General information for g3693.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome non-ATPase regulatory subunit 7.
Parent gene
- The parent gene g3693 is located on chr_3: 27483618..27491936 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3693 | g3693.t2 | isoform | g3693.t2 | 27478152 | 27484613 |
| chr_3 | g3693 | g3693.t2 | exon | g3693.t2.exon1 | 27478152 | 27478158 |
| chr_3 | g3693 | g3693.t2 | exon | g3693.t2.exon2 | 27483576 | 27484378 |
| chr_3 | g3693 | g3693.t2 | cds | g3693.t2.CDS1 | 27483684 | 27484378 |
| chr_3 | g3693 | g3693.t2 | exon | g3693.t2.exon3 | 27484442 | 27484613 |
| chr_3 | g3693 | g3693.t2 | cds | g3693.t2.CDS2 | 27484442 | 27484613 |
| chr_3 | g3693 | g3693.t2 | TSS | g3693.t2 | 27484712 | 27484712 |
| chr_3 | g3693 | g3693.t2 | TTS | g3693.t2 | NA | NA |
Sequences
>g3693.t2 Gene=g3693 Length=982
ATGCCTGCCGAACTTTCAACCGCAAAAGTAGTAATTCATCCATTGGTTTTGCTATCAGTT
GTCGATCATTTCACTAGAATGAGTAAAATTGGTAATCAAAAGAGAGTTGTTGGTGTTTTG
CTTGGTTGTTGGAAAGCAAAAGGAATTTTAGATGTTTCAAACAGTTTTGCAGTTCCATTT
GATGAAGATGATAAAGATAAAAGTGTTTGGTTCTTGGATCATGATTATCTTGAATCAATG
TATGGTATGTTCAAGAAAGTAAATGCACGTGAAAGAGTTGTTGGCTGGTATCATACGGGA
CCAAAATTACATCAGAATGATATTGCAATTAATGAACTTTTGCGACGCTATTGCCCAAAT
TCAGTGTTAGTTATAATAGATGCTCATCCGAAAGAACTTGGTTTGCCTACTGAAGCATAT
ATTGCAGTTGAAGAGGTTCATGATGATGGAACATTAACTAAAAAAACATTTGAGCATGTC
CCGAGTCAAATTGGTGCAGAAGAAGCTGAAGAAGTTGGTGTTGAACACCTATTACGTGAT
ATCAAAGACACTACTGTTGGAAGTTTGTCACAGAAAGTCACGAATCAACTATTGGGTTTA
AAAGGACTAAATGCGCAACTTCGAGATATTAAAGAGTATCTACTCAAAGTTGGAAATGGA
GAAATGCCCATCAATCATCAAATTATGTATCAAATGCAAGATATTTTCAATCTTCTTCCC
GACATTAGTCATGATAATTTCACCGACACTCTTTATATCAAGACTAACGATCAAATGCTT
GTTGTTTATTTAGCTTCATTGGTTCGATCCATTATTGCTTTACATAATTTAATTAACAAT
AAGCTTACAGAAGTATGTCAAGAATAAAAGGACATGTTTGATGTATGAATTCTCTTCTCT
ATTTGTATTTCTTGAATTCAATAAACACTTACAAACTGAACTTTATGAATTTAATAAACA
TTTATATTTAAACTTTAAAAAA
>g3693.t2 Gene=g3693 Length=288
MPAELSTAKVVIHPLVLLSVVDHFTRMSKIGNQKRVVGVLLGCWKAKGILDVSNSFAVPF
DEDDKDKSVWFLDHDYLESMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELLRRYCPN
SVLVIIDAHPKELGLPTEAYIAVEEVHDDGTLTKKTFEHVPSQIGAEEAEEVGVEHLLRD
IKDTTVGSLSQKVTNQLLGLKGLNAQLRDIKEYLLKVGNGEMPINHQIMYQMQDIFNLLP
DISHDNFTDTLYIKTNDQMLVVYLASLVRSIIALHNLINNKLTEVCQE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g3693.t2 | CDD | cd08062 | MPN_RPN7_8 | 9 | 282 | 0.000 |
| 6 | g3693.t2 | Gene3D | G3DSA:3.40.140.10 | Cytidine Deaminase | 3 | 187 | 0.000 |
| 3 | g3693.t2 | PANTHER | PTHR10540:SF12 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 | 3 | 283 | 0.000 |
| 4 | g3693.t2 | PANTHER | PTHR10540 | EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED | 3 | 283 | 0.000 |
| 2 | g3693.t2 | Pfam | PF01398 | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | 7 | 120 | 0.000 |
| 1 | g3693.t2 | Pfam | PF13012 | Maintenance of mitochondrial structure and function | 168 | 279 | 0.000 |
| 7 | g3693.t2 | ProSiteProfiles | PS50249 | MPN domain profile. | 10 | 146 | 19.323 |
| 5 | g3693.t2 | SMART | SM00232 | pad1_6 | 9 | 145 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008237 | metallopeptidase activity | MF |
| GO:0005515 | protein binding | MF |
| GO:0005838 | proteasome regulatory particle | CC |
| GO:0070122 | isopeptidase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03038 (26S proteasome regulatory subunit N8)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
