General information for g2663.t21
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose-6-phosphate isomerase.
Parent gene
- The parent gene g2663 is located on chr_3: 19453861..19455290 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2663 | g2663.t21 | TTS | g2663.t21 | 19450762 | 19450762 |
| chr_3 | g2663 | g2663.t21 | isoform | g2663.t21 | 19450968 | 19452763 |
| chr_3 | g2663 | g2663.t21 | exon | g2663.t21.exon1 | 19450968 | 19451438 |
| chr_3 | g2663 | g2663.t21 | exon | g2663.t21.exon2 | 19451516 | 19451573 |
| chr_3 | g2663 | g2663.t21 | cds | g2663.t21.CDS1 | 19451567 | 19451573 |
| chr_3 | g2663 | g2663.t21 | exon | g2663.t21.exon3 | 19451785 | 19451966 |
| chr_3 | g2663 | g2663.t21 | cds | g2663.t21.CDS2 | 19451785 | 19451966 |
| chr_3 | g2663 | g2663.t21 | exon | g2663.t21.exon4 | 19452025 | 19452185 |
| chr_3 | g2663 | g2663.t21 | cds | g2663.t21.CDS3 | 19452025 | 19452185 |
| chr_3 | g2663 | g2663.t21 | exon | g2663.t21.exon5 | 19452244 | 19452763 |
| chr_3 | g2663 | g2663.t21 | cds | g2663.t21.CDS4 | 19452244 | 19452670 |
| chr_3 | g2663 | g2663.t21 | TSS | g2663.t21 | 19453774 | 19453774 |
Sequences
>g2663.t21 Gene=g2663 Length=1392
GAACACATCAATATAACTGAAGACCGTGCTGTTTTGCATACGGCATTGCGTAATAAATCT
GGCAAACCGGTTCTTGTTGATGGCAAGGATGTTATGCCAGAAATTAATGCTGTGTTAGAG
CACATGAAGGAATTTACAAACCAAGTTGTTAGTGGTGAATGGAAAGGCTATACTGGAAAG
AAAATTACTGACGTGGTTAATATCGGTATTGGCGGAAGCGATCTCGGTCCTTTGATGGTC
ACTGAAGCTCTCAAACCTTATTCAACTGGTTTGAAAATGCATTTTGTATCAAATATTGAT
GGTACACATTTAGCTGAAACACTTAAAAAGATTTCTGCCGAGACAACACTTTTTATTATT
GCGTCAAAAACGTTCACTACACAGGAAACAATTACTAACGCTACATCAGCAAAAACATGG
TTCTTGGATGTTGCTAAAGATCCAAGTGCAGTAGCCAAGCATTTCGTTGCATTATCAACA
AATGAAGAAAAAGCAACAGCATTTGGAATTGACGCAAAAAATATGTTTGCATTCTGGGAC
TTTGTTGGTGGTCGTTATAGCTTGTGGTCTGCTATTGGCTTATCAATTTCGCTCTCTATT
GGCTTTGAAAATTTTGTTAAACTTCAAGAAGGAGCATTCTTTATTGATCAACACTTTCAA
ACAGCTCCATTAGAACAAAATGCACCAGTCATTCTTGCATTATTGGGTATTTGGTATTCT
AACTTTTATGGCGCAGAGACAACAGCTCTTTTACCATATGATCAATATTTGCATCGTTTT
GCTGCCTACTTCCAGCAAGGTGATATGGAAAGTAATGGTAAAGGTGTTACAAAGAGCGGC
AAGCATGTTGATTACAACACTGGACTTTAGGGCGAGCCAGGAACAAATGGACAACATGCA
TTCTATCAATTGATCCATCAGGGAACTCGTTTGATTCCATGTGACTTTATTGCTCCTGCT
CAAACTCAAAATCCTATTGCTGGAGGTATTCATCATAAATTGATTCTTGCCAACTTTTTG
GCACAAACTGAGGCTCTCATGTGCGGTAAGACCGAACAACAAGTCAGAGCTGAATTGGAA
AAAGCTGGTATGAAAGGAGAAAAATTAGAGAATCTTGTTCCACATAAAATCTTTACTGGA
AATCGCCCAACTAACTCAATTGTTGTGAAGAAAGTTACACCATTCACTCTTGGTGCTCTC
ATTGCAATGTATGAGCACAAAATCTTCACACAAGGCATCATTTGGGACGTTAATTCATTT
GATCAATGGGGTGTTGAACTTGGAAAAGCATTGGCAAAGGCAATTGAAGGTGATTTGGCA
AACAATGACAAAGTTTCAAGTCATGATGCATCAACAAACGGCTTGATTAATTTTATCAAA
TCTAGCTGGTAA
>g2663.t21 Gene=g2663 Length=258
MPEINAVLEHMKEFTNQVVSGEWKGYTGKKITDVVNIGIGGSDLGPLMVTEALKPYSTGL
KMHFVSNIDGTHLAETLKKISAETTLFIIASKTFTTQETITNATSAKTWFLDVAKDPSAV
AKHFVALSTNEEKATAFGIDAKNMFAFWDFVGGRYSLWSAIGLSISLSIGFENFVKLQEG
AFFIDQHFQTAPLEQNAPVILALLGIWYSNFYGAETTALLPYDQYLHRFAAYFQQGDMES
NGKGVTKSGKHVDYNTGL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g2663.t21 | CDD | cd05015 | SIS_PGI_1 | 5 | 167 | 7.44186E-77 |
| 8 | g2663.t21 | Gene3D | G3DSA:3.40.50.10490 | - | 1 | 173 | 2.3E-79 |
| 9 | g2663.t21 | Gene3D | G3DSA:3.40.50.10490 | - | 174 | 258 | 4.4E-36 |
| 2 | g2663.t21 | PANTHER | PTHR11469:SF3 | GLUCOSE-6-PHOSPHATE ISOMERASE | 1 | 257 | 1.2E-132 |
| 3 | g2663.t21 | PANTHER | PTHR11469 | GLUCOSE-6-PHOSPHATE ISOMERASE | 1 | 257 | 1.2E-132 |
| 5 | g2663.t21 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 34 | 53 | 3.3E-32 |
| 6 | g2663.t21 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 145 | 163 | 3.3E-32 |
| 4 | g2663.t21 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 222 | 243 | 3.3E-32 |
| 1 | g2663.t21 | Pfam | PF00342 | Phosphoglucose isomerase | 1 | 257 | 1.0E-132 |
| 11 | g2663.t21 | ProSitePatterns | PS00765 | Phosphoglucose isomerase signature 1. | 149 | 162 | - |
| 12 | g2663.t21 | ProSiteProfiles | PS51463 | Glucose-6-phosphate isomerase family profile. | 1 | 258 | 77.106 |
| 7 | g2663.t21 | SUPERFAMILY | SSF53697 | SIS domain | 1 | 257 | 3.89E-109 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004347 | glucose-6-phosphate isomerase activity | MF |
| GO:0006094 | gluconeogenesis | BP |
| GO:0006096 | glycolytic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed