Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Hexokinase type 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2925 g2925.t7 TSS g2925.t7 21264718 21264718
chr_3 g2925 g2925.t7 isoform g2925.t7 21264957 21271671
chr_3 g2925 g2925.t7 exon g2925.t7.exon1 21264957 21264995
chr_3 g2925 g2925.t7 exon g2925.t7.exon2 21271023 21271180
chr_3 g2925 g2925.t7 cds g2925.t7.CDS1 21271177 21271180
chr_3 g2925 g2925.t7 exon g2925.t7.exon3 21271251 21271435
chr_3 g2925 g2925.t7 cds g2925.t7.CDS2 21271251 21271435
chr_3 g2925 g2925.t7 exon g2925.t7.exon4 21271497 21271671
chr_3 g2925 g2925.t7 cds g2925.t7.CDS3 21271497 21271670
chr_3 g2925 g2925.t7 TTS g2925.t7 NA NA

Sequences

>g2925.t7 Gene=g2925 Length=557
ATGTCCAAAGGTGTAGTAATGACTAAACCAACAAAAGAGATCAAGGAAGCCTGTCAGGAG
TTGATATTGGATGACAAAACAATGAGAGAAATCATGAAGAGATTTCTTCATGAAATTCAA
CTTGGGTTAAAGAAAGAGACACATCCAGCAGCTGACATTAAGTGCTTCATAACTTACGTT
CAAGATTTGCCAAATGGAAAAAGGCAGATTCCTTGCATTGGATTTAGGTGGTACGAATTT
CCGTGTCCTTCTTATTCATCTCAAAGGTGACAGTGAGTTCGAAATGCAATCAAAGATTTA
CGCCATCCCACAAAGTATTATGATTGGTTCGGGAACACAATTGTTTGACCATATTGCTGA
ATGTCTTGCAAATTTCATCAAGGAACATAAACTTCAAAATGAACGGCTGCCATTAGGTTT
TACTTTCTCCTTCCCTCTTAAACAGTTAGGTTTAACAAAGGGTATTTTAATCAGATGGAC
TAAAGGTTTCAATTGTGAGGGAGTTGTTGATCGTGATGTCGTTGAACTGTTAGAAGAGGC
ATTAAAAAGACGTGGAG

>g2925.t7 Gene=g2925 Length=121
MEKGRFLALDLGGTNFRVLLIHLKGDSEFEMQSKIYAIPQSIMIGSGTQLFDHIAECLAN
FIKEHKLQNERLPLGFTFSFPLKQLGLTKGILIRWTKGFNCEGVVDRDVVELLEEALKRR
G

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g2925.t7 CDD cd00012 NBD_sugar-kinase_HSP70_actin 7 95 3.43584E-6
7 g2925.t7 Gene3D G3DSA:3.30.420.40 - 2 121 2.1E-52
2 g2925.t7 PANTHER PTHR19443:SF4 HEXOKINASE-2 2 121 2.9E-55
3 g2925.t7 PANTHER PTHR19443 HEXOKINASE 2 121 2.9E-55
5 g2925.t7 PRINTS PR00475 Hexokinase family signature 7 23 2.6E-20
4 g2925.t7 PRINTS PR00475 Hexokinase family signature 74 99 2.6E-20
1 g2925.t7 Pfam PF00349 Hexokinase 2 121 4.1E-47
9 g2925.t7 ProSitePatterns PS00378 Hexokinase domain signature. 74 99 -
10 g2925.t7 ProSiteProfiles PS51748 Hexokinase domain profile. 1 121 17.925
6 g2925.t7 SUPERFAMILY SSF53067 Actin-like ATPase domain 1 121 4.54E-51

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0001678 cellular glucose homeostasis BP
GO:0005524 ATP binding MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0006096 glycolytic process BP
GO:0005975 carbohydrate metabolic process BP
GO:0005536 glucose binding MF
GO:0004396 hexokinase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed