAAGACATGGCGTTTAAATGAAC
GTCACTATGGTGGTTTGACTGGCATGAATAAGGCTGAGACTGCTGAAAAGTATGGTGAGG
AACAAGTTAAGATCTGGCGTCGATCTTACGATATTCCACCACCACCAATGGAAGAAGATC
ATAAATATTATAAAACAATTGTCGAAGATCCAATCTATGCTGATGGTCCCTCAAAAGATG
AATTCCCTAAATTCGAGTCTTTGAAACTTACTATTCAGCGAACACTCCCATATTGGAATG
AGACCATTATTCCTCAATTGAAGGAAGGCAAGAAAATTATTATTGCTGCTCACGGTAACA
GCTTGAGAGGCATTGTTAAACATCTTGATCAAATGTCTGATGAGGCTATTATGGGTTTGA
ATTTGCCAACTGGAATTCCATTTGTTTATGAGCTGGATGAGAACTTCAAACCAGTTGTCT
CAATGAAATTCTTGGGTGATGAAGAAACAGTAAGAAAAGCTATGGAGAGCGTTGCCAACC
AAGGCAAAGCTAAGTAA
>g2619.t21 Gene=g2619 Length=254
MAKYQIVMVRHGESEWNQLNLFCGWFNADLSDKGRQEAIDAGKAIKEAGLKFDIAHTSVL
KRANLTLDSILKESGQTGIPIYKTWRLNERHYGGLTGMNKAETAEKYGEEQVKIWRRSYD
IPPPPMEEDHKYYKTIVEDPIYADGPSKDEFPKFESLKLTIQRTLPYWNETIIPQLKEGK
KIIIAAHGNSLRGIVKHLDQMSDEAIMGLNLPTGIPFVYELDENFKPVVSMKFLGDEETV
RKAMESVANQGKAK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g2619.t21 | CDD | cd07067 | HP_PGM_like | 5 | 229 | 2.98563E-45 |
| 6 | g2619.t21 | Gene3D | G3DSA:3.40.50.1240 | - | 1 | 254 | 1.3E-84 |
| 4 | g2619.t21 | Hamap | MF_01039 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. | 3 | 234 | 41.557571 |
| 2 | g2619.t21 | PANTHER | PTHR11931:SF8 | PHOSPHOGLYCERATE MUTASE 2 | 2 | 254 | 7.2E-120 |
| 3 | g2619.t21 | PANTHER | PTHR11931 | PHOSPHOGLYCERATE MUTASE | 2 | 254 | 7.2E-120 |
| 7 | g2619.t21 | PIRSF | PIRSF000709 | 6PFK_fruc_bisph_Ptase | 1 | 119 | 1.2E-7 |
| 8 | g2619.t21 | PIRSF | PIRSF000709 | 6PFK_fruc_bisph_Ptase | 170 | 242 | 59.0 |
| 1 | g2619.t21 | Pfam | PF00300 | Histidine phosphatase superfamily (branch 1) | 6 | 129 | 1.4E-25 |
| 10 | g2619.t21 | ProSitePatterns | PS00175 | Phosphoglycerate mutase family phosphohistidine signature. | 8 | 17 | - |
| 11 | g2619.t21 | SMART | SM00855 | PGAM_5 | 5 | 194 | 1.9E-18 |
| 5 | g2619.t21 | SUPERFAMILY | SSF53254 | Phosphoglycerate mutase-like | 4 | 243 | 1.11E-72 |
| 12 | g2619.t21 | TIGRFAM | TIGR01258 | pgm_1: phosphoglycerate mutase 1 family | 5 | 252 | 6.8E-112 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004619 | phosphoglycerate mutase activity | MF |
| GO:0006096 | glycolytic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0016868 | intramolecular transferase activity, phosphotransferases | MF |
KEGG
Orthology
- This transcript has been annotated with K01834 (2,3-bisphosphoglycerate-dependent phosphoglycerate mutase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
