General information for g2857.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Transcriptional activator cubitus interruptus.
Parent gene
- The parent gene g2857 is located on chr_3: 20689763..20712627 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2857 | g2857.t1 | TTS | g2857.t1 | 20689381 | 20689381 |
| chr_3 | g2857 | g2857.t1 | isoform | g2857.t1 | 20689763 | 20712627 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon1 | 20689763 | 20691352 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS1 | 20689763 | 20691352 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon2 | 20691606 | 20692043 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS2 | 20691606 | 20692043 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon3 | 20692120 | 20692284 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS3 | 20692120 | 20692284 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon4 | 20692965 | 20692995 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS4 | 20692965 | 20692995 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon5 | 20693067 | 20693776 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS5 | 20693067 | 20693776 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon6 | 20693851 | 20694365 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS6 | 20693851 | 20694365 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon7 | 20694432 | 20694625 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS7 | 20694432 | 20694625 |
| chr_3 | g2857 | g2857.t1 | exon | g2857.t1.exon8 | 20712314 | 20712627 |
| chr_3 | g2857 | g2857.t1 | cds | g2857.t1.CDS8 | 20712314 | 20712627 |
| chr_3 | g2857 | g2857.t1 | TSS | g2857.t1 | 20713062 | 20713062 |
Sequences
>g2857.t1 Gene=g2857 Length=3957
ATGAAGGGTCCTTTTGGTGAAGTTTATCCTTACCATCATCATTTGCACAATCAAATACTC
AATAGTGCATCGAATGGATTATTTCGCAGTGGTGGTGACATCAATCAATTAGCATCTCAA
CAGCAGGCCAATGCTGCTGCTTCGCACTTTGCCGCATCAGCCGCCAATAACAATTCATTA
CACTTTCCGTCGGCATTCGTTGCTTTTCACAATACACAAATGGCGGCTGCTGCTGCTGCT
GCAGCAAGTGGACAACAACGTTCTACACATGAATCAAACTTCAATCCGGCATCGTCATTT
CACTATCCACATGGACCATTATTTACTGAAGTGCAGTTACTTAATTCATCGTCGAGAAAT
TCACTCGTCCCAGTATTGCCATTATCACCAGAGAATAGTCAAAATAATCCTCCGCATCCA
GCTGATATTCATCCGGCATATCGAATTGGATATATGCAACTTCTACATACGCTTCATAAT
GCCACCAGCCCACAGTCTTCCTTACATGGTCCAGGTTTCTCGACCGAGAATCTTTCACAT
GCAGCTTCACTTGGTGTTCCATATTCAACACTCAACAGCTTTTCGAGTGATGTTAATATG
GAGCGACTAAAATCAAGCAATGGTGGTGCAACTCAGAGCTCATTAAGAGGTGATCCTATT
TCATGCTTTAACCGCAAACGTGCTCTCTCGTCATCACCATATCCTGATTTGCTTGATGTC
AGCACGGTGATTCGACATTCACCAAATTCACTATATGGATCAAAAAACAGTCATGTTAGT
GGTTCTTTTGGTCATCTCGCAGTAACAGCGTTGAACAATACCACAGCAAGTGCCACAAAT
GGCTCAATTGGTTCACCAATGTCAATTTCATCCCTGCCAACATCATTGCAACATTTTCTT
ATGAGCGGTGACATTCTACCTTCACTTTCGGGCCATTATATTTCGCCATCAAGTTCAATG
TTTTCGTTGGCTCATCATCAAGCTATGATGCAAGTCGATGCCTCGATGCAATCATTAAAA
TCGGAATCACTCGATGCTCAACAGAAGCACAATAATAGCAACAGTGCTAATTCATCAAAA
AGTGTAAACAATAAGAAAACTGATACAAATAACACGACAACAGTGACATCGGCAGAGGCT
GACAGTCCATCACAAATGCAATCGCAAATGCGTAGAGTAAAGATTAAAAGTGAAGCACAT
GATGATATTATACAAAATACGAAATTATCAACAACTAATTCACACTTAATGTCACATCAT
CATCATCATCAACATCAGCAGCAACAGCACAATCATTATAATAGTAACGCAAGTGCCAAT
GTAAATGAAAGTAACTTTAATAATCATCAACGACTGAAGCCAAATGGTATAATGAGTAAT
GTAGCAAATAACCACAAGAGCAAGGAAACGTTCAACGCCAAAAATAATAATAATAATCAT
AATCATAATAGTAATAGTAATCTAAGATCGAGTAATAATAACAGCAGCACGAGCAGTGAA
ACGGTTCTTGCTGACACGACCGATGCTAAGGATGATGGTGGCAATTTCTTTGAAACTAAT
TGTCATTGGAGAGGATGCGGACTGGAATTCCTGACGCAAGACGAATTGGTTCGTCATATT
AATACGGATCATATACATGGCAATAAAAAGTCCTTTGTGTGTCGATGGGAAACGTGCTCA
AGAGATGAAAAGCCATTTAAAGCACAATATATGCTTGTTGTTCATATGAGACGACATACA
GGAGAAAAGCCACACAAATGCACTTTTGAGGGCTGTCATAAAGCATATTCACGCTTAGAG
AATTTGAAAACACATCTTCGCAGTCATACTGGAGAAAAACCTTATACTTGCGAGTTTCCA
GGCTGTAGCAAGGCATTCAGTAATGCCTCGGATCGTGCAAAGCATCAGAATAGAACACAC
AGCAACGAGAAACCATACGTATGCAAAGCGCCAGGATGCACGAAACGCTATACTGATCCA
TCTAGTTTGAGAAAGCATGTGAAGACTGTACATGGAGCAGACTTTTATGCAAAGCGCAAG
CACAAGGGAACTGGTGATAGCGGAAGCGGTGAGGACGGCAATGGTGTTAGTAGTCCAGCT
ACAAATGACGACAGCTATAGCATTAAAACAACAAGTCTGATGAGTCCAAGTATAAAATCA
GAATCGGACATAAACTCGCCTGGTTATCCACAGATGAATAGTCCATCTGGCATCTCACAT
ATGAACGACATGAATGATGACTATGACTATAGTGGTGGCAATGGAGGTAACAATAACATG
AACAATGCCAACAGCACACAAATTGGCATAGTTTCATCAACCGTTGACTCACATTGGCCT
TATGAAGAAGAAGAAGAAACAGCTGAGGTTTCGGAGCTTCCAATGGTCTTACGTGCCATG
ATTGATTTTGATCAAAATAGTGTCGGTGGAGGTGGAGTGTCGTTAATGAATCCGGTTGAT
CAATTTAGTTCACGTTTTCGATCTCGTTTACACAATAAGGGTGGAATGCTTCAGCCACCA
TCACCCAATCCATCTGAATATATCAGCAGCTCATCACCACGTAGTAATTATGGAATAGGT
GAATTGAATCGTCGTATTACAGATCTAAAAGTGGACCATTCAGCACTCAGTCCACCTCAC
AATTTTATTGGGCACGATTCATCACCAAAATTACTCGAGCTTGGTCAAAATTTTCCAAAC
AATGGAACACCACCTTCAGCTCATTATCAACCAACAACATTGCACTATAATCAGCAAATT
AACCAACAAATTCGTCGTGATAGCAATAATTCAACGACAAGTAGCAGCTATTATAGCATG
AAATCATGCGATGTTAGTCGACGCAGTAGCAATCAGTCACATACTTCATCAATTTCAACA
TTAAGACCTAACTCGAATGTCGCTGCCAACTATAATAACAATAACTACGATGCAAATTTT
TTCTATGATCCTATTTCAGCTGGCAGCTCAAGACGTTCGAGTCAATTGTCGACAACTGAC
GGTAACTATGGACAACCGCCATCGTCTCAACTTTTATCCTCGCACTTGGCTCGTCTCCAA
CGTCATACTAATGCAGCTGTAGGACATCAATATGCCAACTCATCTTTTTATCAACAACAT
AATCAACCTTATAGTCTTTATAACTATCCACCAGCAGGCACATCTCAGAACAATGCTGCC
AGTGCTGTTAGAATGAATCAAATGTTCTACAACTATCCAAACATGAATGCTGCTGCCCAA
AACTACATGTATGGCAGCCGTCACCAAATGCCATCATCATCGACTGACAGACGAATGAGT
GAGCCGATTAGCAATGCTTCTCGAAATATTCAGAACGATTTCATTACAAGTCCAACAATT
CAACGACCTCGATCAACGACACCTACGAAATCATTAGAGATGCTTTTGGATAGTACAAAA
GAAATCACACCAACAAGTGAAAAATCTGCTGCTGCCGTCGCTGTTGTTGAGAAAGAAAGT
AACAGTAAAAATTCACCATCAAAACCTCATCCAAATGAAACAGTTGTACTTGATGTGCTA
AAAACGAACGAAAAAATCGAAAATTGCGATGAACTTGTCATACCTGATGAAATGATGCTG
TATTTGAATCAAGTTGGTGATGAGTTGCCTGCGAAGGCGGATGATGTAAAATCTACGGAT
CAATCGAAAATCAAATTGGATCTCAGTGAGACAGAGCTGATGTCATCGTCAATATCGATT
GAAAAGATTAAGGAGGAAGATTTGTTTACGCTGCTATCCGATGTGGAGGTGAAAAGAAAT
GATCAAAACGAAGCAAGCAATAATGATGTGGAGCAGCAACAAGAGCAAATTAATGATAAT
GAGATAGCTTCCGTGAATCCCATTGCGGATGATTACGAAATAAACAATAATAGCCAAGAT
GATTGCAAAATTGAAAGTGATACAAAAATCCATCAACAAATCCCGTGTAAATCGTAA
>g2857.t1 Gene=g2857 Length=1318
MKGPFGEVYPYHHHLHNQILNSASNGLFRSGGDINQLASQQQANAAASHFAASAANNNSL
HFPSAFVAFHNTQMAAAAAAAASGQQRSTHESNFNPASSFHYPHGPLFTEVQLLNSSSRN
SLVPVLPLSPENSQNNPPHPADIHPAYRIGYMQLLHTLHNATSPQSSLHGPGFSTENLSH
AASLGVPYSTLNSFSSDVNMERLKSSNGGATQSSLRGDPISCFNRKRALSSSPYPDLLDV
STVIRHSPNSLYGSKNSHVSGSFGHLAVTALNNTTASATNGSIGSPMSISSLPTSLQHFL
MSGDILPSLSGHYISPSSSMFSLAHHQAMMQVDASMQSLKSESLDAQQKHNNSNSANSSK
SVNNKKTDTNNTTTVTSAEADSPSQMQSQMRRVKIKSEAHDDIIQNTKLSTTNSHLMSHH
HHHQHQQQQHNHYNSNASANVNESNFNNHQRLKPNGIMSNVANNHKSKETFNAKNNNNNH
NHNSNSNLRSSNNNSSTSSETVLADTTDAKDDGGNFFETNCHWRGCGLEFLTQDELVRHI
NTDHIHGNKKSFVCRWETCSRDEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCHKAYSRLE
NLKTHLRSHTGEKPYTCEFPGCSKAFSNASDRAKHQNRTHSNEKPYVCKAPGCTKRYTDP
SSLRKHVKTVHGADFYAKRKHKGTGDSGSGEDGNGVSSPATNDDSYSIKTTSLMSPSIKS
ESDINSPGYPQMNSPSGISHMNDMNDDYDYSGGNGGNNNMNNANSTQIGIVSSTVDSHWP
YEEEEETAEVSELPMVLRAMIDFDQNSVGGGGVSLMNPVDQFSSRFRSRLHNKGGMLQPP
SPNPSEYISSSSPRSNYGIGELNRRITDLKVDHSALSPPHNFIGHDSSPKLLELGQNFPN
NGTPPSAHYQPTTLHYNQQINQQIRRDSNNSTTSSSYYSMKSCDVSRRSSNQSHTSSIST
LRPNSNVAANYNNNNYDANFFYDPISAGSSRRSSQLSTTDGNYGQPPSSQLLSSHLARLQ
RHTNAAVGHQYANSSFYQQHNQPYSLYNYPPAGTSQNNAASAVRMNQMFYNYPNMNAAAQ
NYMYGSRHQMPSSSTDRRMSEPISNASRNIQNDFITSPTIQRPRSTTPTKSLEMLLDSTK
EITPTSEKSAAAVAVVEKESNSKNSPSKPHPNETVVLDVLKTNEKIENCDELVIPDEMML
YLNQVGDELPAKADDVKSTDQSKIKLDLSETELMSSSISIEKIKEEDLFTLLSDVEVKRN
DQNEASNNDVEQQQEQINDNEIASVNPIADDYEINNNSQDDCKIESDTKIHQQIPCKS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g2857.t1 | Coils | Coil | Coil | 1260 | 1283 | - |
| 14 | g2857.t1 | Gene3D | G3DSA:3.30.160.60 | Classic Zinc Finger | 518 | 550 | 1.4E-13 |
| 12 | g2857.t1 | Gene3D | G3DSA:3.30.160.60 | Classic Zinc Finger | 551 | 580 | 9.5E-13 |
| 16 | g2857.t1 | Gene3D | G3DSA:3.30.160.60 | Classic Zinc Finger | 581 | 614 | 3.0E-12 |
| 13 | g2857.t1 | Gene3D | G3DSA:3.30.160.60 | Classic Zinc Finger | 615 | 643 | 3.7E-11 |
| 15 | g2857.t1 | Gene3D | G3DSA:3.30.160.60 | Classic Zinc Finger | 644 | 672 | 1.7E-13 |
| 29 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 336 | 402 | - |
| 30 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 336 | 392 | - |
| 28 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 476 | 502 | - |
| 34 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 678 | 728 | - |
| 32 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 690 | 728 | - |
| 31 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 833 | 855 | - |
| 27 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 838 | 855 | - |
| 35 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 925 | 961 | - |
| 33 | g2857.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 992 | 1013 | - |
| 5 | g2857.t1 | PANTHER | PTHR45718:SF4 | TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS | 47 | 391 | 2.0E-211 |
| 7 | g2857.t1 | PANTHER | PTHR45718 | TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS | 47 | 391 | 2.0E-211 |
| 6 | g2857.t1 | PANTHER | PTHR45718:SF4 | TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS | 387 | 1292 | 2.0E-211 |
| 8 | g2857.t1 | PANTHER | PTHR45718 | TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS | 387 | 1292 | 2.0E-211 |
| 2 | g2857.t1 | Pfam | PF00096 | Zinc finger, C2H2 type | 552 | 579 | 0.0015 |
| 4 | g2857.t1 | Pfam | PF00096 | Zinc finger, C2H2 type | 585 | 609 | 0.012 |
| 1 | g2857.t1 | Pfam | PF00096 | Zinc finger, C2H2 type | 615 | 640 | 0.011 |
| 3 | g2857.t1 | Pfam | PF00096 | Zinc finger, C2H2 type | 646 | 671 | 2.8E-4 |
| 21 | g2857.t1 | ProSitePatterns | PS00028 | Zinc finger C2H2 type domain signature. | 521 | 544 | - |
| 19 | g2857.t1 | ProSitePatterns | PS00028 | Zinc finger C2H2 type domain signature. | 587 | 609 | - |
| 20 | g2857.t1 | ProSitePatterns | PS00028 | Zinc finger C2H2 type domain signature. | 617 | 640 | - |
| 18 | g2857.t1 | ProSitePatterns | PS00028 | Zinc finger C2H2 type domain signature. | 648 | 671 | - |
| 38 | g2857.t1 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 519 | 551 | 8.995 |
| 39 | g2857.t1 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 557 | 584 | 10.575 |
| 37 | g2857.t1 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 585 | 614 | 14.482 |
| 36 | g2857.t1 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 615 | 645 | 13.962 |
| 40 | g2857.t1 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 646 | 671 | 9.91 |
| 26 | g2857.t1 | SMART | SM00355 | c2h2final6 | 519 | 544 | 0.12 |
| 23 | g2857.t1 | SMART | SM00355 | c2h2final6 | 552 | 579 | 4.3 |
| 25 | g2857.t1 | SMART | SM00355 | c2h2final6 | 585 | 609 | 0.0058 |
| 22 | g2857.t1 | SMART | SM00355 | c2h2final6 | 615 | 640 | 0.0062 |
| 24 | g2857.t1 | SMART | SM00355 | c2h2final6 | 646 | 671 | 9.2E-4 |
| 10 | g2857.t1 | SUPERFAMILY | SSF57667 | beta-beta-alpha zinc fingers | 519 | 548 | 3.23E-7 |
| 9 | g2857.t1 | SUPERFAMILY | SSF57667 | beta-beta-alpha zinc fingers | 566 | 623 | 1.62E-17 |
| 11 | g2857.t1 | SUPERFAMILY | SSF57667 | beta-beta-alpha zinc fingers | 626 | 673 | 4.97E-9 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006357 | regulation of transcription by RNA polymerase II | BP |
| GO:0005634 | nucleus | CC |
| GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | MF |
KEGG
Orthology
- This transcript has been annotated with K16799 (transcriptional activator cubitus interruptus)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
