General information for g2797.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Acetylcholinesterase.
Parent gene
- The parent gene g2797 is located on chr_3: 20317729..20323367 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2797 | g2797.t1 | isoform | g2797.t1 | 20317729 | 20323367 |
| chr_3 | g2797 | g2797.t1 | exon | g2797.t1.exon1 | 20317729 | 20317844 |
| chr_3 | g2797 | g2797.t1 | cds | g2797.t1.CDS1 | 20317729 | 20317844 |
| chr_3 | g2797 | g2797.t1 | exon | g2797.t1.exon2 | 20317966 | 20318135 |
| chr_3 | g2797 | g2797.t1 | cds | g2797.t1.CDS2 | 20317966 | 20318135 |
| chr_3 | g2797 | g2797.t1 | exon | g2797.t1.exon3 | 20318204 | 20319038 |
| chr_3 | g2797 | g2797.t1 | cds | g2797.t1.CDS3 | 20318204 | 20319038 |
| chr_3 | g2797 | g2797.t1 | exon | g2797.t1.exon4 | 20319105 | 20319713 |
| chr_3 | g2797 | g2797.t1 | cds | g2797.t1.CDS4 | 20319105 | 20319713 |
| chr_3 | g2797 | g2797.t1 | exon | g2797.t1.exon5 | 20319873 | 20320061 |
| chr_3 | g2797 | g2797.t1 | cds | g2797.t1.CDS5 | 20319873 | 20320061 |
| chr_3 | g2797 | g2797.t1 | exon | g2797.t1.exon6 | 20322938 | 20323367 |
| chr_3 | g2797 | g2797.t1 | cds | g2797.t1.CDS6 | 20322938 | 20323367 |
| chr_3 | g2797 | g2797.t1 | TSS | g2797.t1 | NA | NA |
| chr_3 | g2797 | g2797.t1 | TTS | g2797.t1 | NA | NA |
Sequences
>g2797.t1 Gene=g2797 Length=2349
ATGGAGATGGTTTTTAAAAAAGGTGTGGTGGAAGCCTTTTTTAAACGTCCAAAAAAGCAC
GGGCATATAGCACTCGCTCTTTATAGCATAGGACTATATACAGTTTTACAATTGCAGCTA
GTCAGTGCGAGGCATCATGATTTAGGGAAATTATTAGCCGTCACCAACAGCAACAATAAT
AATATAAATAATGATAATCTTATAACTAACAACAACAATAACAACAATATTAATTTCAAT
GTTAATGTATTAAGCAGTCTACAACATGCTCAAATAAACCATAGTCACGATAATGAAGAA
TTAAAGCAGCAGCCGCAACAAGAACCTCCATTACTCAGTCAGCAGCAGCCAATATTAGGA
CAAAAAATCACTCAACAAACGCTTGGTGCTGATATTGGCCCGAGCGGTGCTGTTCTATCA
AAGGACGATGACACATTTTTTACATTGGACGTTTATTTAGGTCACGGTGACGCAGTGCGT
GTAGTCGATCCTGAATTAGGGAAATTGGAAAGGGAAAATGTAGGGCATGAATTGCCGCAT
GGAATCAGTTTAAATACACCAATTTTAGGTACAACATCGACATCAACGAGACGTCATACA
CGACGTGAATCGAATCCTGATGTAGAAGAGAACGATCCGCTAATTATTACTACCGACAAA
GGAAAGGTGCGTGGATTAACACTTACATCGCCAACGGGAAGAAAGGTCGATGCTTGGCTC
GGTATTCCGTACGCTCAGCCACCATTGGGTGCACTTCGATTTAGACATCCGCGTCCTGCT
GAGAAATGGCAAGGAATTTTCAATGCTACGAAACCACCAAACTCTTGTGTTCAAATTGTC
GATACCGTTTTTGGAGATTTTCCTGGTGCAACCATGTGGAATCCAAATACTGAGCTCAAC
GAGGATTGTCTATATGTAAATGTTGTAGTGCCGAGTCCGCGTCCAAAAAAGGCAGTTGTT
ATGCTATGGATTTTTGGTGGTGGATTTTATTCTGGTACATCAACACTCGACGTTTATGAT
CATCGAACACTTGCCGCAGAAGAAAATGTCATTATTGTATCAATGCAATATCGTGTTGCT
AGTTTAGGCTTTTTATATCTCGGCACACCCGATGCTCCAGGAAATTCTGGTCTTTTTGAT
CAAAACTTGGCATTGCGATGGGTACGCGATAACATTCATCGATTTGGTGGTGATCCAAAC
AAAATTTGTCTATTTGGAGAAAGTGCTGGTGCGGTTAGTGTATCAATGCATCTGTTATCT
CCACTTTCTCGTGACCTATTTCAACGTGCGATTCTTGAAAGTGGATCACCAACTGCACCA
TGGGCATTAGTAACAAGAGAAGAAGCAACATTGCGAGCATTAAGATTAGCTGAAGCTGTT
GGATGTCCACATGATCGTAAAAAACTAGGAGAAACAGTCGAATGTCTTCGTAACAAGGAT
GCCAAAGAATTAGTTGATAATGAATGGGGTACACTTGGCATTTGTGAATTTCCATTTGTG
CCCGTTGTCGATGGTGCATTCCTGGACGAAACACCAATAAGATCACTAACGAGCGGTCGT
TTCAAGAAGACAGAAATATTGACGGGAAGTAACAGTGAGGAGGGTTATTACTTCATAATT
TATTACCTTACGGAATTACTGCGAAAAGAGGAGGGTATAACGGTTTCGCGTGAAGAATTT
CTACAAGCGGTACGCGAATTAAATCCATATGTTAATGGTGCTGCACGACAGGCAATCATT
TTCGAATATACTGACTGGAATGAACCGGATAATCCGCATAGCAATCGCGATGCTCTCGAT
AAGATGGTTGGAGACTATCATTTCACATGCAATGTCAATGAATTTGCTCAACGTTATGCT
GAAGAGGGTAATAATGTGTACATGTACTTTTATTCACATCGCAGTAAAAGCAATCCTTGG
CCACATTGGACTGGTGTTATGCATGGTGATGAAATTAGCTACGTGTTCGGCGAGCCGTTA
AATCCAAAGCTTGATTTTCTTGAGGAGGAGAAACAATTTAGTCGACGAATCATGCGATAT
TGGGCCAACTTTGCGAGAACTGGCAATCCTAATCCCGGCTTAATCGATGAGTTGCCAGAA
TGGCCTCTTCATACTGCACAAAGCAGACAATATTTAGAATTAAGTATGAATTCATCACAT
ATTGGACGTGGTCCTCGCTTGAGACAATGTGCTTTTTGGAAGAAATATTTGCCTGAATTA
ATAAGACAAACAAATCTTCAAGCAGAATCAACAACACCTGCAGCACCTTGCAAAAATAGT
GCAGTCTTGTTCAAGTCACAAATGTTAGTAATCACAATAATGATGCTATTAACCATCTTC
AAGAATTGA
>g2797.t1 Gene=g2797 Length=782
MEMVFKKGVVEAFFKRPKKHGHIALALYSIGLYTVLQLQLVSARHHDLGKLLAVTNSNNN
NINNDNLITNNNNNNNINFNVNVLSSLQHAQINHSHDNEELKQQPQQEPPLLSQQQPILG
QKITQQTLGADIGPSGAVLSKDDDTFFTLDVYLGHGDAVRVVDPELGKLERENVGHELPH
GISLNTPILGTTSTSTRRHTRRESNPDVEENDPLIITTDKGKVRGLTLTSPTGRKVDAWL
GIPYAQPPLGALRFRHPRPAEKWQGIFNATKPPNSCVQIVDTVFGDFPGATMWNPNTELN
EDCLYVNVVVPSPRPKKAVVMLWIFGGGFYSGTSTLDVYDHRTLAAEENVIIVSMQYRVA
SLGFLYLGTPDAPGNSGLFDQNLALRWVRDNIHRFGGDPNKICLFGESAGAVSVSMHLLS
PLSRDLFQRAILESGSPTAPWALVTREEATLRALRLAEAVGCPHDRKKLGETVECLRNKD
AKELVDNEWGTLGICEFPFVPVVDGAFLDETPIRSLTSGRFKKTEILTGSNSEEGYYFII
YYLTELLRKEEGITVSREEFLQAVRELNPYVNGAARQAIIFEYTDWNEPDNPHSNRDALD
KMVGDYHFTCNVNEFAQRYAEEGNNVYMYFYSHRSKSNPWPHWTGVMHGDEISYVFGEPL
NPKLDFLEEEKQFSRRIMRYWANFARTGNPNPGLIDELPEWPLHTAQSRQYLELSMNSSH
IGRGPRLRQCAFWKKYLPELIRQTNLQAESTTPAAPCKNSAVLFKSQMLVITIMMLLTIF
KN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g2797.t1 | CDD | cd00312 | Esterase_lipase | 215 | 723 | 0.0 |
| 11 | g2797.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 210 | 750 | 3.4E-194 |
| 2 | g2797.t1 | PANTHER | PTHR43918:SF3 | ACETYLCHOLINESTERASE | 205 | 757 | 4.4E-240 |
| 3 | g2797.t1 | PANTHER | PTHR43918 | ACETYLCHOLINESTERASE | 205 | 757 | 4.4E-240 |
| 9 | g2797.t1 | PRINTS | PR00878 | Cholinesterase signature | 281 | 295 | 1.4E-30 |
| 8 | g2797.t1 | PRINTS | PR00878 | Cholinesterase signature | 325 | 354 | 1.4E-30 |
| 7 | g2797.t1 | PRINTS | PR00878 | Cholinesterase signature | 535 | 543 | 1.4E-30 |
| 6 | g2797.t1 | PRINTS | PR00878 | Cholinesterase signature | 602 | 610 | 1.4E-30 |
| 5 | g2797.t1 | PRINTS | PR00878 | Cholinesterase signature | 640 | 647 | 1.4E-30 |
| 4 | g2797.t1 | PRINTS | PR00878 | Cholinesterase signature | 648 | 660 | 1.4E-30 |
| 1 | g2797.t1 | Pfam | PF00135 | Carboxylesterase family | 214 | 733 | 6.4E-167 |
| 12 | g2797.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 20 | - |
| 16 | g2797.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 40 | - |
| 14 | g2797.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 41 | 761 | - |
| 15 | g2797.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 762 | 780 | - |
| 13 | g2797.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 781 | 782 | - |
| 19 | g2797.t1 | ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. | 301 | 311 | - |
| 20 | g2797.t1 | ProSitePatterns | PS00122 | Carboxylesterases type-B serine active site. | 395 | 410 | - |
| 10 | g2797.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 212 | 742 | 9.03E-157 |
| 18 | g2797.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 43 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004104 | cholinesterase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01049 (acetylcholinesterase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed