General information for g3606.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Endoplasmin.
Parent gene
- The parent gene g3606 is located on chr_3: 26728052..26728757 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3606 | g3606.t1 | TTS | g3606.t1 | 26725832 | 26725832 |
| chr_3 | g3606 | g3606.t1 | isoform | g3606.t1 | 26726004 | 26728757 |
| chr_3 | g3606 | g3606.t1 | exon | g3606.t1.exon1 | 26726004 | 26727799 |
| chr_3 | g3606 | g3606.t1 | cds | g3606.t1.CDS1 | 26726004 | 26727799 |
| chr_3 | g3606 | g3606.t1 | exon | g3606.t1.exon2 | 26727861 | 26727983 |
| chr_3 | g3606 | g3606.t1 | cds | g3606.t1.CDS2 | 26727861 | 26727983 |
| chr_3 | g3606 | g3606.t1 | exon | g3606.t1.exon3 | 26728049 | 26728283 |
| chr_3 | g3606 | g3606.t1 | cds | g3606.t1.CDS3 | 26728049 | 26728283 |
| chr_3 | g3606 | g3606.t1 | exon | g3606.t1.exon4 | 26728428 | 26728594 |
| chr_3 | g3606 | g3606.t1 | cds | g3606.t1.CDS4 | 26728428 | 26728594 |
| chr_3 | g3606 | g3606.t1 | exon | g3606.t1.exon5 | 26728706 | 26728757 |
| chr_3 | g3606 | g3606.t1 | cds | g3606.t1.CDS5 | 26728706 | 26728757 |
| chr_3 | g3606 | g3606.t1 | TSS | g3606.t1 | 26728851 | 26728851 |
Sequences
>g3606.t1 Gene=g3606 Length=2373
ATGAAGTATTTATTAGCCACGACTCTTGGCATAGTACTATTGATTTCTACAGGCATCCTT
GTTAGTGGATCAAAAGATCAAGATGGTGTGGACGATGTTAAAATAGATGCTACACTTAAG
ACATCAACTGGTACAGATTCGGAAACATTAAAGCGTGAAGAAGAATCAATTAATATTGAT
GGCTTGAGTCAGAAAGAACTTAAAGATTTAAGAGACAAGGCTGAAAAACACACTTTCCAA
GCTGAAGTTAATCGAATGATGAAACTTATCATTAATTCACTTTACAAAAATAAAGAAATT
TTCTTGCGTGAATTAATATCCAATGCGAGTGATGCTCTCGATAAAATTCGTTTGATGTCT
TTGACAGACCGCGCACAATTGGAAACCAATACGGATTTGATTATTCGAGTTAAAACTGAT
AAGGAAAATCGTGTTCTACATATCATTGATACTGGAATCGGAATGACTCACGATGACTTA
ATCAACAATCTTGGTACAATTGCAAAATCTGGAACAGCTGATTTCTTATCGAAGGTACAA
GAAAATGAAAATGGTCAAGATGCTAATGATATGATCGGTCAATTTGGTGTTGGATTTTAT
TCTGCTTTCTTGGTCGCCGACAAAGTAGTTGTCACAACAAAACATAATGATGATGAACAA
TATATTTGGGAAAGTGATTCTGCCAATTTCAATATTGTAAAAGATCCACGCGGAAGTACA
CTCAAACGTGGCTCACAAATCTCATTATATTTGAAAGAAGAGGCTCAAGATTTTTTGGAA
GAAGATACTATTAAACAATTAATCAAAAAGTATTCACAGTTCATCAATTTCCCAATTTAT
ATGTGGACATCAAAAACTGTAGAAGAAGAAGTACCAATTGAAGAAGAAATTGAAAAGAAG
GAAGCTGAAGATGAAACAGATGACGATGAGGCCAAAGTTGAGGAAGAAGCACCTGAAGAA
AAAACTCCAAAAACTAAGAAACAAACTAAAACTGTCTGGGATTGGGAACTTATGAACGAT
AGTAAACCAATTTGGACACGTAAACCCGCTGATGTCACACAAGACGAATACGATGCATTC
TATAAAAGTTTAACTAAAGACACATCGGAACCACTTACACAAACACATTTTGTTGCTGAA
GGCGAAGTCACATTCAAATCTCTTTTATTTGTACCAAAAATTCAGCCATCTGAAAGTTTC
AACAAATATGGTTCAAAATCAGATAATATTAAATTATATGTTCGACGTGTTTTCATCACA
GATGAATTTAATGATTTAATGCCCAATTATTTAGGATTCATTCGTGGTGTTGTAGATTCA
GATGATTTGCCATTAAATGTTTCTCGTGAGACTTTACAACAACATAAACTGATTAAAGTC
ATCAAGAAGAAATTAGTAAGAAAAGCTCTTGACATGTTGAAAAAATTGGAAGGTGAAGAA
TATGATAAATTCTGGAAAGAATATTCAACAAATATCAAACTTGGAGTAATGGAGGACTCG
AGCAATCGCGCTCGCTTAGCAAAATTATTGAAATTCCAATCATCAAATACAAAGAGTGGA
AAATTAACATCACTCTCCGACTATTCGAGCCGAATGAAACCAAAGCAAGAATGGATTTAT
TATATTGCTGCCGCTTCTCGTGCTGAAGCTGAAAAATCACCTTTCATTGAACGTTTAGTT
GCTCGCGGTTATGAAGTATTATTCTTAGTCGAAGCTGTTGATGAATATTGCATTTCTGCT
TTACCTGAATTTGATGGTAAAAAGTTCCAAAATGTTGCCAAAGAAGGTTTCTCTCTACCA
GAATCTGAAGAAGCCAAGGAGAAATTTGAAGAGCTTAAGAACAAATTTGAGCCATTGGCT
AAGTGGTTTGCAGATGTTGGTTTAAAGGATAAAATTACAAAAGCTATGGTTTCAGAGAAA
TTAACAAATACCCCATGTGTGCTTGTCGCATCAATGTTTGGTTGGACTGGAAATATGGAA
CGTCTTGCAATGTCAAATGCACATAAGAAAGCTGAAGATGTTTCACAATCGTACTATTTT
AATCAAAAGAAAGCTCTCGAATTCAATCCACGTCATCCTGTCATCAAAGATCTCCTAAGA
AAGATTGATGCCGATCCACAAGACCCGTCTGCTAAGGAAATGGCAGAACTTTTATTGGAC
ACGGCTGTCCTTCGTTCAGGCTTTATGCTCACAGAAACGAGAAAATTTGCAGATAGTATT
GATAAACTTATGAGACAAGCAATGAATCTTCAAGATGCAGAATTTGATCCCGAAATCGAA
GAATTCCCAGAACCATCAAATACTGATGAGCCACAGACTGATGCAGATGAAGAGGAAATA
GATGGAGATTTAGAAGAGCATGACGAGCTCTAA
>g3606.t1 Gene=g3606 Length=790
MKYLLATTLGIVLLISTGILVSGSKDQDGVDDVKIDATLKTSTGTDSETLKREEESINID
GLSQKELKDLRDKAEKHTFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMS
LTDRAQLETNTDLIIRVKTDKENRVLHIIDTGIGMTHDDLINNLGTIAKSGTADFLSKVQ
ENENGQDANDMIGQFGVGFYSAFLVADKVVVTTKHNDDEQYIWESDSANFNIVKDPRGST
LKRGSQISLYLKEEAQDFLEEDTIKQLIKKYSQFINFPIYMWTSKTVEEEVPIEEEIEKK
EAEDETDDDEAKVEEEAPEEKTPKTKKQTKTVWDWELMNDSKPIWTRKPADVTQDEYDAF
YKSLTKDTSEPLTQTHFVAEGEVTFKSLLFVPKIQPSESFNKYGSKSDNIKLYVRRVFIT
DEFNDLMPNYLGFIRGVVDSDDLPLNVSRETLQQHKLIKVIKKKLVRKALDMLKKLEGEE
YDKFWKEYSTNIKLGVMEDSSNRARLAKLLKFQSSNTKSGKLTSLSDYSSRMKPKQEWIY
YIAAASRAEAEKSPFIERLVARGYEVLFLVEAVDEYCISALPEFDGKKFQNVAKEGFSLP
ESEEAKEKFEELKNKFEPLAKWFADVGLKDKITKAMVSEKLTNTPCVLVASMFGWTGNME
RLAMSNAHKKAEDVSQSYYFNQKKALEFNPRHPVIKDLLRKIDADPQDPSAKEMAELLLD
TAVLRSGFMLTETRKFADSIDKLMRQAMNLQDAEFDPEIEEFPEPSNTDEPQTDADEEEI
DGDLEEHDEL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 28 | g3606.t1 | CDD | cd16927 | HATPase_Hsp90-like | 84 | 275 | 5.99273E-101 |
| 19 | g3606.t1 | Gene3D | G3DSA:3.30.565.10 | - | 75 | 283 | 4.9E-109 |
| 21 | g3606.t1 | Gene3D | G3DSA:3.30.70.2140 | - | 284 | 332 | 4.9E-109 |
| 20 | g3606.t1 | Gene3D | G3DSA:3.30.230.80 | - | 339 | 506 | 1.6E-71 |
| 17 | g3606.t1 | Gene3D | G3DSA:3.40.50.11260 | - | 507 | 594 | 5.2E-34 |
| 18 | g3606.t1 | Gene3D | G3DSA:1.20.120.790 | - | 595 | 748 | 6.9E-48 |
| 5 | g3606.t1 | Hamap | MF_00505 | Chaperone protein HtpG [htpG]. | 63 | 745 | 25.250807 |
| 33 | g3606.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 296 | 315 | - |
| 34 | g3606.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 296 | 328 | - |
| 31 | g3606.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 751 | 790 | - |
| 32 | g3606.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 754 | 790 | - |
| 3 | g3606.t1 | PANTHER | PTHR11528:SF96 | ENDOPLASMIN | 42 | 783 | 0.0 |
| 4 | g3606.t1 | PANTHER | PTHR11528 | HEAT SHOCK PROTEIN 90 FAMILY MEMBER | 42 | 783 | 0.0 |
| 27 | g3606.t1 | PIRSF | PIRSF002583 | HSP90_HTPG | 40 | 788 | 1.1E-243 |
| 12 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 75 | 95 | 7.7E-69 |
| 7 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 96 | 118 | 7.7E-69 |
| 8 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 145 | 162 | 7.7E-69 |
| 11 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 163 | 180 | 7.7E-69 |
| 10 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 192 | 214 | 7.7E-69 |
| 9 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 243 | 260 | 7.7E-69 |
| 6 | g3606.t1 | PRINTS | PR00775 | 90kDa heat shock protein signature | 261 | 279 | 7.7E-69 |
| 2 | g3606.t1 | Pfam | PF02518 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | 97 | 254 | 2.2E-11 |
| 1 | g3606.t1 | Pfam | PF00183 | Hsp90 protein | 257 | 770 | 5.6E-216 |
| 23 | g3606.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 23 | - |
| 24 | g3606.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 25 | g3606.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 15 | - |
| 26 | g3606.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 23 | - |
| 22 | g3606.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 24 | 790 | - |
| 30 | g3606.t1 | ProSitePatterns | PS00298 | Heat shock hsp90 proteins family signature. | 95 | 104 | - |
| 29 | g3606.t1 | SMART | SM00387 | HKATPase_4 | 97 | 255 | 6.5E-4 |
| 14 | g3606.t1 | SUPERFAMILY | SSF55874 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 75 | 285 | 1.05E-66 |
| 13 | g3606.t1 | SUPERFAMILY | SSF54211 | Ribosomal protein S5 domain 2-like | 341 | 595 | 6.98E-90 |
| 15 | g3606.t1 | SUPERFAMILY | SSF110942 | HSP90 C-terminal domain | 619 | 745 | 1.44E-23 |
| 16 | g3606.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 23 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006457 | protein folding | BP |
| GO:0005524 | ATP binding | MF |
| GO:0051082 | unfolded protein binding | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K09487 (heat shock protein 90kDa beta)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
