General information for g3686.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Abnormal cell migration protein 10.
Parent gene
- The parent gene g3686 is located on chr_3: 27416283..27422327 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3686 | g3686.t2 | TTS | g3686.t2 | 27409204 | 27409204 |
| chr_3 | g3686 | g3686.t2 | isoform | g3686.t2 | 27410034 | 27416283 |
| chr_3 | g3686 | g3686.t2 | exon | g3686.t2.exon1 | 27410034 | 27412008 |
| chr_3 | g3686 | g3686.t2 | cds | g3686.t2.CDS1 | 27410034 | 27412008 |
| chr_3 | g3686 | g3686.t2 | exon | g3686.t2.exon2 | 27412081 | 27412324 |
| chr_3 | g3686 | g3686.t2 | cds | g3686.t2.CDS2 | 27412081 | 27412324 |
| chr_3 | g3686 | g3686.t2 | exon | g3686.t2.exon3 | 27412388 | 27412544 |
| chr_3 | g3686 | g3686.t2 | cds | g3686.t2.CDS3 | 27412388 | 27412544 |
| chr_3 | g3686 | g3686.t2 | exon | g3686.t2.exon4 | 27412606 | 27413034 |
| chr_3 | g3686 | g3686.t2 | cds | g3686.t2.CDS4 | 27412606 | 27413034 |
| chr_3 | g3686 | g3686.t2 | exon | g3686.t2.exon5 | 27416224 | 27416283 |
| chr_3 | g3686 | g3686.t2 | cds | g3686.t2.CDS5 | 27416224 | 27416283 |
| chr_3 | g3686 | g3686.t2 | TSS | g3686.t2 | 27416832 | 27416832 |
Sequences
>g3686.t2 Gene=g3686 Length=2865
ATGGATTATAATTCAAATCGATGGTCTGATTTTGATTCAATCTCGACATATTCAAGTGAA
GGATTAGAAATATACCATCAATCTCCTGTGAAATTAAGATCAAAGGAAACGCTCTCAGTT
CCAAAAGCAGAAAGAATAAATTCATATAGATTTTCAATGGCTAATTTAGAAGAAACACAA
GAGTCAGAACTTGACTCTATTTTAACTGAACTAAGTCTTCTTGAGCAAAAAGGCGAATTG
AGACAGAGTAGACAACCAATACAAACACATAGTCGCTCAAGTTCGATTATTTCTGGTGCG
AATTCGACTATATCTACTGCCACAACTTCACATGATGTACGAGAATCATCACGTACCGAA
AGTCCTGATAATGATTCTGCATTTAGCGATACAGTTTCATTGCTTTCAAGTGAATCATCA
GCTTCAAGTGGTTTGAGTTCACTGAACAACATTAGTAAGATTCAAGTCTCACAGAACAAT
CAAGTTCAAGATACAAAATCTTCAAAAATTCAACTTGCACTTCAAAAGCTTGAGCATGCA
TCGATTAGAAGGCTCTTTGTAAAAGCATTTTCTGAAGATGGGTCCTCAAAATCATTATTA
GTCGATGAACGAATGAATTGCGGTTTCGTAACGAAATTGTTAGCAGATAAAAATCATGTC
AATATGGAAGTTAATTGGGGATTGATTGAATATTTACCAGAGCTTTATATTGAACGATTA
TTTGAAGATCACGAACAATTAGTAGAAAATTTATTACTATGGAGTAATGATAGTAAAAAT
CGCGTCTTGTTTTTAAAACGAACCGACAGAGTGTCCTTATTTACCTCACCGGAACTTTAC
CTACCGTCGTTTGAGATGACACCAGGAACTCAGCATGATGAAGAATCAAGAAATCTTCTA
TTAGAAGAATTTTTTGCCAATAACAATCAAATATCATTAGAAGGTCCACTTTATCTAAAA
AGTGAATCTAAGAAAGGCTGGAAAAAATATCATTTTGTTTTAAGGCCATCAGGTCTATAT
TATTATCCAAAGGAAAAGGAAAAGACAAAATCATCGAAAGATTTGATGTGTTTAGCACTT
TTTAATGCTCATAATATCTATAAGGGCATAAGCTGGAAAAAGAAATATAAGTCACCCACT
GATTTTGGTTTTGCACTAAAATGTCCTAAAGTGAATATAACAGGAAAAGGAATGAAGATG
TTATGTGCAGAGGACTCAGAAACACTTGAAAAGTGGATAATGTGTTGTCGTATAGCAAAA
TATGGACGTAAATTGTTTGACAATTATAAAAATCTCATTGATGATTTAGCGCGTGAAGAT
CTAGATAAAATTGCCTCCACAAGATTATCATTTACTCCAATTACGACACCAACAAGCGCA
GAAAAATTGAGTATCAATACCCCAAGCGGCCGTTGTTCACGAGCAAGTACGAGTTCAAGT
TCTAGTGGATGTCTTTCAGATGATAACAATGCATTTGAATCAGAATTTACAACGGGAACA
ATCAAACGCAAACCCACAATTAAACCAAATCTTCCTTTAACATCAAAAACGCGTCAGTTG
ATAAAAGAAGTTGAAGACAATACAGCCATTCGTGATGATAATGCAAGTGATCAAAATGGT
ACACTTACACGTCGAAGGACGCATAGCAGTAGTAGTAATGGGACACTAAAGAGGCAAAAT
TCAAATCGTTGTTCATTTGAGAGTATGAAATCTATAAACTCACCATTAACTCCAGAAGAC
AGCATTAGTACGACAAGCAGTAATTATGGAGCTAATATTTTGATGAAAACGAGTGATTCT
TTAGATTCAGGCAAGTTGATGCAATCTTGTATGACAGATTCATTGCTTTCGCTTCCACCA
CCACCTGAAGACTCATCTGCTGGTTGTATTATGTCCGCTTCAACTCTTTCACTTAACTTA
CCCGAGCCACCAGATGAAGATACATTAAAACAAATGGCACGAAATGATTTTCTTGATAAT
ATTGCATCAAATTCTACTGAAGAATCTCAGATTTTAGAAACTAATACAATAAATAATAGC
AATCCATTGCCACAACAAATTTTTAATGTAATATCTTCACCAATTCATAATAATCACGTT
ATTAATCAACATCAGCATCAAATGCCAGAAGTTGAACCAATTTATAAGACTATTCTTAAA
CCACCACCCTACAAGTCACCGCCTCCTGTGCATAATCCAAGTATTAACATTAAATACAAA
TCTTCACCACCGCCTGTTCCTCAAAAAACTGTTACATTTGCTGACTCAACTTCATCGCCT
ATTATTCTCAGAAAGAAAGTGTGTTTCGATGACCAAGTAGAACAGATTCAGTTATTATCA
CGTAATGATAGACCACCACTTCCAATTCGTGATAGAAGTACTCAATTGACATCACCAAAA
CGTCTTTGCGATTCTTTATGTAACCCACCACAAGACTTTTGGAATGATTTACAACGTGTA
GTTAATAAAAAATTAAGTGTTGCTCAAAAATGTAAAATGAATGCGCAAATGACACCCGGA
GAAGTACTTGGCTTCCGTGATGTAGAACAGATTTATGATACAAATGTAAACTATAGAGAA
ACGTCCACTACAAACTGGGTAATTGAACATTATGGTGATAATTTATATGAAAATTGGAAT
GGAAAACATAATAACAATAAAAGCAATAGTATCAATGAAAGTTCTATTGGAACCCTTCAA
AATTCCCAAGTTATATATCGTGACATCAACAAACAAAATTCGAATCTTCCTCTAAGTCCA
CAACGTCGATCGACACGTGGACCACCAGTACCGATTCGAAATTCTACTACACGATTAAGT
ACATCTAATGGAAGTTCGAATAATAATCTTAATGAAATGCAATAA
>g3686.t2 Gene=g3686 Length=954
MDYNSNRWSDFDSISTYSSEGLEIYHQSPVKLRSKETLSVPKAERINSYRFSMANLEETQ
ESELDSILTELSLLEQKGELRQSRQPIQTHSRSSSIISGANSTISTATTSHDVRESSRTE
SPDNDSAFSDTVSLLSSESSASSGLSSLNNISKIQVSQNNQVQDTKSSKIQLALQKLEHA
SIRRLFVKAFSEDGSSKSLLVDERMNCGFVTKLLADKNHVNMEVNWGLIEYLPELYIERL
FEDHEQLVENLLLWSNDSKNRVLFLKRTDRVSLFTSPELYLPSFEMTPGTQHDEESRNLL
LEEFFANNNQISLEGPLYLKSESKKGWKKYHFVLRPSGLYYYPKEKEKTKSSKDLMCLAL
FNAHNIYKGISWKKKYKSPTDFGFALKCPKVNITGKGMKMLCAEDSETLEKWIMCCRIAK
YGRKLFDNYKNLIDDLAREDLDKIASTRLSFTPITTPTSAEKLSINTPSGRCSRASTSSS
SSGCLSDDNNAFESEFTTGTIKRKPTIKPNLPLTSKTRQLIKEVEDNTAIRDDNASDQNG
TLTRRRTHSSSSNGTLKRQNSNRCSFESMKSINSPLTPEDSISTTSSNYGANILMKTSDS
LDSGKLMQSCMTDSLLSLPPPPEDSSAGCIMSASTLSLNLPEPPDEDTLKQMARNDFLDN
IASNSTEESQILETNTINNSNPLPQQIFNVISSPIHNNHVINQHQHQMPEVEPIYKTILK
PPPYKSPPPVHNPSINIKYKSSPPPVPQKTVTFADSTSSPIILRKKVCFDDQVEQIQLLS
RNDRPPLPIRDRSTQLTSPKRLCDSLCNPPQDFWNDLQRVVNKKLSVAQKCKMNAQMTPG
EVLGFRDVEQIYDTNVNYRETSTTNWVIEHYGDNLYENWNGKHNNNKSNSINESSIGTLQ
NSQVIYRDINKQNSNLPLSPQRRSTRGPPVPIRNSTTRLSTSNGSSNNNLNEMQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g3686.t2 | CDD | cd01259 | PH_APBB1IP | 307 | 430 | 9.65962E-46 |
| 10 | g3686.t2 | Coils | Coil | Coil | 57 | 77 | - |
| 9 | g3686.t2 | Coils | Coil | Coil | 947 | 954 | - |
| 7 | g3686.t2 | Gene3D | G3DSA:3.10.20.90 | - | 154 | 270 | 1.0E-34 |
| 8 | g3686.t2 | Gene3D | G3DSA:2.30.29.30 | - | 272 | 435 | 1.5E-51 |
| 16 | g3686.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 79 | 131 | - |
| 17 | g3686.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 79 | 112 | - |
| 18 | g3686.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 524 | 583 | - |
| 15 | g3686.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 533 | 583 | - |
| 14 | g3686.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 912 | 954 | - |
| 3 | g3686.t2 | PANTHER | PTHR11243:SF23 | LD06925P | 32 | 846 | 5.5E-181 |
| 4 | g3686.t2 | PANTHER | PTHR11243 | GROWTH FACTOR RECEPTOR-BOUND PROTEIN | 32 | 846 | 5.5E-181 |
| 2 | g3686.t2 | Pfam | PF00788 | Ras association (RalGDS/AF-6) domain | 185 | 269 | 1.7E-9 |
| 1 | g3686.t2 | Pfam | PF00169 | PH domain | 313 | 419 | 7.4E-8 |
| 19 | g3686.t2 | ProSiteProfiles | PS50200 | Ras-associating (RA) domain profile. | 179 | 270 | 20.685 |
| 20 | g3686.t2 | ProSiteProfiles | PS50003 | PH domain profile. | 310 | 421 | 9.942 |
| 13 | g3686.t2 | SMART | SM00314 | RA_5 | 181 | 270 | 8.9E-10 |
| 12 | g3686.t2 | SMART | SM00233 | PH_update | 311 | 423 | 7.7E-11 |
| 6 | g3686.t2 | SUPERFAMILY | SSF54236 | Ubiquitin-like | 178 | 271 | 2.27E-23 |
| 5 | g3686.t2 | SUPERFAMILY | SSF50729 | PH domain-like | 309 | 418 | 3.29E-16 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
KEGG
Orthology
- This transcript has been annotated with K23488 (Ras-associated and pleckstrin homology domains-containing protein 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
