General information for g3543.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione S-transferase 1-1.
Parent gene
- The parent gene g3543 is located on chr_3: 26292687..26295776 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3543 | g3543.t1 | TTS | g3543.t1 | 26291404 | 26291404 |
| chr_3 | g3543 | g3543.t1 | isoform | g3543.t1 | 26292341 | 26293177 |
| chr_3 | g3543 | g3543.t1 | exon | g3543.t1.exon1 | 26292341 | 26292493 |
| chr_3 | g3543 | g3543.t1 | cds | g3543.t1.CDS1 | 26292341 | 26292493 |
| chr_3 | g3543 | g3543.t1 | exon | g3543.t1.exon2 | 26292546 | 26292713 |
| chr_3 | g3543 | g3543.t1 | cds | g3543.t1.CDS2 | 26292546 | 26292713 |
| chr_3 | g3543 | g3543.t1 | exon | g3543.t1.exon3 | 26292772 | 26293069 |
| chr_3 | g3543 | g3543.t1 | cds | g3543.t1.CDS3 | 26292772 | 26293069 |
| chr_3 | g3543 | g3543.t1 | exon | g3543.t1.exon4 | 26293128 | 26293177 |
| chr_3 | g3543 | g3543.t1 | cds | g3543.t1.CDS4 | 26293128 | 26293177 |
| chr_3 | g3543 | g3543.t1 | TSS | g3543.t1 | 26293227 | 26293227 |
Sequences
>g3543.t1 Gene=g3543 Length=669
ATGTCTTCAAAATTGGTTCTTTACTATTTGAGTGGATCTATGCCATCTAGAGCATGCATG
CTTCTTGCAAGACTCTTGAACTTAAATTTTGAAATTAAACAAGTTAATATTCCAAATAAT
GAACAATTTAATGAAGATTTTGTCAAGTTAAATCCTGCGAAAAAAATTCCTGTTTTAGTT
GATGGAGATTATGTGTTGAGTGAATCACGAGCAATACTCGCTTATTTAGTTAATTCACGC
AGTCCAGGAAGTAATTTATATCCAACAGATCCAAAACAAAGAGGAATTGTTGATCAACGA
TTATATTATGATGCAACAGTGTTTTTACCTAACATGCTTGCTGTCATTAGACCAATTGTC
GTCGAAAAAAAAACAGAAATTTCTCCAACTCTTCAAAAACCGATTGAAGAATCGCTTGAA
ATGATTGAGAGATATTTGAATGAATATGAATATGTTGCAGCATCACATTTAACAATCGCA
GATATTTCTATGCTTCCATCAGTCACAACAGCTAGAGAATTTGGATTTAATTTAACAAAA
TATCCCCGTCTCAATAAATGGCATCATAAACTTGAAACTTTACCAGGATTTGATGAGAAT
CTTTATGGATCAAAAACTAACGCAGCTTATCTGCGAAAAATGGTTAATGGACCTATCTTT
AATTTTTAA
>g3543.t1 Gene=g3543 Length=222
MSSKLVLYYLSGSMPSRACMLLARLLNLNFEIKQVNIPNNEQFNEDFVKLNPAKKIPVLV
DGDYVLSESRAILAYLVNSRSPGSNLYPTDPKQRGIVDQRLYYDATVFLPNMLAVIRPIV
VEKKTEISPTLQKPIEESLEMIERYLNEYEYVAASHLTIADISMLPSVTTAREFGFNLTK
YPRLNKWHHKLETLPGFDENLYGSKTNAAYLRKMVNGPIFNF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g3543.t1 | CDD | cd03177 | GST_C_Delta_Epsilon | 92 | 199 | 9.35345E-33 |
| 7 | g3543.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 79 | 1.2E-22 |
| 6 | g3543.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 83 | 218 | 9.7E-36 |
| 3 | g3543.t1 | PANTHER | PTHR43969 | GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED | 4 | 205 | 4.5E-55 |
| 2 | g3543.t1 | Pfam | PF02798 | Glutathione S-transferase, N-terminal domain | 6 | 77 | 7.2E-16 |
| 1 | g3543.t1 | Pfam | PF00043 | Glutathione S-transferase, C-terminal domain | 119 | 195 | 4.4E-9 |
| 9 | g3543.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 10 | g3543.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 26 | - |
| 8 | g3543.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 27 | 222 | - |
| 13 | g3543.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 3 | 84 | 22.006 |
| 12 | g3543.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 90 | 211 | 17.507 |
| 14 | g3543.t1 | SFLD | SFLDG01153 | Main.4: Theta-like | 4 | 212 | 0.0 |
| 15 | g3543.t1 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 4 | 212 | 0.0 |
| 4 | g3543.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 4 | 88 | 1.79E-22 |
| 5 | g3543.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 82 | 202 | 6.96E-26 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
