General information for g2634.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein lethal(2) giant larvae.
Parent gene
- The parent gene g2634 is located on chr_3: 19210865..19211938 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2634 | g2634.t1 | isoform | g2634.t1 | 19205962 | 19211268 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon1 | 19205962 | 19206048 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS1 | 19205962 | 19206048 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon2 | 19207539 | 19209615 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS2 | 19207539 | 19209615 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon3 | 19209679 | 19209875 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS3 | 19209679 | 19209875 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon4 | 19209932 | 19210077 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS4 | 19209932 | 19210077 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon5 | 19210205 | 19210474 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS5 | 19210205 | 19210474 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon6 | 19210531 | 19210796 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS6 | 19210531 | 19210796 |
| chr_3 | g2634 | g2634.t1 | exon | g2634.t1.exon7 | 19210865 | 19211268 |
| chr_3 | g2634 | g2634.t1 | cds | g2634.t1.CDS7 | 19210865 | 19211268 |
| chr_3 | g2634 | g2634.t1 | TTS | g2634.t1 | 19211935 | 19211935 |
| chr_3 | g2634 | g2634.t1 | TSS | g2634.t1 | NA | NA |
Sequences
>g2634.t1 Gene=g2634 Length=3447
ATGCTAAAATTTATTCGATCGAAAGGACATCAGCAACCATCAGCTGAACGTCAAAAATTG
CAAAAGGAATTATATGCATTTCGTAAGACGGTACAACATGGATTTCCACACAAACCGTCT
TCGCTTGCTTATGATTCTGTTTTGAAATTAATGGCTATCGGCACAACTGTCGGTGTCATT
AAGGTGTTTGGTCAGCCAGGTGTGGAATTTTATGGACAAACAACGCCAATCATCACATCT
ACAAATCCCAGCCCAACTGATTGTACAGTTCAAATTCTTGAATTCATTCCTGGAAATGGT
CGATTGCTTTCATTGACATCAAATAATCAATTGACACTTTGGGAACCAGCTGGTACACTT
TTAGTTGCCATCAAGACACTTGCTTTGGAGAAATTTAAAAAAGTTTCAACTTTATGTTGT
TCTTATATTAAAGATTTGCTTTGGATTGGAACAGAAGGTGGAAATGTCTATCAATTTGAT
CTCAAGACTTTCCAAATCAAAGAATCGACAATCTTTCATGATGCAGTCTATGATCAGTTG
CCAGCCAGTTATAAACTTAATCCTGGCGCCATCGAATCAATAAAGCAGTTGCCTGAGCAG
CCTCACTTGCTTCTTATTGCATACAATCGTGGTCTTGCCGTTTTGTGGGATTTGGAAGAG
AGCAAAGTTGTTCGCAGCTATATTTCACCAGGTCATGGCATGAGCGTAGGAATTTACGTG
GATCAAATTGGAAATAAATTTACATGGTATCACGCTGATGGATCATATGCAACTTGGGAC
ATTGAAAGCACAAATGAACCCGAAAATGTCAAGTACGTTCCATATGGACCTGATCCATGC
AAAGCAATTGATCGCCTTGTCCGTGGTTTTCGCGGTGACAATGAACTAATTATTTTCTCA
GGCGGAATGCCGCGATCAGCTTACGGTGATCATCAATGCGTTTCAGTGCATTGCAAAGAT
GGATCGAAAATTGCACTCGATTTCACATCAAAAGTAATTGACTTTTTTGTGACATTTAAA
GATATCGAAAGTGCAAATGAAAAACCACAAGCTGAAGTATTGATTGTATTATTAGAAGAA
GAATTGGTTGCTTATGATTTAACACAAAAATCTCTTCCACTTATAAACGCTCCATATTTG
CATTCACTTCATGCTTCTGCAGTTACTTGCAATCATTTGGTATCACAAGTCACAGCAGAA
GTTTATGATAAAATTGTTCAGGCTGGCATTCATCAGTATACGAAATACAGTGACATCACA
TGGCCAATTAATGGCGGAGAAGTTCCAGAGCGTGCAAATGATTCAAATGTAAATGAATAT
GACATTCTTTTAACAGGTCATGAAGACGGTTCTGTAAAATTCTGGGACTGCTCTGACATT
TGTCTAACACCACTATTGCATGTGAAAACAGCTCATCTTTTTGGCAATAGTGATGATTTG
GATCAACCAAGAGACGATGATGAACCATTAGAAGACGACGATGAACCGCCTTTCAGAAAA
GCTGGACAATTTGATCCTTACAGTGATGATCCACGTTTAGCTGTCAAGAAAATTTCATTA
TGTCCGAGGACTGGTGTTTTGATAATTGCTGGAACGGCTGGAAATATTGTTGTAGCTTCT
ATTGATGATGCATCTTCAGAAAGTACAGAAGGAATAAAAACAACAACAATGGATTTAGTT
AGTGAGCATCTTGGATTTGTTTGGAAAGGTCATGATCCATTGAAAGTTAAAAAGCAACTT
TTGGAACAGAGTCAACCATTGACTGAAGGTGTTGATGTACTTGGAGTGTTGCAAATTAAA
CCACCAGCAGCAATTACTTGCTTGGCATTACAAACTAAATGGGGATTACTCTCAGCTGGC
ACTGCTCATGGTCTCGTTTTATATGATTTTAAAAACAATCGACCTGTACTTCATAAATGC
ACTTTAAATCCAAACGACTTGACTGGTGCTGGTGAACAAATTTCGAGAAGAAAATCATTT
AAAAAATCTTTGCGTGAATCATTCAGACGTCTTCGCAAGGGAAGATCGACTAGAAATAAT
AATCAACCTAATATACCAGCCGAAACGAGGCCTGTTGAGCGACAGATTGAAGCACGTGCT
GTCGATGACGGCATGGGCTCAATGATCCGTTGTCTCACATTTGCGCAGACTTATATTACC
AATGTTAATGCCGCTGTTCCAACTTTATGGTCGGGAACAAATTCGAGTTGTGTTTCAATC
TTTATTCTTCACATTCCACAAACTTCTGGAGCAGCTACACTAACACCAGGCGAAGCACCG
CGTCCAATTATGGGTCAATTGGCTAAAGAAATACAAATCAAGCATAGAGCACCTGTAATT
GCTATCTCACTGTTTGATGCTAACAATGTACCTTTGGATTTCCAAGATGGTCCAGGAGTT
GGTACGCACAAAGTGGTTATTGCATCAGAAGAACAGTTCAAACTTTTTTCATTACCACAA
TTGAAGCCTATTAATAAATATAAATTGACTGCACATGAAGGTGCTCGTGTAAGAAGAATG
CAATTTGGTGCATTTACATGCTCAGTTTCACCTGATCAATTAGTTATGAGTCCACAAAAA
GGACAAAGACCAGCTTCACCACTTGCAGCTCAACCAGCTAGCGATAATACCGATGCAGCA
GCACCGACAGTTGAGAATGTTTTATACAAGGAATATGGATTATTGTGCCTTACCAATTTG
GGCGATGTTCTTGTTTTATCCATTCCAGAATTTAAACGACAACTTAATGCAGCAGTTATT
CGAAGAGAAGATATCAATGGAATTTCTTCATTATGTTTCACAAATCATGGTGAAGCATTA
TATATGCTATCATCGTCGGAAGTACAACGAGTTACATTGTCAGCAACTAAAATTGTTTCT
CCTAATGGAGCAATTGATTTAGAAGAATGGGATGATGATCGTGAATCAGAATCAGTTGAT
GCCGATAACAACCTAGAGACAGAAGAGGGAAATGAAAATACAACGATTGAGGCAACAACA
CCAATTAGTGCAGCTCATAGCGATATTGCTGTAAATAAAACTGAACATTTGACGAATGGA
GTTGATTCCTCACCAAATAGTGTAAACAATAATAACAATGAAACACTCACCAGTTCAATG
GGTGACATCACAATAGATTCTGTACGAGATCATTTAAATTCGACAGTTACAACACTCTGC
TCAACAACGACAGAAGAAATTGTTGGCCGCTTATCAGTGCTATCGACGTCAATCAATAAT
ACAACAACCAGTTTGAATCCGAAAGAAATTTTGGATATAAAGACACTGAAGGATACAGAC
GTAGGCGGAGAAACAAATGAAACGCACCAGAATTCAGTCGTTGTGAAATCGTTTATAACG
ACTATTTCGCACGGCACTGGTGCGACTAATGGCGAGACCGAAAAAACTACAACAACAACA
TACACCCGAAAGGAGAGCGCATTTTAA
>g2634.t1 Gene=g2634 Length=1148
MLKFIRSKGHQQPSAERQKLQKELYAFRKTVQHGFPHKPSSLAYDSVLKLMAIGTTVGVI
KVFGQPGVEFYGQTTPIITSTNPSPTDCTVQILEFIPGNGRLLSLTSNNQLTLWEPAGTL
LVAIKTLALEKFKKVSTLCCSYIKDLLWIGTEGGNVYQFDLKTFQIKESTIFHDAVYDQL
PASYKLNPGAIESIKQLPEQPHLLLIAYNRGLAVLWDLEESKVVRSYISPGHGMSVGIYV
DQIGNKFTWYHADGSYATWDIESTNEPENVKYVPYGPDPCKAIDRLVRGFRGDNELIIFS
GGMPRSAYGDHQCVSVHCKDGSKIALDFTSKVIDFFVTFKDIESANEKPQAEVLIVLLEE
ELVAYDLTQKSLPLINAPYLHSLHASAVTCNHLVSQVTAEVYDKIVQAGIHQYTKYSDIT
WPINGGEVPERANDSNVNEYDILLTGHEDGSVKFWDCSDICLTPLLHVKTAHLFGNSDDL
DQPRDDDEPLEDDDEPPFRKAGQFDPYSDDPRLAVKKISLCPRTGVLIIAGTAGNIVVAS
IDDASSESTEGIKTTTMDLVSEHLGFVWKGHDPLKVKKQLLEQSQPLTEGVDVLGVLQIK
PPAAITCLALQTKWGLLSAGTAHGLVLYDFKNNRPVLHKCTLNPNDLTGAGEQISRRKSF
KKSLRESFRRLRKGRSTRNNNQPNIPAETRPVERQIEARAVDDGMGSMIRCLTFAQTYIT
NVNAAVPTLWSGTNSSCVSIFILHIPQTSGAATLTPGEAPRPIMGQLAKEIQIKHRAPVI
AISLFDANNVPLDFQDGPGVGTHKVVIASEEQFKLFSLPQLKPINKYKLTAHEGARVRRM
QFGAFTCSVSPDQLVMSPQKGQRPASPLAAQPASDNTDAAAPTVENVLYKEYGLLCLTNL
GDVLVLSIPEFKRQLNAAVIRREDINGISSLCFTNHGEALYMLSSSEVQRVTLSATKIVS
PNGAIDLEEWDDDRESESVDADNNLETEEGNENTTIEATTPISAAHSDIAVNKTEHLTNG
VDSSPNSVNNNNNETLTSSMGDITIDSVRDHLNSTVTTLCSTTTEEIVGRLSVLSTSINN
TTTSLNPKEILDIKTLKDTDVGGETNETHQNSVVVKSFITTISHGTGATNGETEKTTTTT
YTRKESAF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g2634.t1 | Gene3D | G3DSA:2.130.10.10 | - | 19 | 302 | 5.4E-12 |
| 18 | g2634.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 477 | 503 | - |
| 17 | g2634.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 856 | 877 | - |
| 15 | g2634.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 970 | 996 | - |
| 16 | g2634.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 970 | 987 | - |
| 2 | g2634.t1 | PANTHER | PTHR10241 | LETHAL 2 GIANT LARVAE PROTEIN | 8 | 1082 | 0.0 |
| 3 | g2634.t1 | PANTHER | PTHR10241:SF29 | LETHAL(2) GIANT LARVAE PROTEIN | 8 | 1082 | 0.0 |
| 4 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 19 | 37 | 9.6E-85 |
| 9 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 295 | 317 | 9.6E-85 |
| 12 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 349 | 369 | 9.6E-85 |
| 5 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 440 | 463 | 9.6E-85 |
| 6 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 523 | 541 | 9.6E-85 |
| 8 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 562 | 581 | 9.6E-85 |
| 7 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 607 | 631 | 9.6E-85 |
| 10 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 637 | 656 | 9.6E-85 |
| 11 | g2634.t1 | PRINTS | PR00962 | Lethal(2) giant larvae protein signature | 688 | 707 | 9.6E-85 |
| 1 | g2634.t1 | Pfam | PF08366 | LLGL2 | 272 | 373 | 3.1E-29 |
| 14 | g2634.t1 | SUPERFAMILY | SSF50978 | WD40 repeat-like | 29 | 538 | 1.02E-21 |
| 13 | g2634.t1 | SUPERFAMILY | SSF50978 | WD40 repeat-like | 442 | 938 | 8.85E-8 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K06094 (lethal(2) giant larvae protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
