General information for g2981.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose dehydrogenase.
Parent gene
- The parent gene g2981 is located on chr_3: 21713030..21715723 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2981 | g2981.t1 | isoform | g2981.t1 | 21713030 | 21715723 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon1 | 21713030 | 21713182 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS1 | 21713030 | 21713182 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon2 | 21713249 | 21713285 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS2 | 21713249 | 21713285 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon3 | 21713352 | 21713568 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS3 | 21713352 | 21713568 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon4 | 21713639 | 21713846 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS4 | 21713639 | 21713846 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon5 | 21713899 | 21714249 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS5 | 21713899 | 21714249 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon6 | 21714309 | 21714392 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS6 | 21714309 | 21714392 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon7 | 21714472 | 21714584 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS7 | 21714472 | 21714584 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon8 | 21714838 | 21714909 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS8 | 21714838 | 21714909 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon9 | 21714971 | 21715385 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS9 | 21714971 | 21715385 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon10 | 21715441 | 21715606 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS10 | 21715441 | 21715606 |
| chr_3 | g2981 | g2981.t1 | exon | g2981.t1.exon11 | 21715662 | 21715723 |
| chr_3 | g2981 | g2981.t1 | cds | g2981.t1.CDS11 | 21715662 | 21715723 |
| chr_3 | g2981 | g2981.t1 | TTS | g2981.t1 | 21716700 | 21716700 |
| chr_3 | g2981 | g2981.t1 | TSS | g2981.t1 | NA | NA |
Sequences
>g2981.t1 Gene=g2981 Length=1878
ATGTCAACAGCACTCGCACTTTTTTCAAGCATCGCCTCACTCACTGCTTCGCCTGTGACA
CTCCTTAGTATGATTCCAATCATTGCAATTGGCCTTAATTATTATCGTTATACTAGCGTT
GATCCTGAATCAGCACCAATTGATGCTCCTGTTCTAAGGAAGTACTATGATTTTATAGTG
GTAGGAGCGGGTTCAGCAGGTGCAGTTGTAGCGGCACGTTTAGCTGAAATTGATCAATGG
AATGTACTCCTTTTGGAAGCAGGTGGTGATGAAACAGAGGTCAGTGATGTACCTGCAATG
GCAGGCTTTTTACAGTTATCAGATTTAGATTGGAAATATAAAACAACACCAAGAGCTGAT
CGAGCTTTTTGTGCGGCAATGAAAAATGATCAATGTAATTGGCCAAGAGGAAAAGTTCTC
GGTGGTTGTAGTGTATTAAATGCAATGGTGTATGTTCGTGGTAACAGACGTGATTATGAT
TATTGGGAACAATTGGGAAATATAGGCTGGTCATTTAACGACGTATTACCTTATTTTACA
AAATCAGAAGACAATAGAAATCCTTATCTTGCTCGATCACCCTATCATGGATCTGGAGGA
CTGCTCACAGTTCAGGAAGCACCATGGAGAACACCATTATCATTGACATTTATCAAAGCC
ATGAAAGAACTTGGTTATGAGCATCGTGATATTAATGGTGAAGAACAAGTTGGCGCAATG
ATGACTCAATCAACAATGAGACGAGGCACACGATGTTCAACATCAAAAGCATTTTTGAGA
CCAATTAGATTAAAGAAAAATTTGCATGTAGCTAAATTTGCACAAGCAACAAAAGTTCTT
ATCGATCCAAAAACCAAACGTACATATGGTATAGAGTTCATGAGAAACAACAAACGTCAA
GTGGCGTATGCAACAAAGGAAGTTATTTTATCAGCTGGATCGTTAAATTCACCCCAATTA
ATGATGCTGTCTGGAATTGGACATGCACAACATCTACAAGAAATGGGCATTCCCGTCATC
TCGGATTTGCCCGTTGGCGATAATTTACAGGATCATATTGGACTTGGTGGTCTAACATTT
ATCGTAAACGAGCCAGTAACAGTAACAACAAAACGTTTTGCAACAGTTCCCAGTTTCATT
GAATATATAATGCATGAACGCGGACCAATGACTTTCCCTGGTATTGAGGGGCTCGCATTT
GTAAATACAAAATATGCAGATCCATCAGGATTATGGCCTGATATTCAATTCCATTTTGGT
CCGAGTTCAATAAACTCAGATGGTGGTATGCATATACGAAAAATTACAAATTTGAAGGAT
GTAGTTTACAATACTGTCTATAAGCCTTTGGAAAATTCTGAAACTTGGACAATTTTGCCT
CTGTTGCTGCGTCCAAAAAGCTCAGGTTGGATTAGATTACAGAGTCGTAATCCATTTATT
CAGCCGCGCATAGAGCCAAACTACTTTGCATTCAAAGAAGATATCGCTGTTTTGACTGAA
GGCATCAAAATTGCAATGAACGTATCAAGTACTCAAGCATTTCAACGTTATGGCTCAAGA
CCACACACGATTCCATTCCCAGAATGTCGACATATTCCTCTTTTCACTGATGAATATTGG
GAATGTGCTATGCGACAATTTACATTTACTATATATCATCCAACGGGTACTGCAAAAATG
GGCCCAAATTGGGATCCAACAGCTGTAGTTGATCATAGATTAAGAGTTTATGGTGTTTCG
GGACTTAGAGTGATTGATGCAAGTATTATGCCGACTATCGTCTCAGGAAATCCAAATGCC
CCTGTTATTATGATCGGTGAGAAAGGAGCTGATATGATAAAGGAAGACTGGGGCGCAATA
AAAATACACAGAAAATAA
>g2981.t1 Gene=g2981 Length=625
MSTALALFSSIASLTASPVTLLSMIPIIAIGLNYYRYTSVDPESAPIDAPVLRKYYDFIV
VGAGSAGAVVAARLAEIDQWNVLLLEAGGDETEVSDVPAMAGFLQLSDLDWKYKTTPRAD
RAFCAAMKNDQCNWPRGKVLGGCSVLNAMVYVRGNRRDYDYWEQLGNIGWSFNDVLPYFT
KSEDNRNPYLARSPYHGSGGLLTVQEAPWRTPLSLTFIKAMKELGYEHRDINGEEQVGAM
MTQSTMRRGTRCSTSKAFLRPIRLKKNLHVAKFAQATKVLIDPKTKRTYGIEFMRNNKRQ
VAYATKEVILSAGSLNSPQLMMLSGIGHAQHLQEMGIPVISDLPVGDNLQDHIGLGGLTF
IVNEPVTVTTKRFATVPSFIEYIMHERGPMTFPGIEGLAFVNTKYADPSGLWPDIQFHFG
PSSINSDGGMHIRKITNLKDVVYNTVYKPLENSETWTILPLLLRPKSSGWIRLQSRNPFI
QPRIEPNYFAFKEDIAVLTEGIKIAMNVSSTQAFQRYGSRPHTIPFPECRHIPLFTDEYW
ECAMRQFTFTIYHPTGTAKMGPNWDPTAVVDHRLRVYGVSGLRVIDASIMPTIVSGNPNA
PVIMIGEKGADMIKEDWGAIKIHRK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g2981.t1 | Gene3D | G3DSA:3.50.50.60 | - | 56 | 614 | 4.4E-189 |
| 9 | g2981.t1 | Gene3D | G3DSA:3.30.560.10 | Glucose Oxidase | 95 | 552 | 4.4E-189 |
| 3 | g2981.t1 | PANTHER | PTHR11552:SF155 | ECDYSONE OXIDASE-RELATED | 45 | 618 | 3.3E-275 |
| 4 | g2981.t1 | PANTHER | PTHR11552 | GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE | 45 | 618 | 3.3E-275 |
| 15 | g2981.t1 | PIRSF | PIRSF000137 | Alcohol_oxidase | 37 | 624 | 8.5E-156 |
| 1 | g2981.t1 | Pfam | PF00732 | GMC oxidoreductase | 56 | 353 | 2.5E-80 |
| 2 | g2981.t1 | Pfam | PF05199 | GMC oxidoreductase | 465 | 608 | 2.8E-38 |
| 11 | g2981.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 16 | - |
| 12 | g2981.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 13 | g2981.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 11 | - |
| 14 | g2981.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 12 | 16 | - |
| 10 | g2981.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 17 | 625 | - |
| 17 | g2981.t1 | ProSitePatterns | PS00624 | GMC oxidoreductases signature 2. | 313 | 327 | - |
| 6 | g2981.t1 | SUPERFAMILY | SSF51905 | FAD/NAD(P)-binding domain | 53 | 618 | 3.4E-81 |
| 5 | g2981.t1 | SUPERFAMILY | SSF54373 | FAD-linked reductases, C-terminal domain | 348 | 557 | 2.94E-46 |
| 7 | g2981.t1 | SignalP_EUK | SignalP-TM | SignalP-TM | 1 | 16 | - |
| 16 | g2981.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | MF |
| GO:0050660 | flavin adenine dinucleotide binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed