General information for g3372.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as AP-2 complex subunit alpha.
Parent gene
- The parent gene g3372 is located on chr_3: 24953761..24955498 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3372 | g3372.t3 | TTS | g3372.t3 | 24950597 | 24950597 |
| chr_3 | g3372 | g3372.t3 | isoform | g3372.t3 | 24950853 | 24951728 |
| chr_3 | g3372 | g3372.t3 | exon | g3372.t3.exon1 | 24950853 | 24950930 |
| chr_3 | g3372 | g3372.t3 | cds | g3372.t3.CDS1 | 24950853 | 24950930 |
| chr_3 | g3372 | g3372.t3 | exon | g3372.t3.exon2 | 24950993 | 24951197 |
| chr_3 | g3372 | g3372.t3 | cds | g3372.t3.CDS2 | 24950993 | 24951197 |
| chr_3 | g3372 | g3372.t3 | exon | g3372.t3.exon3 | 24951257 | 24951401 |
| chr_3 | g3372 | g3372.t3 | cds | g3372.t3.CDS3 | 24951257 | 24951401 |
| chr_3 | g3372 | g3372.t3 | exon | g3372.t3.exon4 | 24951460 | 24951728 |
| chr_3 | g3372 | g3372.t3 | cds | g3372.t3.CDS4 | 24951460 | 24951688 |
| chr_3 | g3372 | g3372.t3 | TSS | g3372.t3 | NA | NA |
Sequences
>g3372.t3 Gene=g3372 Length=697
ATTCTTGTTTAAAAACAATGGTGTTTTGTTTGAAAATGAAATGATTCAGATTGGTGTAAA
GAGCGAATTCAGACAAAATTTGGGAAGATTGGGATTGTTCTATGGCAATAAGACTCAAGT
GCCACTCACAAATTTCCAGCCCGTTTTACAGTGGAACACAGAAGATTCTAAAAATCTTAA
TGTACAAATAAAGGCAGTTGACTCAACTCTAGATGCTGGTGCACAAATTCAACAAATGTT
AACAGCTGAATGCATAGACAGCTATTCTGATTCTCCATCTTTACAATTGTCATTCCGATA
TAATGGTACACCACAAAGCTTCACTATCAAACTACCACTTACAGTAAATAAATTCTTCGA
ACCAACTGAAATGAACTCGGAATCATTTTTTGCAAGATGGAAAAATTTGGGAGGAGAAAA
ACAGCGTGCTCAAAAAGTTTTCAAAGCTCAACTTCCACTCGATTTGCCAGGTGCAAAAAA
CAAATTATCTGGCTTTGGTGTGCAACTTTTAGAAGGTATTGATCCTAATCCCGATAATAT
GGTGTGTGCTGGAATCATTCATACACAATCACATCAAGTTGGTTGTTTACTCAGATTAGA
ACCTAACAAACAGGCACAGATGTTCCGTTTGACAGTGAGAGCTAGTAAAGAACAAGTGAC
TAATGAAATATGCAATCTGCTTGTTGACCAATTTTAA
>g3372.t3 Gene=g3372 Length=218
MIQIGVKSEFRQNLGRLGLFYGNKTQVPLTNFQPVLQWNTEDSKNLNVQIKAVDSTLDAG
AQIQQMLTAECIDSYSDSPSLQLSFRYNGTPQSFTIKLPLTVNKFFEPTEMNSESFFARW
KNLGGEKQRAQKVFKAQLPLDLPGAKNKLSGFGVQLLEGIDPNPDNMVCAGIIHTQSHQV
GCLLRLEPNKQAQMFRLTVRASKEQVTNEICNLLVDQF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g3372.t3 | Gene3D | G3DSA:2.60.40.1230 | - | 1 | 105 | 0 |
| 9 | g3372.t3 | Gene3D | G3DSA:3.30.310.10 | - | 106 | 218 | 0 |
| 3 | g3372.t3 | PANTHER | PTHR22780:SF33 | AP-2 COMPLEX SUBUNIT ALPHA-1 | 1 | 185 | 0 |
| 4 | g3372.t3 | PANTHER | PTHR22780 | ADAPTIN, ALPHA/GAMMA/EPSILON | 1 | 185 | 0 |
| 1 | g3372.t3 | Pfam | PF02883 | Adaptin C-terminal domain | 2 | 93 | 0 |
| 2 | g3372.t3 | Pfam | PF02296 | Alpha adaptin AP2, C-terminal domain | 105 | 213 | 0 |
| 7 | g3372.t3 | SMART | SM00809 | alpha_adaptinc2 | 1 | 99 | 0 |
| 5 | g3372.t3 | SUPERFAMILY | SSF49348 | Clathrin adaptor appendage domain | 1 | 104 | 0 |
| 6 | g3372.t3 | SUPERFAMILY | SSF55711 | Subdomain of clathrin and coatomer appendage domain | 105 | 218 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006886 | intracellular protein transport | BP |
| GO:0030117 | membrane coat | CC |
| GO:0030131 | clathrin adaptor complex | CC |
| GO:0016192 | vesicle-mediated transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
