General information for g2632.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Multidrug resistance-associated protein 4.
Parent gene
- The parent gene g2632 is located on chr_3: 19194342..19195696 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2632 | g2632.t1 | isoform | g2632.t1 | 19194342 | 19195696 |
| chr_3 | g2632 | g2632.t1 | exon | g2632.t1.exon1 | 19194342 | 19194670 |
| chr_3 | g2632 | g2632.t1 | cds | g2632.t1.CDS1 | 19194342 | 19194670 |
| chr_3 | g2632 | g2632.t1 | exon | g2632.t1.exon2 | 19194901 | 19195123 |
| chr_3 | g2632 | g2632.t1 | cds | g2632.t1.CDS2 | 19194901 | 19195123 |
| chr_3 | g2632 | g2632.t1 | exon | g2632.t1.exon3 | 19195184 | 19195696 |
| chr_3 | g2632 | g2632.t1 | cds | g2632.t1.CDS3 | 19195184 | 19195696 |
| chr_3 | g2632 | g2632.t1 | TSS | g2632.t1 | NA | NA |
| chr_3 | g2632 | g2632.t1 | TTS | g2632.t1 | NA | NA |
Sequences
>g2632.t1 Gene=g2632 Length=1065
ATGAATTCACAAAATTCAAAACAAAAGCCAGAAAATCCTCTACAGAATGCATCTCGATTG
AGCAGAATGACATTTTGGTGGCTTAAAGATCTGTATAAAATTGGTATGACACGACCAATT
ACGGACGATGATGTTTATCAGACAATTGACCATCATGAATGTGATCGAATAGCAAACAAA
TTTAAAACGTTATGGCAGAAGGAACTTGATGGATCAAAAAGACCAAGTGCACTTAGATTA
ATTTACAATGCTTATGGACCGCCTGTACTGATAATTGGATTACTTTTCTCGGTCTGTGAA
ACGTTGATGCGTTGTGCACAGCCGTTGTTGCTAGGTGAACTTCTTACTTATTTTGCTGAT
GAAAGTGCATCGAAAGAATGGGCATATATTTACGCAGCAGGAATTGTTATATGCTCGATT
GTTCCTGTAATAACATTCCATCCATTTATCTATTACATTTTTGAAATTGGAATGAAAATA
AGAATTGGCTGCTCAAGATTAGTTTATGATAAGATTCTTCGAATAACAAAATCAGTACAA
GAAGATGGAATGCATGGAAAAGTGATAAATTTACTATCAAATGATTTCTCAAAATTTGAT
ATTGCACTTGCATTCTTGCATGATCTTTGGAAGGGACCATTTGAGACAATTCTTCTAGGA
TTTTTAATTTATCGTGAAGTCGGAATTTCTGGTGTTTTTGGAATCTTGTTTATTCTCTCG
TTCATTCCAATACAATCTTATATTGGTAAAAAGGCTGCACATTTTCGAAATCAAACAACT
AAACGAACGGACATTCGTGTTCGATTGATGAACGAAATTATCAATGGCATACAGGTGATC
AAAATGTATTCATGGCAACAAAATTTTGCAAAAGTTATTGAAAAAGTTCGTAGGAAAGAG
ATTGCAGCTGTTAAAGGCAGTAGTTATATTCTAGCGTTGCTGTATACGCTTTGGGCAGTT
TCACGTGTTTCTCTGTTTCTAACGCTGATAACGTTTGTGTACTCTGGCAATGTGCTTACT
GCTCGTAAAGTCGTTAACAGTTTTTATCGTCACAGCATTTTATAA
>g2632.t1 Gene=g2632 Length=354
MNSQNSKQKPENPLQNASRLSRMTFWWLKDLYKIGMTRPITDDDVYQTIDHHECDRIANK
FKTLWQKELDGSKRPSALRLIYNAYGPPVLIIGLLFSVCETLMRCAQPLLLGELLTYFAD
ESASKEWAYIYAAGIVICSIVPVITFHPFIYYIFEIGMKIRIGCSRLVYDKILRITKSVQ
EDGMHGKVINLLSNDFSKFDIALAFLHDLWKGPFETILLGFLIYREVGISGVFGILFILS
FIPIQSYIGKKAAHFRNQTTKRTDIRVRLMNEIINGIQVIKMYSWQQNFAKVIEKVRRKE
IAAVKGSSYILALLYTLWAVSRVSLFLTLITFVYSGNVLTARKVVNSFYRHSIL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g2632.t1 | Gene3D | G3DSA:1.20.1560.10 | - | 85 | 346 | 6.1E-16 |
| 2 | g2632.t1 | PANTHER | PTHR24223 | ATP-BINDING CASSETTE SUB-FAMILY C | 3 | 350 | 1.2E-112 |
| 3 | g2632.t1 | PANTHER | PTHR24223:SF324 | LD17001P | 3 | 350 | 1.2E-112 |
| 1 | g2632.t1 | Pfam | PF00664 | ABC transporter transmembrane region | 90 | 334 | 1.6E-22 |
| 12 | g2632.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 88 | - |
| 18 | g2632.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 89 | 110 | - |
| 14 | g2632.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 111 | 129 | - |
| 17 | g2632.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 130 | 154 | - |
| 13 | g2632.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 155 | 226 | - |
| 16 | g2632.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 227 | 248 | - |
| 15 | g2632.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 249 | 308 | - |
| 19 | g2632.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 309 | 334 | - |
| 11 | g2632.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 335 | 354 | - |
| 10 | g2632.t1 | ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 91 | 341 | 26.123 |
| 8 | g2632.t1 | SUPERFAMILY | SSF90123 | ABC transporter transmembrane region | 86 | 337 | 6.8E-27 |
| 5 | g2632.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 80 | 102 | - |
| 7 | g2632.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 129 | 151 | - |
| 4 | g2632.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 227 | 249 | - |
| 6 | g2632.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 318 | 340 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
