General information for g2663.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose-6-phosphate isomerase.
Parent gene
- The parent gene g2663 is located on chr_3: 19453861..19455290 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2663 | g2663.t1 | TTS | g2663.t1 | 19450762 | 19450762 |
| chr_3 | g2663 | g2663.t1 | isoform | g2663.t1 | 19450968 | 19453861 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon1 | 19450968 | 19451438 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS1 | 19450968 | 19451438 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon2 | 19451516 | 19451566 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS2 | 19451516 | 19451566 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon3 | 19451704 | 19451716 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS3 | 19451704 | 19451716 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon4 | 19451785 | 19451966 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS4 | 19451785 | 19451966 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon5 | 19452025 | 19452185 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS5 | 19452025 | 19452185 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon6 | 19452244 | 19452865 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS6 | 19452244 | 19452865 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon7 | 19452950 | 19453133 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS7 | 19452950 | 19453133 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon8 | 19453705 | 19453719 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS8 | 19453705 | 19453719 |
| chr_3 | g2663 | g2663.t1 | exon | g2663.t1.exon9 | 19453815 | 19453861 |
| chr_3 | g2663 | g2663.t1 | cds | g2663.t1.CDS9 | 19453815 | 19453861 |
| chr_3 | g2663 | g2663.t1 | TSS | g2663.t1 | NA | NA |
Sequences
>g2663.t1 Gene=g2663 Length=1746
ATGTCTTATAATGTCGGTATAGAAGAGACTCTACTGACAGCAATGCTTGATAAATTTTTA
AAGTCTATTAAACCGAAAATGTCGAAGCCTCTTCTTACAACCGATCCTGTTTATCAAAAA
CTTCAACAATATTACAATGAAAACGGGGCAAAAATAAACATCAAACAATTATTTGATAGT
GATCCAAAACGTTTCGATAAGTTTAGCTTGACTTTAAAAACACCAAATGACGGTGATATT
TTGCTGGATTACTCGAAAAATCGTATTACTGATGACGTGTGGAAGCTGTTGTTGCAACTT
GCTGAGTCTCGTGGCTTGCAACAAGCTCGCACTCAAATGTTCAGTGGAGAACACATCAAT
ATAACTGAAGACCGTGCTGTTTTGCATACGGCATTGCGTAATAAATCTGGCAAACCGGTT
CTTGTTGATGGCAAGGATGTTATGCCAGAAATTAATGCTGTGTTAGAGCACATGAAGGAA
TTTACAAACCAAGTTGTTAGTGGTGAATGGAAAGGCTATACTGGAAAGAAAATTACTGAC
GTGGTTAATATCGGTATTGGCGGAAGCGATCTCGGTCCTTTGATGGTCACTGAAGCTCTC
AAACCTTATTCAACTGGTTTGAAAATGCATTTTGTATCAAATATTGATGGTACACATTTA
GCTGAAACACTTAAAAAGATTTCTGCCGAGACAACACTTTTTATTATTGCGTCAAAAACG
TTCACTACACAGGAAACAATTACTAACGCTACATCAGCAAAAACATGGTTCTTGGATGTT
GCTAAAGATCCAAGTGCAGTAGCCAAGCATTTCGTTGCATTATCAACAAATGAAGAAAAA
GCAACAGCATTTGGAATTGACGCAAAAAATATGTTTGCATTCTGGGACTTTGTTGGTGGT
CGTTATAGCTTGTGGTCTGCTATTGGCTTATCAATTTCGCTCTCTATTGGCTTTGAAAAT
TTTGTTAAACTTCAAGAAGGAGCATTCTTTATTGATCAACACTTTCAAACAGCTCCATTA
GAACAAAATGCACCAGTCATTCTTGCATTATTGGGTATTTGGTATTCTAACTTTTATGGC
GCAGAGACAACAGCTCTTTTACCATATGATCAATATTTGCATCGTTTTGCTGCCTACTTC
CAGCAAGGTGATATGGAAAGTAATGGTAAAGGTGTTACAAAGAGCGGCAAGCATGTTGAT
TACAACACTGGACCTATCGTTTGGGGCGAGCCAGGAACAAATGGACAACATGCATTCTAT
CAATTGATCCATCAGGGAACTCGTTTGATTCCATGTGACTTTATTGCTCCTGCTCAAACT
CAAAATCCTATTGCTGGAGGTATTCATCATAAATTGATTCTTGCCAACTTTTTGGCACAA
ACTGAGGCTCTCATGTGCGGTAAGACCGAACAACAAGTCAGAGCTGAATTGGAAAAAGCT
GGTATGAAAGGAGAAAAATTAGAGAATCTTGTTCCACATAAAATCTTTACTGGAAATCGC
CCAACTAACTCAATTGTTGTGAAGAAAGTTACACCATTCACTCTTGGTGCTCTCATTGCA
ATGTATGAGCACAAAATCTTCACACAAGGCATCATTTGGGACGTTAATTCATTTGATCAA
TGGGGTGTTGAACTTGGAAAAGCATTGGCAAAGGCAATTGAAGGTGATTTGGCAAACAAT
GACAAAGTTTCAAGTCATGATGCATCAACAAACGGCTTGATTAATTTTATCAAATCTAGC
TGGTAA
>g2663.t1 Gene=g2663 Length=581
MSYNVGIEETLLTAMLDKFLKSIKPKMSKPLLTTDPVYQKLQQYYNENGAKINIKQLFDS
DPKRFDKFSLTLKTPNDGDILLDYSKNRITDDVWKLLLQLAESRGLQQARTQMFSGEHIN
ITEDRAVLHTALRNKSGKPVLVDGKDVMPEINAVLEHMKEFTNQVVSGEWKGYTGKKITD
VVNIGIGGSDLGPLMVTEALKPYSTGLKMHFVSNIDGTHLAETLKKISAETTLFIIASKT
FTTQETITNATSAKTWFLDVAKDPSAVAKHFVALSTNEEKATAFGIDAKNMFAFWDFVGG
RYSLWSAIGLSISLSIGFENFVKLQEGAFFIDQHFQTAPLEQNAPVILALLGIWYSNFYG
AETTALLPYDQYLHRFAAYFQQGDMESNGKGVTKSGKHVDYNTGPIVWGEPGTNGQHAFY
QLIHQGTRLIPCDFIAPAQTQNPIAGGIHHKLILANFLAQTEALMCGKTEQQVRAELEKA
GMKGEKLENLVPHKIFTGNRPTNSIVVKKVTPFTLGALIAMYEHKIFTQGIIWDVNSFDQ
WGVELGKALAKAIEGDLANNDKVSSHDASTNGLINFIKSSW
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g2663.t1 | CDD | cd05015 | SIS_PGI_1 | 152 | 314 | 1.85662E-74 |
| 17 | g2663.t1 | CDD | cd05016 | SIS_PGI_2 | 362 | 553 | 3.57573E-88 |
| 14 | g2663.t1 | Gene3D | G3DSA:3.40.50.10490 | - | 31 | 132 | 6.5E-33 |
| 13 | g2663.t1 | Gene3D | G3DSA:3.40.50.10490 | - | 133 | 320 | 9.6E-87 |
| 12 | g2663.t1 | Gene3D | G3DSA:3.40.50.10490 | - | 321 | 539 | 7.8E-114 |
| 15 | g2663.t1 | Gene3D | G3DSA:1.10.1390.10 | - | 540 | 580 | 2.9E-19 |
| 4 | g2663.t1 | Hamap | MF_00473 | Glucose-6-phosphate isomerase [pgi]. | 77 | 557 | 41.162239 |
| 2 | g2663.t1 | PANTHER | PTHR11469:SF3 | GLUCOSE-6-PHOSPHATE ISOMERASE | 32 | 579 | 8.4E-281 |
| 3 | g2663.t1 | PANTHER | PTHR11469 | GLUCOSE-6-PHOSPHATE ISOMERASE | 32 | 579 | 8.4E-281 |
| 10 | g2663.t1 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 181 | 200 | 2.2E-57 |
| 5 | g2663.t1 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 292 | 310 | 2.2E-57 |
| 7 | g2663.t1 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 369 | 390 | 2.2E-57 |
| 6 | g2663.t1 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 498 | 516 | 2.2E-57 |
| 8 | g2663.t1 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 516 | 530 | 2.2E-57 |
| 9 | g2663.t1 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 530 | 543 | 2.2E-57 |
| 1 | g2663.t1 | Pfam | PF00342 | Phosphoglucose isomerase | 83 | 574 | 3.5E-252 |
| 19 | g2663.t1 | ProSitePatterns | PS00765 | Phosphoglucose isomerase signature 1. | 296 | 309 | - |
| 18 | g2663.t1 | ProSitePatterns | PS00174 | Phosphoglucose isomerase signature 2. | 530 | 547 | - |
| 20 | g2663.t1 | ProSiteProfiles | PS51463 | Glucose-6-phosphate isomerase family profile. | 35 | 581 | 146.635 |
| 11 | g2663.t1 | SUPERFAMILY | SSF53697 | SIS domain | 33 | 579 | 3.06E-223 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004347 | glucose-6-phosphate isomerase activity | MF |
| GO:0006094 | gluconeogenesis | BP |
| GO:0006096 | glycolytic process | BP |
KEGG
Orthology
- This transcript has been annotated with K01810 (glucose-6-phosphate isomerase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
