General information for g2663.t53
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose-6-phosphate isomerase.
Parent gene
- The parent gene g2663 is located on chr_3: 19453861..19455290 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2663 | g2663.t53 | isoform | g2663.t53 | 19452370 | 19452842 |
| chr_3 | g2663 | g2663.t53 | exon | g2663.t53.exon1 | 19452370 | 19452842 |
| chr_3 | g2663 | g2663.t53 | cds | g2663.t53.CDS1 | 19452371 | 19452775 |
| chr_3 | g2663 | g2663.t53 | TSS | g2663.t53 | 19453774 | 19453774 |
| chr_3 | g2663 | g2663.t53 | TTS | g2663.t53 | NA | NA |
Sequences
>g2663.t53 Gene=g2663 Length=473
TGATGACGTGTGGAAGCTGTTGTTGCAACTTGCTGAGTCTCGTGGCTTGCAACAAGCTCG
CACTCAAATGTTCAGTGGAGAACACATCAATATAACTGAAGACCGTGCTGTTTTGCATAC
GGCATTGCGTAATAAATCTGGCAAACCGGTTCTTGTTGATGGCAAGGATGTTATGCCAGA
AATTAATGCTGTGTTAGAGCACATGAAGGAATTTACAAACCAAGTTGTTAGTGGTGAATG
GAAAGGCTATACTGGAAAGAAAATTACTGACGTGGTTAATATCGGTATTGGCGGAAGCGA
TCTCGGTCCTTTGATGGTCACTGAAGCTCTCAAACCTTATTCAACTGGTTTGAAAATGCA
TTTTGTATCAAATATTGATGGTACACATTTAGCTGAAACACTTAAAAAGATTTCTGCCGA
GACAACACTTTTTATTATTGCGTCAAAAACGTTCACTACACAGGAAACAATTA
>g2663.t53 Gene=g2663 Length=135
MFSGEHINITEDRAVLHTALRNKSGKPVLVDGKDVMPEINAVLEHMKEFTNQVVSGEWKG
YTGKKITDVVNIGIGGSDLGPLMVTEALKPYSTGLKMHFVSNIDGTHLAETLKKISAETT
LFIIASKTFTTQETI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2663.t53 | CDD | cd05015 | SIS_PGI_1 | 40 | 135 | 0.000 |
| 5 | g2663.t53 | Gene3D | G3DSA:3.40.50.10490 | - | 1 | 16 | 0.000 |
| 6 | g2663.t53 | Gene3D | G3DSA:3.40.50.10490 | - | 17 | 135 | 0.000 |
| 2 | g2663.t53 | PANTHER | PTHR11469:SF5 | GLUCOSE-6-PHOSPHATE ISOMERASE | 1 | 135 | 0.000 |
| 3 | g2663.t53 | PANTHER | PTHR11469 | GLUCOSE-6-PHOSPHATE ISOMERASE | 1 | 135 | 0.000 |
| 1 | g2663.t53 | Pfam | PF00342 | Phosphoglucose isomerase | 1 | 135 | 0.000 |
| 7 | g2663.t53 | ProSiteProfiles | PS51463 | Glucose-6-phosphate isomerase family profile. | 1 | 135 | 41.328 |
| 4 | g2663.t53 | SUPERFAMILY | SSF53697 | SIS domain | 1 | 135 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004347 | glucose-6-phosphate isomerase activity | MF |
| GO:0006094 | gluconeogenesis | BP |
| GO:0006096 | glycolytic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
