General information for g2672.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phospholipase B1, membrane-associated.
Parent gene
- The parent gene g2672 is located on chr_3: 19595258..19599329 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2672 | g2672.t1 | isoform | g2672.t1 | 19595258 | 19599329 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon1 | 19595258 | 19595467 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS1 | 19595258 | 19595467 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon2 | 19595534 | 19595651 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS2 | 19595534 | 19595651 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon3 | 19595720 | 19595777 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS3 | 19595720 | 19595777 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon4 | 19595828 | 19596113 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS4 | 19595828 | 19596113 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon5 | 19596186 | 19596284 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS5 | 19596186 | 19596284 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon6 | 19596378 | 19596439 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS6 | 19596378 | 19596439 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon7 | 19596532 | 19596645 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS7 | 19596532 | 19596645 |
| chr_3 | g2672 | g2672.t1 | exon | g2672.t1.exon8 | 19599050 | 19599329 |
| chr_3 | g2672 | g2672.t1 | cds | g2672.t1.CDS8 | 19599050 | 19599329 |
| chr_3 | g2672 | g2672.t1 | TSS | g2672.t1 | NA | NA |
| chr_3 | g2672 | g2672.t1 | TTS | g2672.t1 | NA | NA |
Sequences
>g2672.t1 Gene=g2672 Length=1227
ATGAAACTACTGCAGATTTTTCTAACTGCAATCACAATCATACATTTCACGTATTCGCAA
GAACTTTTTGAGCTTACGACACGTCTGGATGATCCGCGACTCCGATTTCTCTTTCATCGA
TTTCGAAACTTTGTGTTCAATTCAATTGGAAAGACAAGCTATAAAACAAAGGGAGTTTTC
TTACAAGATAAATTTCCCGATAATATGCCATTCCCTTGCGACATAAGAATTGGAAAAAGT
CGCGAGCAACCAAAAAGTATTCATAAATTGAGACCTGGTGATATTTCAGTAGTCGGCGCA
TTGGGTGATAGTTTAACATGTTCAACCGGTGCTATGGCTGAAAGAATGATGGAGTTGTCG
ATGGAAAATCGCGGACTCGCATGGAGTATTGGAGGTCAATGGAATTGGAGAAATGCAACA
ACTTTACCGAATATATTGAAAGAGTTCAATCCATCGCTCATTGGTTACTCATTCGACGAT
TCATTTCCTTTCCATAAGGCATCGCAATTTAATCTTGCTGAAATTGGTGCTGTTTCAAAC
GATATGCCCTTTATGGCACGTGCTCTTGTGAAGCGTATCAAAAGTGATAGACGAGTAAAT
TTCAAATATGACTGGAAAGTTGTTACCATCTCTATAGGTGGCAACGACTTCTGTAGTTTC
ATTTGTCTTATGGATAAACCTGAGCGACTTCCTGATATGCATCGCATTTCGTTGATGAAA
ACTTTGCGGTATTTGAAGAACAATTTGCCTCGGGCCTTTGTCAACATTGTGTCAGTGCCA
CACGTAGAGACTGTCATGATTTATCCAGGAAAGCCGAGATCATGCAGTTTTATTCATCGT
GGTGAATGCGCTTGTTGGGTTGGACCATTAGCTAATGTCACTAAGGAATCTCGAGAAAGA
TGGATGAAAATTCAACAACGTTTCATACAGGTTGAAGAAGAGGTCGCAAAATCAGAAGAG
TTTCGAAGACTTGATGAATTTGCAGTTATGTATCAGCCTTGGTCCACCAATGTCTCGCTC
ATCGTCGATGGAAAGCGTGATTTATCGCTTTTGTCATTTGATTGCTTTCATCTTTCACAA
AAAGGTAATGCATGGGGTGGAACAGCACTTTGGAATAACATGATTGAACCGGTTAACAAG
AAGACTATCAACTGGTACAATCCTTTGAAAAAATTCAATTGTCCTACTCGAGAGCATCCA
TATATTTATACTTATGATAATAGTTAA
>g2672.t1 Gene=g2672 Length=408
MKLLQIFLTAITIIHFTYSQELFELTTRLDDPRLRFLFHRFRNFVFNSIGKTSYKTKGVF
LQDKFPDNMPFPCDIRIGKSREQPKSIHKLRPGDISVVGALGDSLTCSTGAMAERMMELS
MENRGLAWSIGGQWNWRNATTLPNILKEFNPSLIGYSFDDSFPFHKASQFNLAEIGAVSN
DMPFMARALVKRIKSDRRVNFKYDWKVVTISIGGNDFCSFICLMDKPERLPDMHRISLMK
TLRYLKNNLPRAFVNIVSVPHVETVMIYPGKPRSCSFIHRGECACWVGPLANVTKESRER
WMKIQQRFIQVEEEVAKSEEFRRLDEFAVMYQPWSTNVSLIVDGKRDLSLLSFDCFHLSQ
KGNAWGGTALWNNMIEPVNKKTINWYNPLKKFNCPTREHPYIYTYDNS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g2672.t1 | CDD | cd01824 | Phospholipase_B_like | 86 | 379 | 3.11846E-123 |
| 6 | g2672.t1 | Gene3D | G3DSA:3.40.50.1110 | - | 78 | 370 | 7.0E-7 |
| 2 | g2672.t1 | PANTHER | PTHR21325 | PHOSPHOLIPASE B, PLB1 | 64 | 408 | 6.5E-109 |
| 3 | g2672.t1 | PANTHER | PTHR21325:SF31 | PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED | 64 | 408 | 6.5E-109 |
| 1 | g2672.t1 | Pfam | PF00657 | GDSL-like Lipase/Acylhydrolase | 99 | 364 | 1.9E-6 |
| 8 | g2672.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 9 | g2672.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 10 | g2672.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 14 | - |
| 11 | g2672.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 19 | - |
| 7 | g2672.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 408 | - |
| 4 | g2672.t1 | SUPERFAMILY | SSF52266 | SGNH hydrolase | 98 | 376 | 2.0E-13 |
| 5 | g2672.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004620 | phospholipase activity | MF |
| GO:0016788 | hydrolase activity, acting on ester bonds | MF |
KEGG
Orthology
- This transcript has been annotated with K14621 (phospholipase B1, membrane-associated)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed