General information for g2925.t16
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Hexokinase type 2.
Parent gene
- The parent gene g2925 is located on chr_3: 21273540..21284647 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2925 | g2925.t16 | TSS | g2925.t16 | 21264718 | 21264718 |
| chr_3 | g2925 | g2925.t16 | isoform | g2925.t16 | 21264957 | 21274282 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon1 | 21264957 | 21264995 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS1 | 21264957 | 21264995 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon2 | 21271023 | 21271185 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS2 | 21271023 | 21271185 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon3 | 21271251 | 21271435 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS3 | 21271251 | 21271435 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon4 | 21271497 | 21271670 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS4 | 21271497 | 21271670 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon5 | 21272698 | 21272797 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS5 | 21272698 | 21272797 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon6 | 21272950 | 21273142 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS6 | 21272950 | 21273142 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon7 | 21273203 | 21273542 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS7 | 21273203 | 21273542 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon8 | 21273600 | 21273666 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS8 | 21273600 | 21273666 |
| chr_3 | g2925 | g2925.t16 | exon | g2925.t16.exon9 | 21273883 | 21274282 |
| chr_3 | g2925 | g2925.t16 | cds | g2925.t16.CDS9 | 21273883 | 21273923 |
| chr_3 | g2925 | g2925.t16 | TTS | g2925.t16 | 21274517 | 21274517 |
Sequences
>g2925.t16 Gene=g2925 Length=1661
ATGTCCAAAGGTGTAGTAATGACTAAACCAACAAAAGAGATCAAGGAAGCCTGTCAGGAG
TTGATATTGGATGACAAAACAATGAGAGAAATCATGAAGAGATTTCTTCATGAAATTCAA
CTTGGGTTAAAGAAAGAGACACATCCAGCAGCTGACATTAAGTGCTTCATAACTTACGTT
CAAGATTTGCCAAATGGAAAAGAAAAAGGCAGATTCCTTGCATTGGATTTAGGTGGTACG
AATTTCCGTGTCCTTCTTATTCATCTCAAAGGTGACAGTGAGTTCGAAATGCAATCAAAG
ATTTACGCCATCCCACAAAGTATTATGATTGGTTCGGGAACACAATTGTTTGACCATATT
GCTGAATGTCTTGCAAATTTCATCAAGGAACATAAACTTCAAAATGAACGGCTGCCATTA
GGTTTTACTTTCTCCTTCCCTCTTAAACAGTTAGGTTTAACAAAGGGTATTTTAATCAGA
TGGACTAAAGGTTTCAATTGTGAGGGAGTTGTTGATCGTGATGTCGTTGAACTGTTAGAA
GAGGCATTAAAAAGACGTGGAGATGTTTCTATTGAAATTTGTGCTATTCTTAATGATACA
ACTGGAACTCTTATGTCATGTGCCTGGAAAAATCACAACTGTAAAATCGGAGCTATTGTT
GGTACTGGAAGTAATGCATGTTACGTAGAGCGTGTTGAGAATGCAGAACTTTACGATGGT
CCAGCAAATGGAAAAGAATATGTGTTGATCAATACAGAGTGGGGTGCTTTTGGTGACAAT
GGTGCTCTTGATTTTATTCGTACACAGTATGATCGGGAGATGGATGAATTTAGTATCAAT
AAAGGAAAACAGACAGTTGAAAAGATGATTTCGGGAATGTATATGGGTGAATTAGTGAGA
CTTGCACTTGTTAGATTCACAAAAGAAGGACTTTTGTTTGGTGGACAAGGATCTGATTTA
CTCTTCAAACGTTACCAATTTTTCACAAAATACGTGTCTGAAATTGAGAGCGATAAGCCT
GGAACTTTCTTTAATTGTTATGATGTGCTTGAGGAAATTGGAATTTTCCATGCCACTGAT
GAGGACTGTGCAAATGTGAGATATATTTGCGAGTGCATTTCAAGTCGTGCTGCTCATTTA
TCATCAGCTGGTATTGCCACGCTTATAAACAAAATGAATGATCCAAGTGTTACTGTCGGT
GTTGATGGATCTGTCTATCGTTTCCATCCTAAATTCCATGATTTAATGATGGTAAAAATT
CTGTTTAAATTTTATTGTTTTGTATTAGTTCTTAGTATGTAGTCGTATGCAATGTGGAGT
GCATGGATATTTTTGTAAAAAATCTCTTGTGAATCGCTCGATTTTGAGGTTGATGCAAAA
AAAATAAATTTTTTATTATTTATTATAATTTTTCTTGTCGTACTCTTCATTTCAAAACAA
GATCATACATATAGTTCCAACTGATAAAAAAATATTAAAATAACCTTTTAAAGAAGCAAT
AACTTTAACATCCAGCCGATTACAAAAAATTAAAAATCAAATGAAGAGGGCAGAATCAAA
AAAAAAAAAAGAGTGAATGTGGCAAAGCATTATATAAGAAGAGTGAAACTATGATTTTTA
TTAAACTGTAAGACTAGATTCTATAATTTAGTTGCTAGATA
>g2925.t16 Gene=g2925 Length=433
MSKGVVMTKPTKEIKEACQELILDDKTMREIMKRFLHEIQLGLKKETHPAADIKCFITYV
QDLPNGKEKGRFLALDLGGTNFRVLLIHLKGDSEFEMQSKIYAIPQSIMIGSGTQLFDHI
AECLANFIKEHKLQNERLPLGFTFSFPLKQLGLTKGILIRWTKGFNCEGVVDRDVVELLE
EALKRRGDVSIEICAILNDTTGTLMSCAWKNHNCKIGAIVGTGSNACYVERVENAELYDG
PANGKEYVLINTEWGAFGDNGALDFIRTQYDREMDEFSINKGKQTVEKMISGMYMGELVR
LALVRFTKEGLLFGGQGSDLLFKRYQFFTKYVSEIESDKPGTFFNCYDVLEEIGIFHATD
EDCANVRYICECISSRAAHLSSAGIATLINKMNDPSVTVGVDGSVYRFHPKFHDLMMVKI
LFKFYCFVLVLSM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g2925.t16 | CDD | cd00012 | NBD_sugar-kinase_HSP70_actin | 73 | 255 | 2.59809E-9 |
| 14 | g2925.t16 | Gene3D | G3DSA:3.40.367.20 | - | 19 | 417 | 2.9E-161 |
| 13 | g2925.t16 | Gene3D | G3DSA:3.30.420.40 | - | 58 | 209 | 2.9E-161 |
| 3 | g2925.t16 | PANTHER | PTHR19443:SF4 | HEXOKINASE-2 | 11 | 417 | 1.6E-162 |
| 4 | g2925.t16 | PANTHER | PTHR19443 | HEXOKINASE | 11 | 417 | 1.6E-162 |
| 8 | g2925.t16 | PRINTS | PR00475 | Hexokinase family signature | 73 | 89 | 9.7E-61 |
| 7 | g2925.t16 | PRINTS | PR00475 | Hexokinase family signature | 140 | 165 | 9.7E-61 |
| 5 | g2925.t16 | PRINTS | PR00475 | Hexokinase family signature | 193 | 209 | 9.7E-61 |
| 6 | g2925.t16 | PRINTS | PR00475 | Hexokinase family signature | 216 | 230 | 9.7E-61 |
| 10 | g2925.t16 | PRINTS | PR00475 | Hexokinase family signature | 284 | 306 | 9.7E-61 |
| 9 | g2925.t16 | PRINTS | PR00475 | Hexokinase family signature | 366 | 388 | 9.7E-61 |
| 2 | g2925.t16 | Pfam | PF00349 | Hexokinase | 14 | 209 | 4.9E-72 |
| 1 | g2925.t16 | Pfam | PF03727 | Hexokinase | 215 | 417 | 3.6E-72 |
| 16 | g2925.t16 | ProSitePatterns | PS00378 | Hexokinase domain signature. | 140 | 165 | - |
| 17 | g2925.t16 | ProSiteProfiles | PS51748 | Hexokinase domain profile. | 8 | 433 | 49.416 |
| 12 | g2925.t16 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 6 | 211 | 6.48E-78 |
| 11 | g2925.t16 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 213 | 417 | 3.17E-72 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0001678 | cellular glucose homeostasis | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0006096 | glycolytic process | BP |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0005536 | glucose binding | MF |
| GO:0004396 | hexokinase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00844 (hexokinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed