General information for g3557.t11
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as OTU domain-containing protein 5.
Parent gene
- The parent gene g3557 is located on chr_3: 26425801..26426126 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3557 | g3557.t11 | TSS | g3557.t11 | 26422154 | 26422154 |
| chr_3 | g3557 | g3557.t11 | isoform | g3557.t11 | 26422831 | 26426126 |
| chr_3 | g3557 | g3557.t11 | exon | g3557.t11.exon1 | 26422831 | 26422839 |
| chr_3 | g3557 | g3557.t11 | exon | g3557.t11.exon2 | 26424345 | 26424997 |
| chr_3 | g3557 | g3557.t11 | cds | g3557.t11.CDS1 | 26424790 | 26424997 |
| chr_3 | g3557 | g3557.t11 | exon | g3557.t11.exon3 | 26425061 | 26425249 |
| chr_3 | g3557 | g3557.t11 | cds | g3557.t11.CDS2 | 26425061 | 26425249 |
| chr_3 | g3557 | g3557.t11 | exon | g3557.t11.exon4 | 26425323 | 26425737 |
| chr_3 | g3557 | g3557.t11 | cds | g3557.t11.CDS3 | 26425323 | 26425737 |
| chr_3 | g3557 | g3557.t11 | exon | g3557.t11.exon5 | 26425793 | 26425956 |
| chr_3 | g3557 | g3557.t11 | cds | g3557.t11.CDS4 | 26425793 | 26425956 |
| chr_3 | g3557 | g3557.t11 | exon | g3557.t11.exon6 | 26426014 | 26426126 |
| chr_3 | g3557 | g3557.t11 | cds | g3557.t11.CDS5 | 26426014 | 26426126 |
| chr_3 | g3557 | g3557.t11 | TTS | g3557.t11 | 26426198 | 26426198 |
Sequences
>g3557.t11 Gene=g3557 Length=1543
TAGTAAAAGTCATGGGCGCTCCAGTAAACGTGAAAAGGCGGCAAATGGGGTACAAGTTCA
AACAAAATATCATCAGCCTCATGCCTCATCATCATCTTCCACTGCAGCAACGAGTGTAAA
TAAAAAGCAACAACTGCCTTGTCCAACAAACGTTGTATCATGCGTCACACAGCAGCAAAG
TCAACTGCACAGTGTCAGCACATCGACTGCCGTTGCTGAATGTTCTAAAAGTGATAACAA
TATAGCTGGCAATAGCTGTGTGAACAAGAAAATCAATGATCAAGAATGTAATGATGACTT
TTTAAAAATTCTCGAAGAAAAAGTATCTGGCTATAATAGCGGTGATGAGCATTTGGAATC
AAAAGAAAATCACTTGACTAATGATGAATGGAAAAGTCGTGATGAAAAATTTTCAACACT
ACTTGAATCTGAACGAGGTTTGATAATTAAAAACATGGAAGAAGATGGTGCATGCCTTTT
TAGGGCAATATCTTATCAAATTTACGGTGATCAAGACATGCACGATATCATAAGACAACA
AACTATGGATTATATCTATCAGAATCGTGAATATTTTGAACAATTTCTAACTGAGGACAT
TCACTCATATGTTAAACGTAAAAGACAAAACCATCTGCATGGCAACCATATAGAAATTCA
AGCAATGTCAGAAATGTACAATAGACCCGTCGAATTGTATTGTTATGAGCTGGCGCCTTT
AAATATATATAATCCAGAACAAATTAATAATGGTTACGATCCTTTACGACTATCATACCA
GAGGAATTGCCATTATAATGCGATATTAGATCCTTATAAGTCATCTGTTGGAGTTGGCTT
AGGATTAGCAGGATATCGACCAGAAGATTTTGATCCTGCTAAACAAGTAAAAGAAGCAGT
TCAAATGAGTGAACAATTAGAAATTGAACAGATGATGGTAGAGGATAAAATGAAAGTAAC
GGATTGGGAAGCGACAAACGAAGTAGTAGTTGAACAGATAGCGCGACAATCGTATTTGCA
ATTTTGTAAAGAGAGTATGCATAAGACATTTAAGAAAACAAGTACAATTACAAGCACCGC
TACAACTGAAGCTAGCGGAAGTTCTAGTTCTTCTAGTTCAATGTGTGATACATCAAGTAA
TGATCATCAGCAAGGATCTTCAACAACATTAAATCATTATGAGAGACAAAAGAGTCCTAG
TTATGTAGACAATTATTATATGCAACAACATAACAACACTGGAAGACGAAAGAAACGAGA
GAAAGGCGAGAAACGTAAGCAAGAGGAAGATGGATCAACAAGTTCAAAACGCGCAAAACG
ATCAAATTCACCTCAAAGTTCCTCATCATCAATATCGGGTGAAAGTGACAGCGATAAGCC
TGTATCTGCATTTTATCAATCTTTATTAGAATCATCGTATGCATCCGATGGACTTGGTCA
ATTAAGTGAACAAGAAATGATGCAAAAAGCGCTGATTCAATCGATTCAAGAAGTTGCAAA
AATAGGCAAAAATAATACAGATGACGAATACGATTCTCCATAA
>g3557.t11 Gene=g3557 Length=362
MEEDGACLFRAISYQIYGDQDMHDIIRQQTMDYIYQNREYFEQFLTEDIHSYVKRKRQNH
LHGNHIEIQAMSEMYNRPVELYCYELAPLNIYNPEQINNGYDPLRLSYQRNCHYNAILDP
YKSSVGVGLGLAGYRPEDFDPAKQVKEAVQMSEQLEIEQMMVEDKMKVTDWEATNEVVVE
QIARQSYLQFCKESMHKTFKKTSTITSTATTEASGSSSSSSSMCDTSSNDHQQGSSTTLN
HYERQKSPSYVDNYYMQQHNNTGRRKKREKGEKRKQEEDGSTSSKRAKRSNSPQSSSSSI
SGESDSDKPVSAFYQSLLESSYASDGLGQLSEQEMMQKALIQSIQEVAKIGKNNTDDEYD
SP
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g3557.t11 | Gene3D | G3DSA:1.10.10.1640 | - | 4 | 72 | 2.3E-31 |
| 9 | g3557.t11 | Gene3D | G3DSA:3.30.200.90 | - | 73 | 130 | 4.3E-17 |
| 8 | g3557.t11 | MobiDBLite | mobidb-lite | consensus disorder prediction | 203 | 241 | - |
| 7 | g3557.t11 | MobiDBLite | mobidb-lite | consensus disorder prediction | 258 | 309 | - |
| 6 | g3557.t11 | MobiDBLite | mobidb-lite | consensus disorder prediction | 271 | 285 | - |
| 5 | g3557.t11 | MobiDBLite | mobidb-lite | consensus disorder prediction | 286 | 309 | - |
| 2 | g3557.t11 | PANTHER | PTHR12419:SF4 | OTU DOMAIN-CONTAINING PROTEIN 5 | 1 | 234 | 1.3E-82 |
| 3 | g3557.t11 | PANTHER | PTHR12419 | OTU DOMAIN CONTAINING PROTEIN | 1 | 234 | 1.3E-82 |
| 1 | g3557.t11 | Pfam | PF02338 | OTU-like cysteine protease | 4 | 92 | 2.1E-14 |
| 11 | g3557.t11 | ProSiteProfiles | PS50802 | OTU domain profile. | 1 | 120 | 15.426 |
| 4 | g3557.t11 | SUPERFAMILY | SSF54001 | Cysteine proteinases | 1 | 121 | 4.32E-32 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004843 | thiol-dependent deubiquitinase | MF |
| GO:0016579 | protein deubiquitination | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
