General information for g3537.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Metallophosphoesterase 1-like protein.
Parent gene
- The parent gene g3537 is located on chr_3: 26276779..26277704 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3537 | g3537.t1 | TSS | g3537.t1 | 26276161 | 26276161 |
| chr_3 | g3537 | g3537.t1 | isoform | g3537.t1 | 26276178 | 26277451 |
| chr_3 | g3537 | g3537.t1 | exon | g3537.t1.exon1 | 26276178 | 26276279 |
| chr_3 | g3537 | g3537.t1 | cds | g3537.t1.CDS1 | 26276178 | 26276279 |
| chr_3 | g3537 | g3537.t1 | exon | g3537.t1.exon2 | 26276343 | 26276476 |
| chr_3 | g3537 | g3537.t1 | cds | g3537.t1.CDS2 | 26276343 | 26276476 |
| chr_3 | g3537 | g3537.t1 | exon | g3537.t1.exon3 | 26276536 | 26277451 |
| chr_3 | g3537 | g3537.t1 | cds | g3537.t1.CDS3 | 26276536 | 26277451 |
| chr_3 | g3537 | g3537.t1 | TTS | g3537.t1 | 26277662 | 26277662 |
Sequences
>g3537.t1 Gene=g3537 Length=1152
ATGTTTAAAAGAATTTTTAAATTTTTTCTTAAACTTTTGCGTAATTTTATTGTGACTTTT
ATTTTTTGTGAATTTTTAATTTATTATGTTGTTATCTATCAGTGTAACTATAAAAGTGTT
GACAATGAAAACATCAACGATGGATTGAAAGCAATGATTCTCGCTGATACACATATGTTA
GGACCATTTAAAGGTCATCCATTTGATAGATTAAGACGTGAATGGCAAATGAAAAGATCA
TTTCAAACAGCAATGCAAATTTTTAAGCCTGATGTAGTATTTATTCTTGGTGATGTTTTT
GATGAAGGAAATTGGGTGAATGATAAGCAATATCAAGAATATGTTGATCGTTTTCATACT
CTCTTCTATGTACCTTCAACTACACGACTTTATGCTATCCTTGGCAATCATGATGTAAAT
TTTCATTATGCTATGCATCCACATTTAGTCAATCGTTTCAGTAAAGCTTTTAATTTTACA
TCAGGTGTTAATTTGATAAGAGAAAAAAAAGTGACAGCAGATGGTACGAAAAGAATAGTA
AATTTTGTAACAATCAATTCAATGGCAATGGAAGGAGATGAATGTTATTTGTGTCATCAA
GCTAAAGAAGCATTGAAGTCGATTGGAAAAAAGTTAGAAATTTTAAAACAAAAAAATCGT
CATAGTCCTCCTTTTGTGATGCAACATTTTCCAACGTACAGAAATTCTGATGAAAATTGC
ATTGAAATTGATTCAGAAAATACAGATATTACAGTTTATCGTGAAAAATGGGAAGTTTTG
TCGAAATCAGCTAGTGAATTTATTGCTAAAACTATTGAGCCTAGAGGATATTTCAGTGGA
CATACTCATCGGTATTGCATGTATGGAAATGATTATGGAATTTATGAACATACAATCGCA
TCATTTAATTGGCGCAATATTAATATGCCTTCATTTTTATTAGCTGTATTCACACCTGAT
GATTATTCAATTTCAAAATGTGATATGCCAAAAGAGACGACTGTCATTATTTGTTATATT
GTTGGTACAATTATGCCAATTATTTTTGCTATTATTAATTGTAAGTATCCAATGAGAAAT
TTAGTTCGGAATTTTCTAAGATTTTCCCTGATCAGGATTAAATTTAGTCCAGCTGCTGGA
CTTTCCGGCTAA
>g3537.t1 Gene=g3537 Length=383
MFKRIFKFFLKLLRNFIVTFIFCEFLIYYVVIYQCNYKSVDNENINDGLKAMILADTHML
GPFKGHPFDRLRREWQMKRSFQTAMQIFKPDVVFILGDVFDEGNWVNDKQYQEYVDRFHT
LFYVPSTTRLYAILGNHDVNFHYAMHPHLVNRFSKAFNFTSGVNLIREKKVTADGTKRIV
NFVTINSMAMEGDECYLCHQAKEALKSIGKKLEILKQKNRHSPPFVMQHFPTYRNSDENC
IEIDSENTDITVYREKWEVLSKSASEFIAKTIEPRGYFSGHTHRYCMYGNDYGIYEHTIA
SFNWRNINMPSFLLAVFTPDDYSISKCDMPKETTVIICYIVGTIMPIIFAIINCKYPMRN
LVRNFLRFSLIRIKFSPAAGLSG
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g3537.t1 | Coils | Coil | Coil | 198 | 218 | - |
| 7 | g3537.t1 | Gene3D | G3DSA:3.60.21.10 | - | 49 | 312 | 8.9E-18 |
| 2 | g3537.t1 | PANTHER | PTHR13315:SF0 | METALLOPHOSPHOESTERASE 1 | 16 | 351 | 1.4E-90 |
| 3 | g3537.t1 | PANTHER | PTHR13315 | METALLO PHOSPHOESTERASE RELATED | 16 | 351 | 1.4E-90 |
| 1 | g3537.t1 | Pfam | PF00149 | Calcineurin-like phosphoesterase | 50 | 285 | 5.2E-15 |
| 10 | g3537.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 11 | - |
| 13 | g3537.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 31 | - |
| 11 | g3537.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 32 | 333 | - |
| 12 | g3537.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 334 | 354 | - |
| 9 | g3537.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 355 | 383 | - |
| 6 | g3537.t1 | SUPERFAMILY | SSF56300 | Metallo-dependent phosphatases | 48 | 333 | 1.05E-29 |
| 4 | g3537.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 34 | - |
| 5 | g3537.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 332 | 354 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006506 | GPI anchor biosynthetic process | BP |
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K23362 (ethanolamine phosphate phosphodiesterase [EC:3.1.-.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
