General information for g3434.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Sodium-coupled monocarboxylate transporter 1.
Parent gene
- The parent gene g3434 is located on chr_3: 25417101..25418936 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3434 | g3434.t1 | TTS | g3434.t1 | 25415495 | 25415495 |
| chr_3 | g3434 | g3434.t1 | isoform | g3434.t1 | 25415651 | 25418936 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon1 | 25415651 | 25416112 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS1 | 25415651 | 25416112 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon2 | 25416168 | 25416657 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS2 | 25416168 | 25416657 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon3 | 25416767 | 25416864 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS3 | 25416767 | 25416864 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon4 | 25416926 | 25416968 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS4 | 25416926 | 25416968 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon5 | 25417087 | 25417240 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS5 | 25417087 | 25417240 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon6 | 25417302 | 25417370 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS6 | 25417302 | 25417370 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon7 | 25417431 | 25417482 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS7 | 25417431 | 25417482 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon8 | 25418366 | 25418431 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS8 | 25418366 | 25418431 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon9 | 25418495 | 25418654 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS9 | 25418495 | 25418654 |
| chr_3 | g3434 | g3434.t1 | exon | g3434.t1.exon10 | 25418716 | 25418936 |
| chr_3 | g3434 | g3434.t1 | cds | g3434.t1.CDS10 | 25418716 | 25418936 |
| chr_3 | g3434 | g3434.t1 | TSS | g3434.t1 | 25418987 | 25418987 |
Sequences
>g3434.t1 Gene=g3434 Length=1815
ATGGAGGGCATTAACGTTGACGACATTCGAATTTCGTTACAAAAGTTTGGTTGGCCAGAT
TATTTAATTTTTCTCTGCATGCTGCTTATTAGTGCTCTAATCGGCGTGTATTTCGGCTTT
ATTGAGAAAAAATCAAAAGGTGCTGGCGATGACGAGGTAAACTATTTAGTTGGAGGTCGA
AAGATGAAAATATTTCCCGTTGCGATGTCTCTGATTGCAAGCTTTATATCAGGCATTAGC
TTACTAGGTACTCCAACTGAGATCTACATTTATGGAATTTCATACTTTTATATAATGGGT
GGAATTATTATCACAGCATTTGTAATGATGACTGTGTATCTTCCAGTTTTTCATGATCTT
CAATTAACTAGCACATATGAGTACCTACAGACACGTTTCGATAGAAAAATGCGCTTATTT
GGCTGCATTCTTTTTATATTCTCGCAGATTGTGTGGTTGCCCATCGTTATATTTGTTCCT
GCATTAGCGCTTAATCATGTGTCTGGCATTGATGTACATTTGATAACACCATTAACGTGT
GTCTGCTGCATTTTCTATACATGTGTTGGTGGAATGAAAGCGGTGATTTACACAGATGTC
TTTCAATCGCTAATGATGTTTGGAGCAATGTTGTTAGTCATTATTAAAGGCACTTACGAT
ATAGGCGGATTGGATGTTGTGATTACGCGCAATGTCGCGAGTAAACGTATCGAAGCACCA
GACACATCATTTGACTTAACTGAACGCCATACAATATGGTCGTTGTGCATAGGAGGTTTT
GTATATTGGCTTAAAGCGAACGCAATCAGTCAAAATATGATTCAACGTTATTTATCATTG
CCAAGTTTAGCGGCAGCCAAAAGAGCACTATGGATCTTTATCTCTGGCGTTTTTATTTTA
CTGGCCATTTGCTCCTATTGTGGATTATTGATTTATGCAACCTACTTTGAATGTGACCCG
CTTACAACAAAACTAGTCAAAGCAAAAGATCAATTGCTACCGCTGCTTGTTATGGACATT
TTGGGTGAATATCCAGGATTAGTTGGCATGTTTGTCGCTGGAGTATTTTCTGCTGCACTC
TCGTCACTCTCAACGGGACTTAACAGTATGTCAGCAGTAATTTTAGAAGACTTCTTTAAA
CCATTCTCGAGAAAGCCACTGACCGATCGTCAGACCAAATACATCATGAGAAGTGTTGTA
GTGATTTTTGGTGGCATTTGTGTGGCATTAGTTTATGTAGTTGAACATTTGGGCTCCGTG
CTAATGCTCTCAATGTCGCTTGGCAGCATAGCACAAGGTCCACTGCTTGGTGTATTTACA
TGTGGTGTATTATTTCCATGGGTGACGGGAACTGGCGCATTGGTGGGCAGTGCAACAGCT
CTATCATTTATGACGTGGCTTTGCATCAGTGCTCAACGGGCGATCTCAACAGGCGAATTG
AAATTCAGTACTAAGGAAATTTCTACAAGTGGCTGCACTTACCATTTTATTGACGCAGAT
CCAATGAACATGTTAGCCATCAATACGACGGCAGTATCGATTCCAAACTACACGACATCG
GAGCCAACTGGTTTTCAAATTCATCACATTTCCTACATATGGTATACACTCGTTGGCAGC
GCAATTTGTATCATTGTTTCGCTAATCACGTCATATTTCACGGGACCTAATAATCCTACC
GACTTGAATCCGAATTTACTTGCACCATTTGTGCGAAAATTAATCACAGCAAGAAACACT
ACGACGACAATAACAGCGGCAGCATCAAAAAAGAAATCCATTTATCGTGGCCGCGATGAT
GAAAGTCAATTATGA
>g3434.t1 Gene=g3434 Length=604
MEGINVDDIRISLQKFGWPDYLIFLCMLLISALIGVYFGFIEKKSKGAGDDEVNYLVGGR
KMKIFPVAMSLIASFISGISLLGTPTEIYIYGISYFYIMGGIIITAFVMMTVYLPVFHDL
QLTSTYEYLQTRFDRKMRLFGCILFIFSQIVWLPIVIFVPALALNHVSGIDVHLITPLTC
VCCIFYTCVGGMKAVIYTDVFQSLMMFGAMLLVIIKGTYDIGGLDVVITRNVASKRIEAP
DTSFDLTERHTIWSLCIGGFVYWLKANAISQNMIQRYLSLPSLAAAKRALWIFISGVFIL
LAICSYCGLLIYATYFECDPLTTKLVKAKDQLLPLLVMDILGEYPGLVGMFVAGVFSAAL
SSLSTGLNSMSAVILEDFFKPFSRKPLTDRQTKYIMRSVVVIFGGICVALVYVVEHLGSV
LMLSMSLGSIAQGPLLGVFTCGVLFPWVTGTGALVGSATALSFMTWLCISAQRAISTGEL
KFSTKEISTSGCTYHFIDADPMNMLAINTTAVSIPNYTTSEPTGFQIHHISYIWYTLVGS
AICIIVSLITSYFTGPNNPTDLNPNLLAPFVRKLITARNTTTTITAAASKKKSIYRGRDD
ESQL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 30 | g3434.t1 | CDD | cd11492 | SLC5sbd_NIS-SMVT | 19 | 553 | 0.0 |
| 4 | g3434.t1 | Gene3D | G3DSA:1.20.1730.10 | - | 45 | 558 | 2.2E-111 |
| 2 | g3434.t1 | PANTHER | PTHR42985:SF33 | FI02094P | 13 | 590 | 1.2E-265 |
| 3 | g3434.t1 | PANTHER | PTHR42985 | SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER | 13 | 590 | 1.2E-265 |
| 1 | g3434.t1 | Pfam | PF00474 | Sodium:solute symporter family | 55 | 457 | 4.1E-39 |
| 13 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 20 | - |
| 19 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 41 | - |
| 10 | g3434.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 42 | 61 | - |
| 25 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 62 | 82 | - |
| 12 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 83 | 87 | - |
| 20 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 88 | 116 | - |
| 5 | g3434.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 117 | 136 | - |
| 28 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 137 | 164 | - |
| 16 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 165 | 169 | - |
| 23 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 170 | 189 | - |
| 9 | g3434.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 190 | 195 | - |
| 26 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 196 | 215 | - |
| 14 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 216 | 249 | - |
| 29 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 250 | 268 | - |
| 8 | g3434.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 269 | 288 | - |
| 24 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 289 | 315 | - |
| 17 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 316 | 346 | - |
| 18 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 347 | 374 | - |
| 6 | g3434.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 375 | 393 | - |
| 27 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 394 | 414 | - |
| 15 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 415 | 433 | - |
| 22 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 434 | 467 | - |
| 7 | g3434.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 468 | 531 | - |
| 21 | g3434.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 532 | 553 | - |
| 11 | g3434.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 554 | 604 | - |
| 43 | g3434.t1 | ProSiteProfiles | PS50283 | Sodium:solute symporter family profile. | 17 | 474 | 49.411 |
| 44 | g3434.t1 | TIGRFAM | TIGR00813 | sss: transporter, solute:sodium symporter (SSS) family | 55 | 458 | 4.4E-82 |
| 37 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 20 | 42 | - |
| 41 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 63 | 85 | - |
| 31 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 95 | 117 | - |
| 33 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 138 | 160 | - |
| 39 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 175 | 197 | - |
| 42 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 204 | 223 | - |
| 40 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 250 | 269 | - |
| 32 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 290 | 312 | - |
| 36 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 341 | 363 | - |
| 38 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 398 | 420 | - |
| 35 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 435 | 457 | - |
| 34 | g3434.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 532 | 554 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed