General information for g3722.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Beta-arrestin-1.
Parent gene
- The parent gene g3722 is located on chr_3: 27647989..27650034 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3722 | g3722.t3 | TTS | g3722.t3 | 27645223 | 27645223 |
| chr_3 | g3722 | g3722.t3 | isoform | g3722.t3 | 27645813 | 27650034 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon1 | 27645813 | 27645891 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS1 | 27645813 | 27645891 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon2 | 27645970 | 27646170 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS2 | 27645970 | 27646170 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon3 | 27646351 | 27646437 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS3 | 27646351 | 27646437 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon4 | 27647185 | 27647328 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS4 | 27647185 | 27647328 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon5 | 27647548 | 27647702 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS5 | 27647548 | 27647702 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon6 | 27647779 | 27647996 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS6 | 27647779 | 27647996 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon7 | 27648084 | 27648234 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS7 | 27648084 | 27648234 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon8 | 27648295 | 27648437 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS8 | 27648295 | 27648437 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon9 | 27648559 | 27648650 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS9 | 27648559 | 27648650 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon10 | 27648738 | 27649068 |
| chr_3 | g3722 | g3722.t3 | cds | g3722.t3.CDS10 | 27648738 | 27648814 |
| chr_3 | g3722 | g3722.t3 | exon | g3722.t3.exon11 | 27649792 | 27650034 |
| chr_3 | g3722 | g3722.t3 | TSS | g3722.t3 | 27650033 | 27650033 |
Sequences
>g3722.t3 Gene=g3722 Length=1844
AATTCATTCGCAAATTTTTCTTCTCTAAGTTTTGAAAAAAGTTTAATTTTTCGTGATTTT
GGTTTTATATTACAAAAAATAGTGTACTATTAAAGAAAATGTATAATATAAGTACCAGAA
GAGAATATAAACAAATTATTTTGTGACCAAGTATTGTGTTTCAAAGCCAAATTTATCGAG
TTCTTAGAAAAGAGAAAAATCATATTCAAAAGAATTAATCATTAATCTCCGAAAAAAACT
ATGATAAAATCAAGAGTATAAAAAGAAAAATAAAAAGTATCGAAGGATGTTCTGAAACAA
TCATCAAACACAAATATATACATATAGCTCATAATAAATTTTATAGCAAGCAACCGAGCT
AGAACGCATAATACATAGTTTATTTCTGCCTATAGAGTAACACATAATAAAATAAAACAT
TAGAGAAACAGAGTGAGTAACAAGTTGAAATAAATAGAGGAATGAAAAAATTAGATACAC
ATATAGTGTCATCCGCAATGCAAACAACGTCGTCTCATTCACCAAACCCTTCTCCTGAAA
TTGATGATGCTAGTTCGAAACGACAAGCCACACGTGTTTTCAAAAAATCTTCTGCAAATG
GAAAAATTACAGTATATCTGGGCAAGCGAGATTTTGTCGATCACATTACGCACGTCGATC
CAATCGACGGTGTTGTTCTCATCGATCCGGATTATATGAAAGATAGAAAAGTATTTGGTC
ACGTTTTGGCTGCATTTCGGTATGGTCGCGAGGATTTGGATGTCTTAGGATTAACATTTC
GCAAAGACCTTTACTTGGCATCAGAACAAATTTACCCCTGCTTACAAGATGTGAATGAAA
GAAGGCCATTAACACGCTTACAGGAACGTCTCATAAAGAAATTAGGACCAAATGCATATC
CATTCTATTTTGAATTGCCACCACATTGTCCAGCCAGCGTTTCACTTCAACCAGCGCCTG
GTGACACAGGAAAGCCTTGCGGCGTTGACTACGAACTAAAAGCATTCGTAGGTGACTGTA
GTGAGGATAAGCCTCATAAACGAAATTCCGTTAGATTGGCAATAAGAAAAATTATGTATG
CACCGTCGAAAGTCGGTGAACAACCATCAATTGAAGTTAGTAAAGAATTTATGTTAAAAC
CAAATAAAATTCATCTTGAAGCCAGTTTGGATAAAGAGCTTTACCATCATGGTGAAAATA
TATCAGTGAATGTACATATTGCAAATAACTCGAGTAAAACAGTAAAGAAAATTAAAGTTT
CGGTCAGACAGTTTGCGGATATATGTTTGTTTTCCACTGCACAATATAAGTGCAATGTTG
CCGAAGTCGAAGATGATGGATGCCAAGTACAGCCGGGATTTACTCTCTCAAAAGTATTTT
CGCTGACACCATTACTAGCGAACAACAAAGATAAGTGGGGACTAGCGTTAGATGGTCAAT
TGAAACATGAAGATACAAATCTTGCTTCGAGTACATTAATTGCGGATCCATCACAACGCG
AAAACTTGGGAATTATTGTGCAATATAAAGTAAAAGTAAAATTGTGTATCACACCACTCG
GAGGAGACCTTGTTGCTGAACTACCTTTTATTTTAATGCATCCAAAACCTGACGATTTAG
ATGAGAATAATTTGATAATAGACCAAAGTACATCAAATAATGAGAATAAAGTAAACATAC
AAAGCAAGGACTCTTCTGAGAAAGGAATAATCAGTTCACCACAGACAGTTAAAGATGATG
TGCCAAATTTAATTCAACTTGATGGCGACGATACACATGATGATGATATAATTTTTGAGG
ACTTTGCTCGTCTACGGTTAAAAGGAGGTGAAGCTGATGCATAG
>g3722.t3 Gene=g3722 Length=448
MQTTSSHSPNPSPEIDDASSKRQATRVFKKSSANGKITVYLGKRDFVDHITHVDPIDGVV
LIDPDYMKDRKVFGHVLAAFRYGREDLDVLGLTFRKDLYLASEQIYPCLQDVNERRPLTR
LQERLIKKLGPNAYPFYFELPPHCPASVSLQPAPGDTGKPCGVDYELKAFVGDCSEDKPH
KRNSVRLAIRKIMYAPSKVGEQPSIEVSKEFMLKPNKIHLEASLDKELYHHGENISVNVH
IANNSSKTVKKIKVSVRQFADICLFSTAQYKCNVAEVEDDGCQVQPGFTLSKVFSLTPLL
ANNKDKWGLALDGQLKHEDTNLASSTLIADPSQRENLGIIVQYKVKVKLCITPLGGDLVA
ELPFILMHPKPDDLDENNLIIDQSTSNNENKVNIQSKDSSEKGIISSPQTVKDDVPNLIQ
LDGDDTHDDDIIFEDFARLRLKGGEADA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g3722.t3 | Gene3D | G3DSA:2.60.40.840 | - | 19 | 197 | 2.5E-85 |
| 12 | g3722.t3 | Gene3D | G3DSA:2.60.40.640 | - | 201 | 430 | 6.9E-83 |
| 16 | g3722.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 26 | - |
| 17 | g3722.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 18 | - |
| 15 | g3722.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 385 | 408 | - |
| 3 | g3722.t3 | PANTHER | PTHR11792 | ARRESTIN | 21 | 446 | 1.7E-193 |
| 4 | g3722.t3 | PANTHER | PTHR11792:SF17 | KURTZ ARRESTIN | 21 | 446 | 1.7E-193 |
| 8 | g3722.t3 | PRINTS | PR00309 | Arrestin signature | 43 | 65 | 1.4E-41 |
| 6 | g3722.t3 | PRINTS | PR00309 | Arrestin signature | 80 | 98 | 1.4E-41 |
| 7 | g3722.t3 | PRINTS | PR00309 | Arrestin signature | 176 | 193 | 1.4E-41 |
| 5 | g3722.t3 | PRINTS | PR00309 | Arrestin signature | 302 | 320 | 1.4E-41 |
| 1 | g3722.t3 | Pfam | PF00339 | Arrestin (or S-antigen), N-terminal domain | 38 | 194 | 3.2E-30 |
| 2 | g3722.t3 | Pfam | PF02752 | Arrestin (or S-antigen), C-terminal domain | 215 | 370 | 1.5E-32 |
| 13 | g3722.t3 | ProSitePatterns | PS00295 | Arrestins signature. | 80 | 98 | - |
| 14 | g3722.t3 | SMART | SM01017 | Arrestin_C_2 | 214 | 371 | 1.3E-34 |
| 9 | g3722.t3 | SUPERFAMILY | SSF81296 | E set domains | 25 | 196 | 2.2E-75 |
| 10 | g3722.t3 | SUPERFAMILY | SSF81296 | E set domains | 200 | 378 | 1.21E-60 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
KEGG
Orthology
- This transcript has been annotated with K04439 (beta-arrestin)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
