General information for g2793.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome regulatory subunit 6A-A.
Parent gene
- The parent gene g2793 is located on chr_3: 20302504..20303399 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2793 | g2793.t12 | TSS | g2793.t12 | 20301584 | 20301584 |
| chr_3 | g2793 | g2793.t12 | isoform | g2793.t12 | 20301681 | 20303092 |
| chr_3 | g2793 | g2793.t12 | exon | g2793.t12.exon1 | 20301681 | 20302324 |
| chr_3 | g2793 | g2793.t12 | cds | g2793.t12.CDS1 | 20301681 | 20302324 |
| chr_3 | g2793 | g2793.t12 | exon | g2793.t12.exon2 | 20302390 | 20302423 |
| chr_3 | g2793 | g2793.t12 | cds | g2793.t12.CDS2 | 20302390 | 20302423 |
| chr_3 | g2793 | g2793.t12 | exon | g2793.t12.exon3 | 20302487 | 20302958 |
| chr_3 | g2793 | g2793.t12 | cds | g2793.t12.CDS3 | 20302487 | 20302958 |
| chr_3 | g2793 | g2793.t12 | exon | g2793.t12.exon4 | 20303018 | 20303092 |
| chr_3 | g2793 | g2793.t12 | cds | g2793.t12.CDS4 | 20303018 | 20303025 |
| chr_3 | g2793 | g2793.t12 | TTS | g2793.t12 | 20303186 | 20303186 |
Sequences
>g2793.t12 Gene=g2793 Length=1225
ATGGCAGGAACACTTGAAGATAAATCAATTTGGGAAGACGAAGAATTACTTGGTGAAGAA
GTCTTGCGTATGCCAACAGAAGATATTCAAAATCGAACTCGATTGATGGACAATGAAATT
AAAATAATGAAGTCTGAAGTGATGAGAATCAATCATGAGTTACAGGCACAAAATGAGAAA
ATTAAGGACAATACTGAGAAGATTAAAGTGAACAAGACACTTCCCTATTTGGTTTCAAAT
GTTATTGAATTGCTCGATATAGATCCACAAGAAGAAGAAGATGATGGTGCAGTAAATTTG
CTTGATTCACAACGCAAAGGAAAGTGTGCAGTTATCAAGACTTCTACTCGTCAAACCTAT
TTCTTACCAGTTATCGGTTTAGTTGATCCTGAAAAATTAAAACCAGGCGATTTAGTTGGT
GTTAACAAAGATTCGTATTTGATTTTGGAAACACTTCCAGCAGAATATGATGCTCGAGTT
AAAGCTATGGAGGTTGATGAACGCCCGACAGAGCAATATTCGGATATTGGCGGTTTAGAT
AAGCAAATTCAAGAGCTGATCGAGGCAGTAGTTTTGCCAATGACACATAAAGAAAAATTC
AAAAATCTCGGTATTCATCCACCAAAAGGTGTACTTTTATATGGTCCACCAGGTACTGGC
AAAACTTTACTTGCAAGAGCATGTGCAGCTCAAACAAAGTCAACATTTTTAAAGCTTGCT
GGTCCTCAGCTCGTACAGATGTTTATTGGTGATGGTGCAAAATTAGTGCGTGATGCATTT
GCCCTTGCTAAAGAGAAAGCTCCTGCAATCATTTTTATCGATGAATTAGATGCTATAGGA
ACTAAACGTTTTGACTCAGAAAAGGCTGGTGATCGTGAAGTTCAGCGTACTATGTTAGAA
TTATTGAATCAATTGGATGGCTTTAGTTCGCAAGCCGATATCAAAGTTATTGCTGCTACA
AACCGTGTTGATATCTTAGATCCTGCTCTTCTTCGTTCAGGTCGTTTAGATCGTAAAATT
GAATTCCCACATCCTAACGAAGAAGCACGTGCACGTATTATGCAAATTCATTCAAGAAAA
ATGAACGTTAGTCCAGATGTTAATTTTGAAGAATTAGCAAGAACGACAGACGATTTCAAT
GGAGCACAATACACATGAAGACTTTATGGATGCAATTATGGAAGTACAGGCTAAGAAGAA
AGCCAATTTGAATTATTATGCTTAA
>g2793.t12 Gene=g2793 Length=385
MAGTLEDKSIWEDEELLGEEVLRMPTEDIQNRTRLMDNEIKIMKSEVMRINHELQAQNEK
IKDNTEKIKVNKTLPYLVSNVIELLDIDPQEEEDDGAVNLLDSQRKGKCAVIKTSTRQTY
FLPVIGLVDPEKLKPGDLVGVNKDSYLILETLPAEYDARVKAMEVDERPTEQYSDIGGLD
KQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLA
GPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLE
LLNQLDGFSSQADIKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARARIMQIHSRK
MNVSPDVNFEELARTTDDFNGAQYT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g2793.t12 | CDD | cd00009 | AAA | 177 | 343 | 7.45696E-24 |
| 9 | g2793.t12 | Coils | Coil | Coil | 40 | 71 | - |
| 8 | g2793.t12 | Gene3D | G3DSA:2.40.50.140 | - | 38 | 162 | 2.0E-20 |
| 6 | g2793.t12 | Gene3D | G3DSA:3.40.50.300 | - | 163 | 344 | 1.3E-64 |
| 7 | g2793.t12 | Gene3D | G3DSA:1.10.8.60 | - | 345 | 385 | 1.5E-10 |
| 3 | g2793.t12 | PANTHER | PTHR23073 | 26S PROTEASOME REGULATORY SUBUNIT | 13 | 383 | 1.3E-224 |
| 4 | g2793.t12 | PANTHER | PTHR23073:SF90 | 26S PROTEASOME REGULATORY SUBUNIT 6A | 13 | 383 | 1.3E-224 |
| 1 | g2793.t12 | Pfam | PF16450 | Proteasomal ATPase OB C-terminal domain | 79 | 153 | 4.8E-17 |
| 2 | g2793.t12 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | 211 | 343 | 1.6E-41 |
| 11 | g2793.t12 | ProSitePatterns | PS00674 | AAA-protein family signature. | 314 | 332 | - |
| 12 | g2793.t12 | SMART | SM00382 | AAA_5 | 207 | 346 | 8.3E-23 |
| 5 | g2793.t12 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 172 | 383 | 4.95E-60 |
| 13 | g2793.t12 | TIGRFAM | TIGR01242 | 26Sp45: 26S proteasome subunit P45 family | 58 | 383 | 4.5E-115 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0036402 | proteasome-activating activity | MF |
| GO:0030163 | protein catabolic process | BP |
| GO:0005737 | cytoplasm | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed