General information for g3707.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein phosphatase 5.
Parent gene
- The parent gene g3707 is located on chr_3: 27570043..27570764 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3707 | g3707.t3 | TSS | g3707.t3 | 27568731 | 27568731 |
| chr_3 | g3707 | g3707.t3 | isoform | g3707.t3 | 27568802 | 27570407 |
| chr_3 | g3707 | g3707.t3 | exon | g3707.t3.exon1 | 27568802 | 27568892 |
| chr_3 | g3707 | g3707.t3 | cds | g3707.t3.CDS1 | 27568802 | 27568892 |
| chr_3 | g3707 | g3707.t3 | exon | g3707.t3.exon2 | 27569257 | 27569874 |
| chr_3 | g3707 | g3707.t3 | cds | g3707.t3.CDS2 | 27569257 | 27569874 |
| chr_3 | g3707 | g3707.t3 | exon | g3707.t3.exon3 | 27569940 | 27570407 |
| chr_3 | g3707 | g3707.t3 | cds | g3707.t3.CDS3 | 27569940 | 27570406 |
| chr_3 | g3707 | g3707.t3 | TTS | g3707.t3 | 27570813 | 27570813 |
Sequences
>g3707.t3 Gene=g3707 Length=1177
ATGGCAACTGAAGTCAAAAATGGAAGTCCAACTGCAGAGCAGATAGCAGAGGCTGATAAA
TATAAAGAACAAGCTAATGAATACTTCAAAAATAAAATATATGATAAGGCTATCGAGTTA
TATTCAAAGGCAATTGAGTTAGACCCAAATAATGCAGTTTATTATGCAAACAGATCACTT
GCAAATCTTCGAACAGAATTATTTGGATATGCACTTAACGATGCTGTTAAGGCTGTAAAG
GCTGATCCAGGATACTTAAAAGGATATTATCGTCGAGCGGCAGCACATATGTCTTTAGGA
AAATTCAAACTCGCACTTGCTGACTTTGAGATTGTAAGTAAGAGAAGACCAAACGATTCC
GATGCTAAAAAGAAATTCGTAGAGTGCAATAAGATTGTAAAAAAGATTGCATTCGAGAGA
GCGATTGCTGTTGATAGACCAGAAAAAACTCTGGCTGAAATGTATCAAAGTTTAGACTCG
ATCTCAATTGAAGATGATTATAATGGACCAAAATTAAAAGACGACGAAACAGTTACCATA
GAATTTATGAAAGAGCTAATGCAATGGTACAAAGATCAAAAGAAATTACACAAGAAGTTT
GCTTATAAAATTCTTTACGACATTGATTCCTATCTAAGGAAACAGCCTTCACTCGTTGAT
ATTTCAATTCCTGATGAAGGAAAATTTACGATTTGTGGAGATATTCATGGGCAATTTTAT
GATCTATTAAACATTTTTGAAAAAAATGGTCTTCCTTCCGAAACAAATCCTTATTTATTC
AATGGTGATTTTGTTGATCGTGGTTCGTTTAGTGTTGAATGTATTTTTACACTATTTGGT
TTTAAACTGCTATATCCAAATCATTTTTATATGAGCCGAGGAAATCATGAATCAGTAAAT
ATGAATCAAATGTATGGCTTTACTGGTGAAGTAACAGCAAAATATAATAGCACTATGGCT
GATATGTTCACGCAAGTTTTTAATTTCTTGCCACTATCACATGTGCTCAATAATAAAGTG
CTTGTATGTCACGGTGGCCTCTTTTCAAGTGATGATGTTATGCTCGATGATTTACGTAAA
ATTGAAAGAAATAGGCAACCTCCAGAGGAAGGTTTAATGTGTGAATTACTATGGTCAGAT
CCACAAGCTCAAAATGGTAGAGCTCCTTCAAAACGAG
>g3707.t3 Gene=g3707 Length=392
MATEVKNGSPTAEQIAEADKYKEQANEYFKNKIYDKAIELYSKAIELDPNNAVYYANRSL
ANLRTELFGYALNDAVKAVKADPGYLKGYYRRAAAHMSLGKFKLALADFEIVSKRRPNDS
DAKKKFVECNKIVKKIAFERAIAVDRPEKTLAEMYQSLDSISIEDDYNGPKLKDDETVTI
EFMKELMQWYKDQKKLHKKFAYKILYDIDSYLRKQPSLVDISIPDEGKFTICGDIHGQFY
DLLNIFEKNGLPSETNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFYMSRGNHESVN
MNQMYGFTGEVTAKYNSTMADMFTQVFNFLPLSHVLNNKVLVCHGGLFSSDDVMLDDLRK
IERNRQPPEEGLMCELLWSDPQAQNGRAPSKR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g3707.t3 | Gene3D | G3DSA:1.25.40.10 | - | 7 | 169 | 0.0000e+00 |
| 14 | g3707.t3 | Gene3D | G3DSA:3.60.21.10 | - | 170 | 392 | 0.0000e+00 |
| 4 | g3707.t3 | PANTHER | PTHR45668 | SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED | 21 | 392 | 0.0000e+00 |
| 5 | g3707.t3 | PANTHER | PTHR45668:SF5 | SERINE/THREONINE-PROTEIN PHOSPHATASE 5 | 21 | 392 | 0.0000e+00 |
| 15 | g3707.t3 | PIRSF | PIRSF033096 | PPPtase_5 | 5 | 392 | 0.0000e+00 |
| 8 | g3707.t3 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 228 | 255 | 0.0000e+00 |
| 6 | g3707.t3 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 258 | 285 | 0.0000e+00 |
| 7 | g3707.t3 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 291 | 315 | 0.0000e+00 |
| 10 | g3707.t3 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 325 | 351 | 0.0000e+00 |
| 9 | g3707.t3 | PRINTS | PR00114 | Serine/threonine phosphatase family signature | 355 | 382 | 0.0000e+00 |
| 2 | g3707.t3 | Pfam | PF00515 | Tetratricopeptide repeat | 19 | 51 | 0.0000e+00 |
| 1 | g3707.t3 | Pfam | PF08321 | PPP5 TPR repeat region | 128 | 220 | 0.0000e+00 |
| 3 | g3707.t3 | Pfam | PF00149 | Calcineurin-like phosphoesterase | 228 | 382 | 0.0000e+00 |
| 21 | g3707.t3 | ProSiteProfiles | PS50005 | TPR repeat profile. | 18 | 51 | 1.2567e+01 |
| 22 | g3707.t3 | ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 18 | 119 | 2.0680e+01 |
| 20 | g3707.t3 | ProSiteProfiles | PS50005 | TPR repeat profile. | 86 | 119 | 7.4340e+00 |
| 18 | g3707.t3 | SMART | SM00028 | tpr_5 | 18 | 51 | 3.0000e-07 |
| 17 | g3707.t3 | SMART | SM00028 | tpr_5 | 52 | 85 | 1.2000e+02 |
| 16 | g3707.t3 | SMART | SM00028 | tpr_5 | 86 | 119 | 1.4000e-03 |
| 19 | g3707.t3 | SMART | SM00156 | pp2a_7 | 196 | 392 | 0.0000e+00 |
| 11 | g3707.t3 | SUPERFAMILY | SSF48452 | TPR-like | 17 | 130 | 0.0000e+00 |
| 12 | g3707.t3 | SUPERFAMILY | SSF56300 | Metallo-dependent phosphatases | 177 | 392 | 0.0000e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0005515 | protein binding | MF |
| GO:0004721 | phosphoprotein phosphatase activity | MF |
| GO:0006470 | protein dephosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
