General information for g2925.t36
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Hexokinase type 2.
Parent gene
- The parent gene g2925 is located on chr_3: 21273540..21284647 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2925 | g2925.t36 | isoform | g2925.t36 | 21271942 | 21274145 |
| chr_3 | g2925 | g2925.t36 | exon | g2925.t36.exon1 | 21271942 | 21272041 |
| chr_3 | g2925 | g2925.t36 | cds | g2925.t36.CDS1 | 21271960 | 21272041 |
| chr_3 | g2925 | g2925.t36 | exon | g2925.t36.exon2 | 21272950 | 21273142 |
| chr_3 | g2925 | g2925.t36 | cds | g2925.t36.CDS2 | 21272950 | 21273142 |
| chr_3 | g2925 | g2925.t36 | exon | g2925.t36.exon3 | 21273203 | 21273542 |
| chr_3 | g2925 | g2925.t36 | cds | g2925.t36.CDS3 | 21273203 | 21273542 |
| chr_3 | g2925 | g2925.t36 | exon | g2925.t36.exon4 | 21273600 | 21274145 |
| chr_3 | g2925 | g2925.t36 | cds | g2925.t36.CDS4 | 21273600 | 21273776 |
| chr_3 | g2925 | g2925.t36 | TTS | g2925.t36 | 21274517 | 21274517 |
| chr_3 | g2925 | g2925.t36 | TSS | g2925.t36 | NA | NA |
Sequences
>g2925.t36 Gene=g2925 Length=1179
GATGTAAGAATCGCGGTGATGGCAGTATTGAATGATTCAACGGGAACACTAATGTCATGT
GCGCACAAAAATCTAAATTGTAAAATTGGTGTTATCATTGGTACTGGAAGTAATGCATGT
TACGTAGAGCGTGTTGAGAATGCAGAACTTTACGATGGTCCAGCAAATGGAAAAGAATAT
GTGTTGATCAATACAGAGTGGGGTGCTTTTGGTGACAATGGTGCTCTTGATTTTATTCGT
ACACAGTATGATCGGGAGATGGATGAATTTAGTATCAATAAAGGAAAACAGACAGTTGAA
AAGATGATTTCGGGAATGTATATGGGTGAATTAGTGAGACTTGCACTTGTTAGATTCACA
AAAGAAGGACTTTTGTTTGGTGGACAAGGATCTGATTTACTCTTCAAACGTTACCAATTT
TTCACAAAATACGTGTCTGAAATTGAGAGCGATAAGCCTGGAACTTTCTTTAATTGTTAT
GATGTGCTTGAGGAAATTGGAATTTTCCATGCCACTGATGAGGACTGTGCAAATGTGAGA
TATATTTGCGAGTGCATTTCAAGTCGTGCTGCTCATTTATCATCAGCTGGTATTGCCACG
CTTATAAACAAAATGAATGATCCAAGTGTTACTGTCGGTGTTGATGGATCTGTCTATCGT
TTCCATCCTAAATTCCATGATTTAATGATGGTAAAAATTCGTGAACTTGTTCATGATCAC
ATTCAATTTGACATCATGCTGTCTGAAGATGGGTCTGGAAGAGGAGCTGCTCTTGTTGCT
GCTGTTGCTTCACGTGATGCACATGAATAAGACTCTTATGTGTAATGAGAATCTTTAAAC
AAAATAACTCTCGAGACGAACAATTCTGAAACGGGAGTCTAAATCATTTTAATTTTTAGT
TGTAAGAATCAAAAAGTGTTTAAATTTTATTGTTTTGTATTAGTTCTTAGTATGTAGTCG
TATGCAATGTGGAGTGCATGGATATTTTTGTAAAAAATCTCTTGTGAATCGCTCGATTTT
GAGGTTGATGCAAAAAAAATAAATTTTTTATTATTTATTATAATTTTTCTTGTCGTACTC
TTCATTTCAAAACAAGATCATACATATAGTTCCAACTGATAAAAAAATATTAAAATAACC
TTTTAAAGAAGCAATAACTTTAACATCCAGCCGATTACA
>g2925.t36 Gene=g2925 Length=263
MAVLNDSTGTLMSCAHKNLNCKIGVIIGTGSNACYVERVENAELYDGPANGKEYVLINTE
WGAFGDNGALDFIRTQYDREMDEFSINKGKQTVEKMISGMYMGELVRLALVRFTKEGLLF
GGQGSDLLFKRYQFFTKYVSEIESDKPGTFFNCYDVLEEIGIFHATDEDCANVRYICECI
SSRAAHLSSAGIATLINKMNDPSVTVGVDGSVYRFHPKFHDLMMVKIRELVHDHIQFDIM
LSEDGSGRGAALVAAVASRDAHE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g2925.t36 | Gene3D | G3DSA:3.40.367.20 | - | 6 | 263 | 0.000 |
| 2 | g2925.t36 | PANTHER | PTHR19443:SF33 | PHOSPHOTRANSFERASE | 2 | 261 | 0.000 |
| 3 | g2925.t36 | PANTHER | PTHR19443 | HEXOKINASE | 2 | 261 | 0.000 |
| 5 | g2925.t36 | PRINTS | PR00475 | Hexokinase family signature | 23 | 37 | 0.000 |
| 7 | g2925.t36 | PRINTS | PR00475 | Hexokinase family signature | 91 | 113 | 0.000 |
| 4 | g2925.t36 | PRINTS | PR00475 | Hexokinase family signature | 173 | 195 | 0.000 |
| 6 | g2925.t36 | PRINTS | PR00475 | Hexokinase family signature | 240 | 256 | 0.000 |
| 1 | g2925.t36 | Pfam | PF03727 | Hexokinase | 22 | 256 | 0.000 |
| 10 | g2925.t36 | ProSiteProfiles | PS51748 | Hexokinase domain profile. | 1 | 255 | 30.195 |
| 8 | g2925.t36 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 20 | 260 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0001678 | cellular glucose homeostasis | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0005536 | glucose binding | MF |
| GO:0004396 | hexokinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
