General information for g2664.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2.
Parent gene
- The parent gene g2664 is located on chr_3: 19457411..19458832 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2664 | g2664.t3 | isoform | g2664.t3 | 19457411 | 19458832 |
| chr_3 | g2664 | g2664.t3 | exon | g2664.t3.exon1 | 19457411 | 19457412 |
| chr_3 | g2664 | g2664.t3 | exon | g2664.t3.exon2 | 19457578 | 19457824 |
| chr_3 | g2664 | g2664.t3 | cds | g2664.t3.CDS1 | 19457611 | 19457824 |
| chr_3 | g2664 | g2664.t3 | exon | g2664.t3.exon3 | 19457885 | 19458185 |
| chr_3 | g2664 | g2664.t3 | cds | g2664.t3.CDS2 | 19457885 | 19458171 |
| chr_3 | g2664 | g2664.t3 | exon | g2664.t3.exon4 | 19458248 | 19458832 |
| chr_3 | g2664 | g2664.t3 | TSS | g2664.t3 | NA | NA |
| chr_3 | g2664 | g2664.t3 | TTS | g2664.t3 | NA | NA |
Sequences
>g2664.t3 Gene=g2664 Length=1135
TGGAATGTGCATCTCATCATCTTGTGGTAAAATTAATGAATGATGCAGCCCTTCTTGGAC
AAGTAACAATGCTACTAAGAAAAAGAAAACCACAGAATCTCAACAATTTTTATCGACCAC
CGCAAAGTTCTTATGTGAACCAACCAGTTATTCCAAATACTTATGATGTGATTATTAATC
GACAAGAACATGAAGGTTTTGGTTTTGTAATAATCTCATCTTCTAATCAGTCATCCGGCT
CAACAATTGGTAAAATTATACCAAATAGTCCAGCTGATAATGGTCAGCTCAAGATTGGTG
ATCGAATCATTAGAGTTAATGATAATGACATCACAAATATGTCACATGGCGATGTCGTTA
AGATAATCAAGGATTCAGGACTAACAGTTGTGCTCACTGTTAGCAATTCAACAATCGCAC
GTTCTAGTGATTTCATCATAAATGAAGGCAATCATTCACCATACAATTCAAATATTAATA
CTAACAGTAGCAATAGTAACCCATTGAATATGAACTCATTTCCCATGATAACCTGATTGA
TGCGAGGCAAATGATCGGTATCTAGGATGTTATATGGCATGCTTTAATTGTTTACTAACT
CGAGATTCCATCATATTAAAATAAGAGATCAATTAGTTTCAAAATTATTTACCAAAGTAC
TTATAGAGCCTTATGCCTTGAAATAAAAATCTCAATGAAATTTTTGGAGAAGAATTTTTT
TGCCAATAAGTAAGTAAGAATAAATCATACTTAAAAATCTCATAAAAGAATTTGCACACT
CTTTTGGTGTTTAAACAAATAGTGCAAAACTAGAACTGTAGAGAAGCCTTAATAGAAAAA
AAAACTTAAAATCTACGTTAAGACTGAAGATAGTTATCAATTTATTCATATCGAAAATAG
TTTTAACATTATTGCAAAATATAAAAAACCTTTAAAAAAAGTTTTGTAATAATCAAAAAA
AAAGAAGAAATAATCCATGTACCTATTTTCACACATAATCGTTATGCCTACACAATCATG
TATTGTATTGTCAACTCTCTATGTACTTAGATAGTTTAGAAAATTGTTTTATACAGTAAG
AAAAGAAGGTAAATTCTTGTGTAAACAATTTAATTGTAATAAAGTTGCAATAAAA
>g2664.t3 Gene=g2664 Length=166
MNDAALLGQVTMLLRKRKPQNLNNFYRPPQSSYVNQPVIPNTYDVIINRQEHEGFGFVII
SSSNQSSGSTIGKIIPNSPADNGQLKIGDRIIRVNDNDITNMSHGDVVKIIKDSGLTVVL
TVSNSTIARSSDFIINEGNHSPYNSNINTNSSNSNPLNMNSFPMIT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2664.t3 | CDD | cd00992 | PDZ_signaling | 42 | 122 | 0.000 |
| 6 | g2664.t3 | Gene3D | G3DSA:2.30.42.10 | - | 35 | 133 | 0.000 |
| 2 | g2664.t3 | PANTHER | PTHR10316:SF40 | LD27118P-RELATED | 1 | 125 | 0.000 |
| 3 | g2664.t3 | PANTHER | PTHR10316 | MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED | 1 | 125 | 0.000 |
| 1 | g2664.t3 | Pfam | PF00595 | PDZ domain | 45 | 122 | 0.000 |
| 7 | g2664.t3 | ProSiteProfiles | PS50106 | PDZ domain profile. | 44 | 126 | 18.295 |
| 5 | g2664.t3 | SMART | SM00228 | pdz_new | 53 | 126 | 0.000 |
| 4 | g2664.t3 | SUPERFAMILY | SSF50156 | PDZ domain-like | 23 | 125 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
