General information for g3380.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome non-ATPase regulatory subunit 2.
Parent gene
- The parent gene g3380 is located on chr_3: 24994152..24994990 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3380 | g3380.t5 | isoform | g3380.t5 | 24992298 | 24994152 |
| chr_3 | g3380 | g3380.t5 | exon | g3380.t5.exon1 | 24992298 | 24993341 |
| chr_3 | g3380 | g3380.t5 | cds | g3380.t5.CDS1 | 24992310 | 24993341 |
| chr_3 | g3380 | g3380.t5 | exon | g3380.t5.exon2 | 24993401 | 24993791 |
| chr_3 | g3380 | g3380.t5 | cds | g3380.t5.CDS2 | 24993401 | 24993791 |
| chr_3 | g3380 | g3380.t5 | exon | g3380.t5.exon3 | 24993851 | 24994152 |
| chr_3 | g3380 | g3380.t5 | cds | g3380.t5.CDS3 | 24993851 | 24994152 |
| chr_3 | g3380 | g3380.t5 | TTS | g3380.t5 | 24994243 | 24994243 |
| chr_3 | g3380 | g3380.t5 | TSS | g3380.t5 | NA | NA |
Sequences
>g3380.t5 Gene=g3380 Length=1737
GAATTAGATATCATGGAACCAAAGACACCAGAAGATGTCTACAAATCTCACTTAGACAAT
GCGAGAGCTCATTTTGGATCATCAAACATCGACTCTGCTCGTCAAAATTTAGCAGCAAGT
TTCGTAAATGGCTTTGTAAATGCTGGATTCGGTCAAGATAAATTGCTAATGGAAGATGGA
AATAAGTGGCTTTATAAAAACAAAGAACATGGCATGTTTAGTGCAACTGCTTCACTCGGT
TTGATTTTATTATGGGATGTTGATGGCGGTTTGACACCAATCGATAAATATTTGTATTCG
TCAGAAGATCATATTAAAGCTGGTGCATTGCTCGCTTGTGGTATTGTAAACTGTGGTGTA
AGAAATGAAGTAGATCCTGCATTGGCTTTATTATCCGATTACGTTTTGCATACAAATACT
ACAATGCGAATTGGATCAATTCTTGGACTTGGACTTGCTTATGCCGGATCGAATCGTACA
GATGTTATTGAACTCATTTCATCAACATTTAGCTCTGATAAACGAGGTGGTTTAACTAAT
GAAGTGTTGGGTATTGCTGCTTTATCACTTGGTTTGATTGCTGTTGGTAGCTGTAATCCT
GATGTGACTGAAAGATTGACTCAAATTATTCAAGAACGTACTGAGAGTGATTTTCGTGAT
ACATTCACGAAATTTTTGTTCCTTGGCTTAGGCCTTGTTTATTTGGGACGTCAAGAGGCA
TCTGAAGCTTGCATCGCTGCTTTAGCTGTAATTGATGAACCATACAAATCAACAGTTACT
ACAATGGTTGAAATTTGTGCATATGCAGGCACTGGAAATGTTTTAAAAATTCAGCATTTG
CTTCATATTTGTAGTGAACATTATGAACCATATACACCTGATACTAGTGACAAAAGCAAA
AAAGATCAAAATGAACAGCAGCAAAAAGAAGAACGCGAAAAGGATTTATCTCAATGTCAA
GCTGTAGCTGTTTTAGGTATTGCATTGATTGCTCTTGGTGAAGACATTGGTGCAGAAATG
GCTTTCCGATCATTTGGAAATTTGCTTCGTTATTGCGAACCAACAATCAGACGCGCTGTA
CCATTAGCATTAGGATTGATTTCTGTTTCTAATCCCAAATTAAATATTCTTGATACTTTG
AGTAAATTTTCACACGATAGTGATTCTGAAGTGGCTCATAATGCAATTTTTGCAATGGGA
TTAGTTGGTGCAGGAACAAATAATGCCCGTTTAGCATCAATGTTACGTCAACTTGCTCAG
TATCACGCAAAAGATCCTAATAATCTCTTCATGGTACGCATTGCACAAGGTTTGACTCAT
TTAGGAAAGGGTACTTTAACTCTCAGCCCATATCATAGTGACAGACAATTGATGAGTCCT
GTAGCATTAGCTGGATTAATGGCAACACTCGTTGCATTTTTAGATGTCAAAAATATTATC
TTGTCAAGATCACATTATCTTTTGTATACCTTAGCAACGGCGATGCAACCACGTATGTTG
GTTACATTCGATGAAAACTTAAACCCATTAACTGTTCCAGTGCGTGTCGGTGTTGCTGTT
GATGTCGTTGGTCAAGCTGGAAAACCAAAAACAATCACAGGTTTTCAAACTCACACGACA
CCTGTTTTATTGGCAATGGGCGAAAGAGCAGAACTTGCAACTGAAGAATACACCTCAGTA
ACACCTGTCATGGAAGGTTTCGTTATTCTTCAGAAAAATCCTAATTATAAACCATAA
>g3380.t5 Gene=g3380 Length=574
MEPKTPEDVYKSHLDNARAHFGSSNIDSARQNLAASFVNGFVNAGFGQDKLLMEDGNKWL
YKNKEHGMFSATASLGLILLWDVDGGLTPIDKYLYSSEDHIKAGALLACGIVNCGVRNEV
DPALALLSDYVLHTNTTMRIGSILGLGLAYAGSNRTDVIELISSTFSSDKRGGLTNEVLG
IAALSLGLIAVGSCNPDVTERLTQIIQERTESDFRDTFTKFLFLGLGLVYLGRQEASEAC
IAALAVIDEPYKSTVTTMVEICAYAGTGNVLKIQHLLHICSEHYEPYTPDTSDKSKKDQN
EQQQKEEREKDLSQCQAVAVLGIALIALGEDIGAEMAFRSFGNLLRYCEPTIRRAVPLAL
GLISVSNPKLNILDTLSKFSHDSDSEVAHNAIFAMGLVGAGTNNARLASMLRQLAQYHAK
DPNNLFMVRIAQGLTHLGKGTLTLSPYHSDRQLMSPVALAGLMATLVAFLDVKNIILSRS
HYLLYTLATAMQPRMLVTFDENLNPLTVPVRVGVAVDVVGQAGKPKTITGFQTHTTPVLL
AMGERAELATEEYTSVTPVMEGFVILQKNPNYKP
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g3380.t5 | Gene3D | G3DSA:1.25.10.10 | - | 19 | 473 | 3.7E-123 |
| 8 | g3380.t5 | MobiDBLite | mobidb-lite | consensus disorder prediction | 288 | 310 | - |
| 5 | g3380.t5 | PANTHER | PTHR10943 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT | 1 | 572 | 3.7E-286 |
| 6 | g3380.t5 | PANTHER | PTHR10943:SF11 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 | 1 | 572 | 3.7E-286 |
| 2 | g3380.t5 | Pfam | PF01851 | Proteasome/cyclosome repeat | 104 | 139 | 4.8E-8 |
| 3 | g3380.t5 | Pfam | PF01851 | Proteasome/cyclosome repeat | 141 | 168 | 2.2E-5 |
| 1 | g3380.t5 | Pfam | PF01851 | Proteasome/cyclosome repeat | 390 | 417 | 4.8E-5 |
| 4 | g3380.t5 | Pfam | PF18051 | 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal | 519 | 572 | 9.9E-32 |
| 11 | g3380.t5 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 452 | - |
| 12 | g3380.t5 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 453 | 472 | - |
| 10 | g3380.t5 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 473 | 574 | - |
| 7 | g3380.t5 | SUPERFAMILY | SSF48371 | ARM repeat | 64 | 442 | 1.34E-30 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000502 | proteasome complex | CC |
| GO:0042176 | regulation of protein catabolic process | BP |
| GO:0030234 | enzyme regulator activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
