General information for g2666.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Endophilin-A.
Parent gene
- The parent gene g2666 is located on chr_3: 19469451..19470550 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2666 | g2666.t4 | TTS | g2666.t4 | 19467478 | 19467478 |
| chr_3 | g2666 | g2666.t4 | isoform | g2666.t4 | 19468338 | 19470550 |
| chr_3 | g2666 | g2666.t4 | exon | g2666.t4.exon1 | 19468338 | 19468928 |
| chr_3 | g2666 | g2666.t4 | cds | g2666.t4.CDS1 | 19468340 | 19468928 |
| chr_3 | g2666 | g2666.t4 | exon | g2666.t4.exon2 | 19469065 | 19469333 |
| chr_3 | g2666 | g2666.t4 | cds | g2666.t4.CDS2 | 19469065 | 19469333 |
| chr_3 | g2666 | g2666.t4 | exon | g2666.t4.exon3 | 19469388 | 19469584 |
| chr_3 | g2666 | g2666.t4 | cds | g2666.t4.CDS3 | 19469388 | 19469584 |
| chr_3 | g2666 | g2666.t4 | exon | g2666.t4.exon4 | 19469655 | 19469865 |
| chr_3 | g2666 | g2666.t4 | cds | g2666.t4.CDS4 | 19469655 | 19469865 |
| chr_3 | g2666 | g2666.t4 | exon | g2666.t4.exon5 | 19470231 | 19470550 |
| chr_3 | g2666 | g2666.t4 | cds | g2666.t4.CDS5 | 19470231 | 19470275 |
| chr_3 | g2666 | g2666.t4 | TSS | g2666.t4 | 19470549 | 19470549 |
Sequences
>g2666.t4 Gene=g2666 Length=1588
GCATTTTCTCCATAAAATTTTCTGTGTATGTCAATAACTTTTCAAAAATTATTTTTAAAG
CATAGTAAAACCAACATAATTTAAATATTTTTAGTGTCATTCTATTGTTTGTATACACCG
TCAATTGAAACACATGATTGTATAGTCAAAGAATACAGAAATAGTGTAAAAATTACAAAA
TATATTTTTATGTAAAAAAATTTCGCTCTATAATTAATTCAGTTTCGTTCATCACTCTGA
AGTGGTTTATATAGTCAAGTGGAAACAAAATCATAATGGCTTTTGCAAAGATACAGAAAC
AGTTCAATATTGCGAATCAACTTATCACAGAAAAAGTTTTTAATGGAGAAAAATCAAAAT
TCAATGATGATTTTACTGAAATGGAGAAAAAGACAGATGCAACTGTCGATATGGTTGAAG
ATTTGCAACAAAAAACTAAAGAATTTCTTCAACCTAATCCAGCTGCTCGTGCAAAAATGG
CAGCAATGAAATTGTCTTCAGGTCAAGCAAAAACTCAATATCCTCAAACAGAGGGAATAC
TAGGAAATGCTTGTATGGCCCATGGAAAAAAATTAGGCGAGGATGATATTCTTGGTCAAT
CGTTGATTGAAATTGGAGAATCGCTAAAACAAGTTGCTGATGTCAAATATTCACTCGATA
ATAATGTAAAGCAAAATTTTCTCGAACCACTTCAACATTTACAAAATAATGATATTAAAG
AAGTTTTGCATCATAGAAAAAAGCTGTCAAATCGTCGATTAGATTATGATGCTAAGAGAA
GAAAGCAAAATAAAGGAGGCGTTACAGAAGATGAGATTCGAATTGCACAAGAAAAATTTA
GTGAATCTCTAAGTAATGCATCAACAAGCATGCATCATCTTTTAGAGAATGACGTTGAGC
TTATATCACAATTGGCCGTATTTTCTGAAAGTCTTATGACATATTATCAACAATGTGCTG
AAATTATGCAGGAACTTACAAACAAATTATATGAAAAAAAATCGGAAGCGATGAACAGAC
CGAAGAAAAGTTTCATACCGACCACTCTATCCGACTTAAATATTGATTCACTCTCAATTG
GAAGCGGCAGTAATGATCGACAAAACAACAACTTTAATTCAAATGGTGCGCGTCTTAATA
ATTTTGATAGATTTAAAGCAACTTCATCCTCAAATATTTCCTTTAAACATTCCAATAATA
ATAATATTAATGGTAACAGTAATAGTAATTTTGGCCGTACAAGTAAGTTGTATGGTTCTC
AGTCAAATCTATCTACAGCATCCTCTACAGGTTCACGTTATCAAACTGTACATAATAATA
GCAAAAGCAATTATAATATCAATTCACCTAAATCATCAGCATCGGGTGATATTGATAAAT
GGATGCAAGCGTGGGATGATAATGCAAACAATTATCGCGCACCATCATATCATTCAAATA
AACAAACACATTCCTTTCACAAATTTAATAATAATAATTTCAAAAGTTTTAATTCTAATC
AAACTGCAAATGTGCGAAACTCTTCTTTCAATTCTGTTGATCCATTTGATCCTTTTGATG
ACGATGCTCCATTTTCCGATCCATGGTC
>g2666.t4 Gene=g2666 Length=437
MAFAKIQKQFNIANQLITEKVFNGEKSKFNDDFTEMEKKTDATVDMVEDLQQKTKEFLQP
NPAARAKMAAMKLSSGQAKTQYPQTEGILGNACMAHGKKLGEDDILGQSLIEIGESLKQV
ADVKYSLDNNVKQNFLEPLQHLQNNDIKEVLHHRKKLSNRRLDYDAKRRKQNKGGVTEDE
IRIAQEKFSESLSNASTSMHHLLENDVELISQLAVFSESLMTYYQQCAEIMQELTNKLYE
KKSEAMNRPKKSFIPTTLSDLNIDSLSIGSGSNDRQNNNFNSNGARLNNFDRFKATSSSN
ISFKHSNNNNINGNSNSNFGRTSKLYGSQSNLSTASSTGSRYQTVHNNSKSNYNINSPKS
SASGDIDKWMQAWDDNANNYRAPSYHSNKQTHSFHKFNNNNFKSFNSNQTANVRNSSFNS
VDPFDPFDDDAPFSDPW
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2666.t4 | Gene3D | G3DSA:1.20.1270.60 | Arfaptin | 1 | 244 | 3.3E-68 |
| 7 | g2666.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 330 | 361 | - |
| 6 | g2666.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 416 | 437 | - |
| 2 | g2666.t4 | PANTHER | PTHR14167:SF45 | ENDOPHILIN-A3 | 1 | 262 | 1.0E-76 |
| 3 | g2666.t4 | PANTHER | PTHR14167 | SH3 DOMAIN-CONTAINING | 1 | 262 | 1.0E-76 |
| 1 | g2666.t4 | Pfam | PF03114 | BAR domain | 6 | 238 | 9.4E-59 |
| 9 | g2666.t4 | ProSiteProfiles | PS51021 | BAR domain profile. | 18 | 247 | 26.119 |
| 5 | g2666.t4 | SMART | SM00721 | 5bar | 5 | 240 | 1.1E-60 |
| 4 | g2666.t4 | SUPERFAMILY | SSF103657 | BAR/IMD domain-like | 13 | 238 | 9.59E-60 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
