General information for g2663.t47
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose-6-phosphate isomerase.
Parent gene
- The parent gene g2663 is located on chr_3: 19453861..19455290 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2663 | g2663.t47 | isoform | g2663.t47 | 19451837 | 19453861 |
| chr_3 | g2663 | g2663.t47 | exon | g2663.t47.exon1 | 19451837 | 19451959 |
| chr_3 | g2663 | g2663.t47 | cds | g2663.t47.CDS1 | 19451837 | 19451959 |
| chr_3 | g2663 | g2663.t47 | exon | g2663.t47.exon2 | 19452025 | 19452185 |
| chr_3 | g2663 | g2663.t47 | cds | g2663.t47.CDS2 | 19452025 | 19452185 |
| chr_3 | g2663 | g2663.t47 | exon | g2663.t47.exon3 | 19452244 | 19452865 |
| chr_3 | g2663 | g2663.t47 | cds | g2663.t47.CDS3 | 19452244 | 19452865 |
| chr_3 | g2663 | g2663.t47 | exon | g2663.t47.exon4 | 19452950 | 19453133 |
| chr_3 | g2663 | g2663.t47 | cds | g2663.t47.CDS4 | 19452950 | 19453117 |
| chr_3 | g2663 | g2663.t47 | exon | g2663.t47.exon5 | 19453705 | 19453861 |
| chr_3 | g2663 | g2663.t47 | TSS | g2663.t47 | NA | NA |
| chr_3 | g2663 | g2663.t47 | TTS | g2663.t47 | NA | NA |
Sequences
>g2663.t47 Gene=g2663 Length=1247
ATGTCTTATAATGTCGGTATAGAAGAGACTCTACTGACAGCAATGCTGTGGGCTTCTACA
CTATTGACTCCTTCATCTGTTGTACTCATTCGATAGCCGTTTTTTGAGCAAGGTAGTCGG
AGTAATTTTCTTGTATTTGCAGTGATAAATTTTTAAAGTCTATTAAACCGAAAATGTCGA
AGCCTCTTCTTACAACCGATCCTGTTTATCAAAAACTTCAACAATATTACAATGAAAACG
GGGCAAAAATAAACATCAAACAATTATTTGATAGTGATCCAAAACGTTTCGATAAGTTTA
GCTTGACTTTAAAAACACCAAATGACGGTGATATTTTGCTGGATTACTCGAAAAATCGTA
TTACTGATGACGTGTGGAAGCTGTTGTTGCAACTTGCTGAGTCTCGTGGCTTGCAACAAG
CTCGCACTCAAATGTTCAGTGGAGAACACATCAATATAACTGAAGACCGTGCTGTTTTGC
ATACGGCATTGCGTAATAAATCTGGCAAACCGGTTCTTGTTGATGGCAAGGATGTTATGC
CAGAAATTAATGCTGTGTTAGAGCACATGAAGGAATTTACAAACCAAGTTGTTAGTGGTG
AATGGAAAGGCTATACTGGAAAGAAAATTACTGACGTGGTTAATATCGGTATTGGCGGAA
GCGATCTCGGTCCTTTGATGGTCACTGAAGCTCTCAAACCTTATTCAACTGGTTTGAAAA
TGCATTTTGTATCAAATATTGATGGTACACATTTAGCTGAAACACTTAAAAAGATTTCTG
CCGAGACAACACTTTTTATTATTGCGTCAAAAACGTTCACTACACAGGAAACAATTACTA
ACGCTACATCAGCAAAAACATGGTTCTTGGATGTTGCTAAAGATCCAAGTGCAGTAGCCA
AGCATTTCGTTGCATTATCAACAAATGAAGAAAAAGCAACAGCATTTGGAATTGACGCAA
AAAATATGTTTGCATTCTGGGACTTTGTTGGTGGTCGTTATAGCTTGTGGTCTGCTATTG
GCTTATCAATTTCGCTCTCTATTGGCTTTGAAAATTTTGTTAAACTTCAAGAAGGAGCAT
TCTTTATTGATCAACACTTTCAAACAGCTCCATTAGAACAAAATTCATTCTTGCATTATT
GGGTATTTGGTATTCTAACTTTTATGGCGCAGAGACAACAGCTCTTTTACCATATGATCA
ATATTTGCATCGTTTTGCTGCCTACTTCCAGCAAGGTGATATGGAAA
>g2663.t47 Gene=g2663 Length=358
MSKPLLTTDPVYQKLQQYYNENGAKINIKQLFDSDPKRFDKFSLTLKTPNDGDILLDYSK
NRITDDVWKLLLQLAESRGLQQARTQMFSGEHINITEDRAVLHTALRNKSGKPVLVDGKD
VMPEINAVLEHMKEFTNQVVSGEWKGYTGKKITDVVNIGIGGSDLGPLMVTEALKPYSTG
LKMHFVSNIDGTHLAETLKKISAETTLFIIASKTFTTQETITNATSAKTWFLDVAKDPSA
VAKHFVALSTNEEKATAFGIDAKNMFAFWDFVGGRYSLWSAIGLSISLSIGFENFVKLQE
GAFFIDQHFQTAPLEQNSFLHYWVFGILTFMAQRQQLFYHMINICIVLLPTSSKVIWK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g2663.t47 | CDD | cd05015 | SIS_PGI_1 | 126 | 288 | 1.30454E-76 |
| 7 | g2663.t47 | Gene3D | G3DSA:3.40.50.10490 | - | 5 | 106 | 2.9E-33 |
| 8 | g2663.t47 | Gene3D | G3DSA:3.40.50.10490 | - | 107 | 296 | 3.1E-87 |
| 2 | g2663.t47 | PANTHER | PTHR11469:SF3 | GLUCOSE-6-PHOSPHATE ISOMERASE | 6 | 328 | 5.3E-150 |
| 3 | g2663.t47 | PANTHER | PTHR11469 | GLUCOSE-6-PHOSPHATE ISOMERASE | 6 | 328 | 5.3E-150 |
| 5 | g2663.t47 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 155 | 174 | 9.9E-20 |
| 4 | g2663.t47 | PRINTS | PR00662 | Glucose-6-phosphate isomerase signature | 266 | 284 | 9.9E-20 |
| 1 | g2663.t47 | Pfam | PF00342 | Phosphoglucose isomerase | 57 | 318 | 5.7E-130 |
| 10 | g2663.t47 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 336 | - |
| 11 | g2663.t47 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 337 | 357 | - |
| 9 | g2663.t47 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 358 | 358 | - |
| 13 | g2663.t47 | ProSitePatterns | PS00765 | Phosphoglucose isomerase signature 1. | 270 | 283 | - |
| 14 | g2663.t47 | ProSiteProfiles | PS51463 | Glucose-6-phosphate isomerase family profile. | 9 | 328 | 75.909 |
| 6 | g2663.t47 | SUPERFAMILY | SSF53697 | SIS domain | 7 | 328 | 8.06E-117 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004347 | glucose-6-phosphate isomerase activity | MF |
| GO:0006094 | gluconeogenesis | BP |
| GO:0006096 | glycolytic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
