General information for g3639.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Venom carboxylesterase-6.
Parent gene
- The parent gene g3639 is located on chr_3: 27041669..27043795 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3639 | g3639.t1 | TTS | g3639.t1 | 27041515 | 27041515 |
| chr_3 | g3639 | g3639.t1 | isoform | g3639.t1 | 27041669 | 27043795 |
| chr_3 | g3639 | g3639.t1 | exon | g3639.t1.exon1 | 27041669 | 27041989 |
| chr_3 | g3639 | g3639.t1 | cds | g3639.t1.CDS1 | 27041669 | 27041989 |
| chr_3 | g3639 | g3639.t1 | exon | g3639.t1.exon2 | 27042054 | 27042158 |
| chr_3 | g3639 | g3639.t1 | cds | g3639.t1.CDS2 | 27042054 | 27042158 |
| chr_3 | g3639 | g3639.t1 | exon | g3639.t1.exon3 | 27042515 | 27043359 |
| chr_3 | g3639 | g3639.t1 | cds | g3639.t1.CDS3 | 27042515 | 27043359 |
| chr_3 | g3639 | g3639.t1 | exon | g3639.t1.exon4 | 27043414 | 27043795 |
| chr_3 | g3639 | g3639.t1 | cds | g3639.t1.CDS4 | 27043414 | 27043795 |
| chr_3 | g3639 | g3639.t1 | TSS | g3639.t1 | 27043979 | 27043979 |
Sequences
>g3639.t1 Gene=g3639 Length=1653
ATGGTTTTCCTTGAAGCAAAGTTTACAATTCTCATATTTTGTTCTGTGATGATGTTTACA
AATTTTCATCCAACACTGTATCTTGATTTACCAATTGTCCGAATTGAGAATGGTGAAATT
TTAGGTGAAGAACATGAAACATATTTTGCATTCAAGGGAATTCCTTATGCTGAAGCAGAA
AGATTTGCTCCACCAAGAAGAATTTTAAAGCGATGGTATCAAATTAGAAAGTTTGATAAA
TTTGGAGAACAGTGTGCACAATATAATCATATGGAATATAATTTTCTTGGAAGTGAAAAT
TGTCTCAGTTTGAATGTTTTTGTTCCGAAAAGTGTTTTGAAATCACGAGATTCAGTTCCT
GTAATAGTTTTCATTCATGGAGGTGCCTTTATGTTTGGAAGCAGCATATTTTATGGAGCT
GATATTATTATGCAAGAGCAAAATATTATTTTAGTTACTATTAATTACCGTCTAGGAGTT
TTAGGATTCTTGAGCACAGAAGATGAAATTATTCCGGGTAATTTAGGATTGAAAGATCAA
GTAGAAGCATTAAGATGGGTACAACGAAATATCAAAGCATTCAATGGTAATTCCAATAAA
GTAACTATCACAGGATTCTCTGCTGGCGGTGCAAGTGCTCAACTTCATATTTTAAGTTCA
CTTTCAAATGGTCTTTTTAACAATGCAATTTCTCATTCTGGATTTGCTTTAAATCCTTGG
GTTGTGATGGAAAATGCAAAAGCAAAAGCTTATCAAGTTGGAAATTATTTAAATTGTAAT
TTTCACAAAAACCATAAGCCCAATCACAAAATGTTATTGCAATGTCTTAAAAAAGTACCG
ACAGAAAAACTTGTAATGGCAGCAAAAATATTTCAACCATTTTTATATAATCCATTTTCA
CCATTTGGAGTAGTGATTGAAAAATACAATAAACATCCATTCCTTACCGCTCATCCAAAG
GTAATTTTAGAAAATCAAAAGTATCAAAAACGACCTTATATCGCTTCAATAACAAAAGAT
GAAGGTCTTTATCCAGCTGCTGAATTTTACAATAATGAAACAATCAAAGAAATTGATGAA
AATTGGGAAAGATTGGCTCCTTTTTTGCTTGACTTTAATTCTACGTCTAATAATAATGAA
TTAAAATTGGAATGGTCTAGAAAAATTAGAAAATTTTATTTTGACGATGAGAAAATCACG
ATTAATAATTTCCATAAACTTATTAAGCTTATAACAGATCGACTTTATAAAAACGGCTTC
TATAACTCTTTGGTTCTTCAATCATCTCATTCATCAAATTTATACTGCTATCATTTTACA
TATAATGTTACAAAATCATTCACTGATGATTTAAAAGAGTCCAAAAATTATCTTGGCATA
GCTCATGGAGATGATATATTTTTAATCTATAATAATCGTCGATTGAATGAATATTCAAAT
GATGAACTGATTATTGCTCATGACTTTGTGGAAATGTACAGAACTTTCTCACAAACAAAT
AATGCAGTTTATGCCAATCAGTCAATTAAACCGATTAAATCAAGTTCATTTGAATGTATT
AATATTGCTGCCGTTGCTAACAACAGAATGATTAAAATTGAAAACACATTCGGTGAGGTA
GATTTTTGGAAAACACTCAATATACCTGAATGA
>g3639.t1 Gene=g3639 Length=550
MVFLEAKFTILIFCSVMMFTNFHPTLYLDLPIVRIENGEILGEEHETYFAFKGIPYAEAE
RFAPPRRILKRWYQIRKFDKFGEQCAQYNHMEYNFLGSENCLSLNVFVPKSVLKSRDSVP
VIVFIHGGAFMFGSSIFYGADIIMQEQNIILVTINYRLGVLGFLSTEDEIIPGNLGLKDQ
VEALRWVQRNIKAFNGNSNKVTITGFSAGGASAQLHILSSLSNGLFNNAISHSGFALNPW
VVMENAKAKAYQVGNYLNCNFHKNHKPNHKMLLQCLKKVPTEKLVMAAKIFQPFLYNPFS
PFGVVIEKYNKHPFLTAHPKVILENQKYQKRPYIASITKDEGLYPAAEFYNNETIKEIDE
NWERLAPFLLDFNSTSNNNELKLEWSRKIRKFYFDDEKITINNFHKLIKLITDRLYKNGF
YNSLVLQSSHSSNLYCYHFTYNVTKSFTDDLKESKNYLGIAHGDDIFLIYNNRRLNEYSN
DELIIAHDFVEMYRTFSQTNNAVYANQSIKPIKSSSFECINIAAVANNRMIKIENTFGEV
DFWKTLNIPE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g3639.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 28 | 547 | 4.2E-130 |
| 2 | g3639.t1 | PANTHER | PTHR43142:SF1 | CARBOXYLIC ESTER HYDROLASE | 30 | 545 | 2.0E-110 |
| 3 | g3639.t1 | PANTHER | PTHR43142 | CARBOXYLIC ESTER HYDROLASE | 30 | 545 | 2.0E-110 |
| 1 | g3639.t1 | Pfam | PF00135 | Carboxylesterase family | 31 | 508 | 1.0E-113 |
| 8 | g3639.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 9 | g3639.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 28 | - |
| 6 | g3639.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 29 | 118 | - |
| 10 | g3639.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 119 | 140 | - |
| 7 | g3639.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 141 | 550 | - |
| 4 | g3639.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 29 | 503 | 9.88E-104 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K01044 (carboxylesterase 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed