General information for g2925.t32
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Hexokinase type 2.
Parent gene
- The parent gene g2925 is located on chr_3: 21273540..21284647 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2925 | g2925.t32 | isoform | g2925.t32 | 21271021 | 21274480 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon1 | 21271021 | 21271185 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS1 | 21271065 | 21271185 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon2 | 21271251 | 21271435 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS2 | 21271251 | 21271435 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon3 | 21271497 | 21271670 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS3 | 21271497 | 21271670 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon4 | 21272698 | 21272797 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS4 | 21272698 | 21272797 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon5 | 21272950 | 21273142 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS5 | 21272950 | 21273142 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon6 | 21273203 | 21273542 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS6 | 21273203 | 21273542 |
| chr_3 | g2925 | g2925.t32 | exon | g2925.t32.exon7 | 21273600 | 21274480 |
| chr_3 | g2925 | g2925.t32 | cds | g2925.t32.CDS7 | 21273600 | 21273776 |
| chr_3 | g2925 | g2925.t32 | TTS | g2925.t32 | 21274517 | 21274517 |
| chr_3 | g2925 | g2925.t32 | TSS | g2925.t32 | NA | NA |
Sequences
>g2925.t32 Gene=g2925 Length=2038
AGATCAAGGAAGCCTGTCAGGAGTTGATATTGGATGACAAAACAATGAGAGAAATCATGA
AGAGATTTCTTCATGAAATTCAACTTGGGTTAAAGAAAGAGACACATCCAGCAGCTGACA
TTAAGTGCTTCATAACTTACGTTCAAGATTTGCCAAATGGAAAAGAAAAAGGCAGATTCC
TTGCATTGGATTTAGGTGGTACGAATTTCCGTGTCCTTCTTATTCATCTCAAAGGTGACA
GTGAGTTCGAAATGCAATCAAAGATTTACGCCATCCCACAAAGTATTATGATTGGTTCGG
GAACACAATTGTTTGACCATATTGCTGAATGTCTTGCAAATTTCATCAAGGAACATAAAC
TTCAAAATGAACGGCTGCCATTAGGTTTTACTTTCTCCTTCCCTCTTAAACAGTTAGGTT
TAACAAAGGGTATTTTAATCAGATGGACTAAAGGTTTCAATTGTGAGGGAGTTGTTGATC
GTGATGTCGTTGAACTGTTAGAAGAGGCATTAAAAAGACGTGGAGATGTTTCTATTGAAA
TTTGTGCTATTCTTAATGATACAACTGGAACTCTTATGTCATGTGCCTGGAAAAATCACA
ACTGTAAAATCGGAGCTATTGTTGGTACTGGAAGTAATGCATGTTACGTAGAGCGTGTTG
AGAATGCAGAACTTTACGATGGTCCAGCAAATGGAAAAGAATATGTGTTGATCAATACAG
AGTGGGGTGCTTTTGGTGACAATGGTGCTCTTGATTTTATTCGTACACAGTATGATCGGG
AGATGGATGAATTTAGTATCAATAAAGGAAAACAGACAGTTGAAAAGATGATTTCGGGAA
TGTATATGGGTGAATTAGTGAGACTTGCACTTGTTAGATTCACAAAAGAAGGACTTTTGT
TTGGTGGACAAGGATCTGATTTACTCTTCAAACGTTACCAATTTTTCACAAAATACGTGT
CTGAAATTGAGAGCGATAAGCCTGGAACTTTCTTTAATTGTTATGATGTGCTTGAGGAAA
TTGGAATTTTCCATGCCACTGATGAGGACTGTGCAAATGTGAGATATATTTGCGAGTGCA
TTTCAAGTCGTGCTGCTCATTTATCATCAGCTGGTATTGCCACGCTTATAAACAAAATGA
ATGATCCAAGTGTTACTGTCGGTGTTGATGGATCTGTCTATCGTTTCCATCCTAAATTCC
ATGATTTAATGATGGTAAAAATTCGTGAACTTGTTCATGATCACATTCAATTTGACATCA
TGCTGTCTGAAGATGGGTCTGGAAGAGGAGCTGCTCTTGTTGCTGCTGTTGCTTCACGTG
ATGCACATGAATAAGACTCTTATGTGTAATGAGAATCTTTAAACAAAATAACTCTCGAGA
CGAACAATTCTGAAACGGGAGTCTAAATCATTTTAATTTTTAGTTGTAAGAATCAAAAAG
TGTTTAAATTTTATTGTTTTGTATTAGTTCTTAGTATGTAGTCGTATGCAATGTGGAGTG
CATGGATATTTTTGTAAAAAATCTCTTGTGAATCGCTCGATTTTGAGGTTGATGCAAAAA
AAATAAATTTTTTATTATTTATTATAATTTTTCTTGTCGTACTCTTCATTTCAAAACAAG
ATCATACATATAGTTCCAACTGATAAAAAAATATTAAAATAACCTTTTAAAGAAGCAATA
ACTTTAACATCCAGCCGATTACAAAAAATTAAAAATCAAATGAAGAGGGCAGAATCAAAA
AAAAAAAAAGAGTGAATGTGGCAAAGCATTATATAAGAAGAGTGAAACTATGATTTTTAT
TAAACTGTAAGACTAGATTCTATAATTTAGTTGCTAGATAAAACACAAATTTAAAATTGT
GTAAAAAATTTTCATACAAATTCTATAGGCATGTTTATAAGTTTTTTTGTTGCTCTCCTG
TTATCATTTATATATCTATGTAATTTTAAACAATTGGATTTTTTTAAAATCAAACTCACT
TGTCTAAATTATAAACTGAAAATTTTCGTTTAATTTTGTTCTTTTTAATTAAAGGCAA
>g2925.t32 Gene=g2925 Length=429
MREIMKRFLHEIQLGLKKETHPAADIKCFITYVQDLPNGKEKGRFLALDLGGTNFRVLLI
HLKGDSEFEMQSKIYAIPQSIMIGSGTQLFDHIAECLANFIKEHKLQNERLPLGFTFSFP
LKQLGLTKGILIRWTKGFNCEGVVDRDVVELLEEALKRRGDVSIEICAILNDTTGTLMSC
AWKNHNCKIGAIVGTGSNACYVERVENAELYDGPANGKEYVLINTEWGAFGDNGALDFIR
TQYDREMDEFSINKGKQTVEKMISGMYMGELVRLALVRFTKEGLLFGGQGSDLLFKRYQF
FTKYVSEIESDKPGTFFNCYDVLEEIGIFHATDEDCANVRYICECISSRAAHLSSAGIAT
LINKMNDPSVTVGVDGSVYRFHPKFHDLMMVKIRELVHDHIQFDIMLSEDGSGRGAALVA
AVASRDAHE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g2925.t32 | CDD | cd00012 | NBD_sugar-kinase_HSP70_actin | 46 | 228 | 1.08287E-8 |
| 15 | g2925.t32 | Gene3D | G3DSA:3.40.367.20 | - | 1 | 409 | 1.3E-169 |
| 14 | g2925.t32 | Gene3D | G3DSA:3.30.420.40 | - | 31 | 419 | 1.3E-169 |
| 3 | g2925.t32 | PANTHER | PTHR19443:SF4 | HEXOKINASE-2 | 3 | 426 | 2.7E-173 |
| 4 | g2925.t32 | PANTHER | PTHR19443 | HEXOKINASE | 3 | 426 | 2.7E-173 |
| 5 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 46 | 62 | 1.5E-71 |
| 10 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 113 | 138 | 1.5E-71 |
| 7 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 166 | 182 | 1.5E-71 |
| 6 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 189 | 203 | 1.5E-71 |
| 9 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 257 | 279 | 1.5E-71 |
| 11 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 339 | 361 | 1.5E-71 |
| 8 | g2925.t32 | PRINTS | PR00475 | Hexokinase family signature | 406 | 422 | 1.5E-71 |
| 2 | g2925.t32 | Pfam | PF00349 | Hexokinase | 2 | 182 | 2.5E-68 |
| 1 | g2925.t32 | Pfam | PF03727 | Hexokinase | 188 | 422 | 4.0E-83 |
| 17 | g2925.t32 | ProSitePatterns | PS00378 | Hexokinase domain signature. | 113 | 138 | - |
| 18 | g2925.t32 | ProSiteProfiles | PS51748 | Hexokinase domain profile. | 1 | 421 | 51.844 |
| 12 | g2925.t32 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 1 | 184 | 6.82E-74 |
| 13 | g2925.t32 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 186 | 425 | 4.97E-84 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0001678 | cellular glucose homeostasis | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0006096 | glycolytic process | BP |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0005536 | glucose binding | MF |
| GO:0004396 | hexokinase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00844 (hexokinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
