General information for g3686.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Abnormal cell migration protein 10.
Parent gene
- The parent gene g3686 is located on chr_3: 27416283..27422327 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3686 | g3686.t1 | TTS | g3686.t1 | 27409204 | 27409204 |
| chr_3 | g3686 | g3686.t1 | isoform | g3686.t1 | 27410034 | 27422327 |
| chr_3 | g3686 | g3686.t1 | exon | g3686.t1.exon1 | 27410034 | 27412008 |
| chr_3 | g3686 | g3686.t1 | cds | g3686.t1.CDS1 | 27410034 | 27412008 |
| chr_3 | g3686 | g3686.t1 | exon | g3686.t1.exon2 | 27412081 | 27412324 |
| chr_3 | g3686 | g3686.t1 | cds | g3686.t1.CDS2 | 27412081 | 27412324 |
| chr_3 | g3686 | g3686.t1 | exon | g3686.t1.exon3 | 27412388 | 27412544 |
| chr_3 | g3686 | g3686.t1 | cds | g3686.t1.CDS3 | 27412388 | 27412544 |
| chr_3 | g3686 | g3686.t1 | exon | g3686.t1.exon4 | 27412606 | 27413034 |
| chr_3 | g3686 | g3686.t1 | cds | g3686.t1.CDS4 | 27412606 | 27413034 |
| chr_3 | g3686 | g3686.t1 | exon | g3686.t1.exon5 | 27422262 | 27422327 |
| chr_3 | g3686 | g3686.t1 | cds | g3686.t1.CDS5 | 27422262 | 27422327 |
| chr_3 | g3686 | g3686.t1 | TSS | g3686.t1 | NA | NA |
Sequences
>g3686.t1 Gene=g3686 Length=2871
ATGTCTACAGATGATCCGGAAAAATTATTGAATAATTGGCTTGGTGAACTAGACAGTTTA
ATTCTGGGATTAGAAATATACCATCAATCTCCTGTGAAATTAAGATCAAAGGAAACGCTC
TCAGTTCCAAAAGCAGAAAGAATAAATTCATATAGATTTTCAATGGCTAATTTAGAAGAA
ACACAAGAGTCAGAACTTGACTCTATTTTAACTGAACTAAGTCTTCTTGAGCAAAAAGGC
GAATTGAGACAGAGTAGACAACCAATACAAACACATAGTCGCTCAAGTTCGATTATTTCT
GGTGCGAATTCGACTATATCTACTGCCACAACTTCACATGATGTACGAGAATCATCACGT
ACCGAAAGTCCTGATAATGATTCTGCATTTAGCGATACAGTTTCATTGCTTTCAAGTGAA
TCATCAGCTTCAAGTGGTTTGAGTTCACTGAACAACATTAGTAAGATTCAAGTCTCACAG
AACAATCAAGTTCAAGATACAAAATCTTCAAAAATTCAACTTGCACTTCAAAAGCTTGAG
CATGCATCGATTAGAAGGCTCTTTGTAAAAGCATTTTCTGAAGATGGGTCCTCAAAATCA
TTATTAGTCGATGAACGAATGAATTGCGGTTTCGTAACGAAATTGTTAGCAGATAAAAAT
CATGTCAATATGGAAGTTAATTGGGGATTGATTGAATATTTACCAGAGCTTTATATTGAA
CGATTATTTGAAGATCACGAACAATTAGTAGAAAATTTATTACTATGGAGTAATGATAGT
AAAAATCGCGTCTTGTTTTTAAAACGAACCGACAGAGTGTCCTTATTTACCTCACCGGAA
CTTTACCTACCGTCGTTTGAGATGACACCAGGAACTCAGCATGATGAAGAATCAAGAAAT
CTTCTATTAGAAGAATTTTTTGCCAATAACAATCAAATATCATTAGAAGGTCCACTTTAT
CTAAAAAGTGAATCTAAGAAAGGCTGGAAAAAATATCATTTTGTTTTAAGGCCATCAGGT
CTATATTATTATCCAAAGGAAAAGGAAAAGACAAAATCATCGAAAGATTTGATGTGTTTA
GCACTTTTTAATGCTCATAATATCTATAAGGGCATAAGCTGGAAAAAGAAATATAAGTCA
CCCACTGATTTTGGTTTTGCACTAAAATGTCCTAAAGTGAATATAACAGGAAAAGGAATG
AAGATGTTATGTGCAGAGGACTCAGAAACACTTGAAAAGTGGATAATGTGTTGTCGTATA
GCAAAATATGGACGTAAATTGTTTGACAATTATAAAAATCTCATTGATGATTTAGCGCGT
GAAGATCTAGATAAAATTGCCTCCACAAGATTATCATTTACTCCAATTACGACACCAACA
AGCGCAGAAAAATTGAGTATCAATACCCCAAGCGGCCGTTGTTCACGAGCAAGTACGAGT
TCAAGTTCTAGTGGATGTCTTTCAGATGATAACAATGCATTTGAATCAGAATTTACAACG
GGAACAATCAAACGCAAACCCACAATTAAACCAAATCTTCCTTTAACATCAAAAACGCGT
CAGTTGATAAAAGAAGTTGAAGACAATACAGCCATTCGTGATGATAATGCAAGTGATCAA
AATGGTACACTTACACGTCGAAGGACGCATAGCAGTAGTAGTAATGGGACACTAAAGAGG
CAAAATTCAAATCGTTGTTCATTTGAGAGTATGAAATCTATAAACTCACCATTAACTCCA
GAAGACAGCATTAGTACGACAAGCAGTAATTATGGAGCTAATATTTTGATGAAAACGAGT
GATTCTTTAGATTCAGGCAAGTTGATGCAATCTTGTATGACAGATTCATTGCTTTCGCTT
CCACCACCACCTGAAGACTCATCTGCTGGTTGTATTATGTCCGCTTCAACTCTTTCACTT
AACTTACCCGAGCCACCAGATGAAGATACATTAAAACAAATGGCACGAAATGATTTTCTT
GATAATATTGCATCAAATTCTACTGAAGAATCTCAGATTTTAGAAACTAATACAATAAAT
AATAGCAATCCATTGCCACAACAAATTTTTAATGTAATATCTTCACCAATTCATAATAAT
CACGTTATTAATCAACATCAGCATCAAATGCCAGAAGTTGAACCAATTTATAAGACTATT
CTTAAACCACCACCCTACAAGTCACCGCCTCCTGTGCATAATCCAAGTATTAACATTAAA
TACAAATCTTCACCACCGCCTGTTCCTCAAAAAACTGTTACATTTGCTGACTCAACTTCA
TCGCCTATTATTCTCAGAAAGAAAGTGTGTTTCGATGACCAAGTAGAACAGATTCAGTTA
TTATCACGTAATGATAGACCACCACTTCCAATTCGTGATAGAAGTACTCAATTGACATCA
CCAAAACGTCTTTGCGATTCTTTATGTAACCCACCACAAGACTTTTGGAATGATTTACAA
CGTGTAGTTAATAAAAAATTAAGTGTTGCTCAAAAATGTAAAATGAATGCGCAAATGACA
CCCGGAGAAGTACTTGGCTTCCGTGATGTAGAACAGATTTATGATACAAATGTAAACTAT
AGAGAAACGTCCACTACAAACTGGGTAATTGAACATTATGGTGATAATTTATATGAAAAT
TGGAATGGAAAACATAATAACAATAAAAGCAATAGTATCAATGAAAGTTCTATTGGAACC
CTTCAAAATTCCCAAGTTATATATCGTGACATCAACAAACAAAATTCGAATCTTCCTCTA
AGTCCACAACGTCGATCGACACGTGGACCACCAGTACCGATTCGAAATTCTACTACACGA
TTAAGTACATCTAATGGAAGTTCGAATAATAATCTTAATGAAATGCAATAA
>g3686.t1 Gene=g3686 Length=956
MSTDDPEKLLNNWLGELDSLILGLEIYHQSPVKLRSKETLSVPKAERINSYRFSMANLEE
TQESELDSILTELSLLEQKGELRQSRQPIQTHSRSSSIISGANSTISTATTSHDVRESSR
TESPDNDSAFSDTVSLLSSESSASSGLSSLNNISKIQVSQNNQVQDTKSSKIQLALQKLE
HASIRRLFVKAFSEDGSSKSLLVDERMNCGFVTKLLADKNHVNMEVNWGLIEYLPELYIE
RLFEDHEQLVENLLLWSNDSKNRVLFLKRTDRVSLFTSPELYLPSFEMTPGTQHDEESRN
LLLEEFFANNNQISLEGPLYLKSESKKGWKKYHFVLRPSGLYYYPKEKEKTKSSKDLMCL
ALFNAHNIYKGISWKKKYKSPTDFGFALKCPKVNITGKGMKMLCAEDSETLEKWIMCCRI
AKYGRKLFDNYKNLIDDLAREDLDKIASTRLSFTPITTPTSAEKLSINTPSGRCSRASTS
SSSSGCLSDDNNAFESEFTTGTIKRKPTIKPNLPLTSKTRQLIKEVEDNTAIRDDNASDQ
NGTLTRRRTHSSSSNGTLKRQNSNRCSFESMKSINSPLTPEDSISTTSSNYGANILMKTS
DSLDSGKLMQSCMTDSLLSLPPPPEDSSAGCIMSASTLSLNLPEPPDEDTLKQMARNDFL
DNIASNSTEESQILETNTINNSNPLPQQIFNVISSPIHNNHVINQHQHQMPEVEPIYKTI
LKPPPYKSPPPVHNPSINIKYKSSPPPVPQKTVTFADSTSSPIILRKKVCFDDQVEQIQL
LSRNDRPPLPIRDRSTQLTSPKRLCDSLCNPPQDFWNDLQRVVNKKLSVAQKCKMNAQMT
PGEVLGFRDVEQIYDTNVNYRETSTTNWVIEHYGDNLYENWNGKHNNNKSNSINESSIGT
LQNSQVIYRDINKQNSNLPLSPQRRSTRGPPVPIRNSTTRLSTSNGSSNNNLNEMQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g3686.t1 | CDD | cd01259 | PH_APBB1IP | 309 | 432 | 7.67291E-46 |
| 9 | g3686.t1 | Coils | Coil | Coil | 59 | 79 | - |
| 7 | g3686.t1 | Gene3D | G3DSA:3.10.20.90 | - | 156 | 272 | 1.0E-34 |
| 8 | g3686.t1 | Gene3D | G3DSA:2.30.29.30 | - | 274 | 437 | 1.5E-51 |
| 15 | g3686.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 81 | 133 | - |
| 17 | g3686.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 81 | 114 | - |
| 14 | g3686.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 526 | 585 | - |
| 13 | g3686.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 535 | 585 | - |
| 16 | g3686.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 914 | 956 | - |
| 3 | g3686.t1 | PANTHER | PTHR11243:SF23 | LD06925P | 7 | 848 | 1.3E-183 |
| 4 | g3686.t1 | PANTHER | PTHR11243 | GROWTH FACTOR RECEPTOR-BOUND PROTEIN | 7 | 848 | 1.3E-183 |
| 2 | g3686.t1 | Pfam | PF00788 | Ras association (RalGDS/AF-6) domain | 187 | 271 | 1.8E-9 |
| 1 | g3686.t1 | Pfam | PF00169 | PH domain | 315 | 421 | 7.4E-8 |
| 18 | g3686.t1 | ProSiteProfiles | PS50200 | Ras-associating (RA) domain profile. | 181 | 272 | 20.685 |
| 19 | g3686.t1 | ProSiteProfiles | PS50003 | PH domain profile. | 312 | 423 | 9.942 |
| 12 | g3686.t1 | SMART | SM00314 | RA_5 | 183 | 272 | 8.9E-10 |
| 11 | g3686.t1 | SMART | SM00233 | PH_update | 313 | 425 | 7.7E-11 |
| 6 | g3686.t1 | SUPERFAMILY | SSF54236 | Ubiquitin-like | 180 | 273 | 2.27E-23 |
| 5 | g3686.t1 | SUPERFAMILY | SSF50729 | PH domain-like | 311 | 420 | 3.29E-16 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
KEGG
Orthology
- This transcript has been annotated with K23488 (Ras-associated and pleckstrin homology domains-containing protein 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
