General information for g2797.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Acetylcholinesterase.
Parent gene
- The parent gene g2797 is located on chr_3: 20317729..20323367 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2797 | g2797.t2 | isoform | g2797.t2 | 20317729 | 20323367 |
| chr_3 | g2797 | g2797.t2 | exon | g2797.t2.exon1 | 20317729 | 20317844 |
| chr_3 | g2797 | g2797.t2 | cds | g2797.t2.CDS1 | 20317729 | 20317844 |
| chr_3 | g2797 | g2797.t2 | exon | g2797.t2.exon2 | 20317966 | 20318135 |
| chr_3 | g2797 | g2797.t2 | cds | g2797.t2.CDS2 | 20317966 | 20318135 |
| chr_3 | g2797 | g2797.t2 | exon | g2797.t2.exon3 | 20318204 | 20319038 |
| chr_3 | g2797 | g2797.t2 | cds | g2797.t2.CDS3 | 20318204 | 20319038 |
| chr_3 | g2797 | g2797.t2 | exon | g2797.t2.exon4 | 20319105 | 20319713 |
| chr_3 | g2797 | g2797.t2 | cds | g2797.t2.CDS4 | 20319105 | 20319713 |
| chr_3 | g2797 | g2797.t2 | exon | g2797.t2.exon5 | 20319873 | 20320031 |
| chr_3 | g2797 | g2797.t2 | cds | g2797.t2.CDS5 | 20319873 | 20320031 |
| chr_3 | g2797 | g2797.t2 | exon | g2797.t2.exon6 | 20322938 | 20323367 |
| chr_3 | g2797 | g2797.t2 | cds | g2797.t2.CDS6 | 20322938 | 20323367 |
| chr_3 | g2797 | g2797.t2 | TSS | g2797.t2 | NA | NA |
| chr_3 | g2797 | g2797.t2 | TTS | g2797.t2 | NA | NA |
Sequences
>g2797.t2 Gene=g2797 Length=2319
ATGGAGATGGTTTTTAAAAAAGGTGTGGTGGAAGCCTTTTTTAAACGTCCAAAAAAGCAC
GGGCATATAGCACTCGCTCTTTATAGCATAGGACTATATACAGTTTTACAATTGCAGCTA
GTCAGTGCGAGGCATCATGATTTAGGGAAATTATTAGCCGTCACCAACAGCAACAATAAT
AATATAAATAATGATAATCTTATAACTAACAACAACAATAACAACAATATTAATTTCAAT
GTTAATGTATTAAGCAGTCTACAACATGCTCAAATAAACCATAGTCACGATAATGAAGAA
TTAAAGCAGCAGCCGCAACAAGAACCTCCATTACTCAGTCAGCAGCAGCCAATATTAGGA
CAAAAAATCACTCAACAAACGCTTGGTGCTGATATTGGCCCGAGCGGTGCTGTTCTATCA
AAGGACGATGGTCACGGTGACGCAGTGCGTGTAGTCGATCCTGAATTAGGGAAATTGGAA
AGGGAAAATGTAGGGCATGAATTGCCGCATGGAATCAGTTTAAATACACCAATTTTAGGT
ACAACATCGACATCAACGAGACGTCATACACGACGTGAATCGAATCCTGATGTAGAAGAG
AACGATCCGCTAATTATTACTACCGACAAAGGAAAGGTGCGTGGATTAACACTTACATCG
CCAACGGGAAGAAAGGTCGATGCTTGGCTCGGTATTCCGTACGCTCAGCCACCATTGGGT
GCACTTCGATTTAGACATCCGCGTCCTGCTGAGAAATGGCAAGGAATTTTCAATGCTACG
AAACCACCAAACTCTTGTGTTCAAATTGTCGATACCGTTTTTGGAGATTTTCCTGGTGCA
ACCATGTGGAATCCAAATACTGAGCTCAACGAGGATTGTCTATATGTAAATGTTGTAGTG
CCGAGTCCGCGTCCAAAAAAGGCAGTTGTTATGCTATGGATTTTTGGTGGTGGATTTTAT
TCTGGTACATCAACACTCGACGTTTATGATCATCGAACACTTGCCGCAGAAGAAAATGTC
ATTATTGTATCAATGCAATATCGTGTTGCTAGTTTAGGCTTTTTATATCTCGGCACACCC
GATGCTCCAGGAAATTCTGGTCTTTTTGATCAAAACTTGGCATTGCGATGGGTACGCGAT
AACATTCATCGATTTGGTGGTGATCCAAACAAAATTTGTCTATTTGGAGAAAGTGCTGGT
GCGGTTAGTGTATCAATGCATCTGTTATCTCCACTTTCTCGTGACCTATTTCAACGTGCG
ATTCTTGAAAGTGGATCACCAACTGCACCATGGGCATTAGTAACAAGAGAAGAAGCAACA
TTGCGAGCATTAAGATTAGCTGAAGCTGTTGGATGTCCACATGATCGTAAAAAACTAGGA
GAAACAGTCGAATGTCTTCGTAACAAGGATGCCAAAGAATTAGTTGATAATGAATGGGGT
ACACTTGGCATTTGTGAATTTCCATTTGTGCCCGTTGTCGATGGTGCATTCCTGGACGAA
ACACCAATAAGATCACTAACGAGCGGTCGTTTCAAGAAGACAGAAATATTGACGGGAAGT
AACAGTGAGGAGGGTTATTACTTCATAATTTATTACCTTACGGAATTACTGCGAAAAGAG
GAGGGTATAACGGTTTCGCGTGAAGAATTTCTACAAGCGGTACGCGAATTAAATCCATAT
GTTAATGGTGCTGCACGACAGGCAATCATTTTCGAATATACTGACTGGAATGAACCGGAT
AATCCGCATAGCAATCGCGATGCTCTCGATAAGATGGTTGGAGACTATCATTTCACATGC
AATGTCAATGAATTTGCTCAACGTTATGCTGAAGAGGGTAATAATGTGTACATGTACTTT
TATTCACATCGCAGTAAAAGCAATCCTTGGCCACATTGGACTGGTGTTATGCATGGTGAT
GAAATTAGCTACGTGTTCGGCGAGCCGTTAAATCCAAAGCTTGATTTTCTTGAGGAGGAG
AAACAATTTAGTCGACGAATCATGCGATATTGGGCCAACTTTGCGAGAACTGGCAATCCT
AATCCCGGCTTAATCGATGAGTTGCCAGAATGGCCTCTTCATACTGCACAAAGCAGACAA
TATTTAGAATTAAGTATGAATTCATCACATATTGGACGTGGTCCTCGCTTGAGACAATGT
GCTTTTTGGAAGAAATATTTGCCTGAATTAATAAGACAAACAAATCTTCAAGCAGAATCA
ACAACACCTGCAGCACCTTGCAAAAATAGTGCAGTCTTGTTCAAGTCACAAATGTTAGTA
ATCACAATAATGATGCTATTAACCATCTTCAAGAATTGA
>g2797.t2 Gene=g2797 Length=772
MEMVFKKGVVEAFFKRPKKHGHIALALYSIGLYTVLQLQLVSARHHDLGKLLAVTNSNNN
NINNDNLITNNNNNNNINFNVNVLSSLQHAQINHSHDNEELKQQPQQEPPLLSQQQPILG
QKITQQTLGADIGPSGAVLSKDDGHGDAVRVVDPELGKLERENVGHELPHGISLNTPILG
TTSTSTRRHTRRESNPDVEENDPLIITTDKGKVRGLTLTSPTGRKVDAWLGIPYAQPPLG
ALRFRHPRPAEKWQGIFNATKPPNSCVQIVDTVFGDFPGATMWNPNTELNEDCLYVNVVV
PSPRPKKAVVMLWIFGGGFYSGTSTLDVYDHRTLAAEENVIIVSMQYRVASLGFLYLGTP
DAPGNSGLFDQNLALRWVRDNIHRFGGDPNKICLFGESAGAVSVSMHLLSPLSRDLFQRA
ILESGSPTAPWALVTREEATLRALRLAEAVGCPHDRKKLGETVECLRNKDAKELVDNEWG
TLGICEFPFVPVVDGAFLDETPIRSLTSGRFKKTEILTGSNSEEGYYFIIYYLTELLRKE
EGITVSREEFLQAVRELNPYVNGAARQAIIFEYTDWNEPDNPHSNRDALDKMVGDYHFTC
NVNEFAQRYAEEGNNVYMYFYSHRSKSNPWPHWTGVMHGDEISYVFGEPLNPKLDFLEEE
KQFSRRIMRYWANFARTGNPNPGLIDELPEWPLHTAQSRQYLELSMNSSHIGRGPRLRQC
AFWKKYLPELIRQTNLQAESTTPAAPCKNSAVLFKSQMLVITIMMLLTIFKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g2797.t2 | CDD | cd00312 | Esterase_lipase | 205 | 713 | 0.0 |
| 11 | g2797.t2 | Gene3D | G3DSA:3.40.50.1820 | - | 200 | 740 | 3.3E-194 |
| 2 | g2797.t2 | PANTHER | PTHR43918:SF3 | ACETYLCHOLINESTERASE | 195 | 747 | 4.1E-240 |
| 3 | g2797.t2 | PANTHER | PTHR43918 | ACETYLCHOLINESTERASE | 195 | 747 | 4.1E-240 |
| 8 | g2797.t2 | PRINTS | PR00878 | Cholinesterase signature | 271 | 285 | 1.3E-30 |
| 6 | g2797.t2 | PRINTS | PR00878 | Cholinesterase signature | 315 | 344 | 1.3E-30 |
| 9 | g2797.t2 | PRINTS | PR00878 | Cholinesterase signature | 525 | 533 | 1.3E-30 |
| 7 | g2797.t2 | PRINTS | PR00878 | Cholinesterase signature | 592 | 600 | 1.3E-30 |
| 5 | g2797.t2 | PRINTS | PR00878 | Cholinesterase signature | 630 | 637 | 1.3E-30 |
| 4 | g2797.t2 | PRINTS | PR00878 | Cholinesterase signature | 638 | 650 | 1.3E-30 |
| 1 | g2797.t2 | Pfam | PF00135 | Carboxylesterase family | 204 | 723 | 6.2E-167 |
| 12 | g2797.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 20 | - |
| 16 | g2797.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 40 | - |
| 14 | g2797.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 41 | 751 | - |
| 15 | g2797.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 752 | 770 | - |
| 13 | g2797.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 771 | 772 | - |
| 19 | g2797.t2 | ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. | 291 | 301 | - |
| 20 | g2797.t2 | ProSitePatterns | PS00122 | Carboxylesterases type-B serine active site. | 385 | 400 | - |
| 10 | g2797.t2 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 202 | 732 | 8.8E-157 |
| 18 | g2797.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 43 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004104 | cholinesterase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01049 (acetylcholinesterase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed