General information for g4037.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Pickpocket protein 28.
Parent gene
- The parent gene g4037 is located on chr_3: 29902090..29905500 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g4037 | g4037.t1 | isoform | g4037.t1 | 29902090 | 29905500 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon1 | 29902090 | 29903111 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS1 | 29902090 | 29903111 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon2 | 29903163 | 29903459 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS2 | 29903163 | 29903459 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon3 | 29903585 | 29903941 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS3 | 29903585 | 29903941 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon4 | 29903998 | 29904127 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS4 | 29903998 | 29904127 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon5 | 29904194 | 29904345 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS5 | 29904194 | 29904345 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon6 | 29904397 | 29905239 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS6 | 29904397 | 29905239 |
| chr_3 | g4037 | g4037.t1 | exon | g4037.t1.exon7 | 29905293 | 29905500 |
| chr_3 | g4037 | g4037.t1 | cds | g4037.t1.CDS7 | 29905293 | 29905500 |
| chr_3 | g4037 | g4037.t1 | TSS | g4037.t1 | NA | NA |
| chr_3 | g4037 | g4037.t1 | TTS | g4037.t1 | NA | NA |
Sequences
>g4037.t1 Gene=g4037 Length=3009
ATGTTGAAAATTATAAAAAACTTCTGTCTTAACACAAATCTCAATGGCTTTATTTACATT
GCTCAGCCTTCACGTCATAAAATTGAACGCATATTTTGGTCAATAACAATTTTTATTTCT
TTTATTCTAACTGGATTTTTGATTAAAAAATTAATTCGAGAAAGTGAAAAAAATCCAATT
GTGATTTATACTGATCAAAATGTTGTGCATGTCGAAAATATTAATTTTCCTGCTATTTCT
GTTTGCCCTGGTATAATTTTACACACACCGAAAAGATTAACTTTTGTTTATAAACATTAT
GTTGATTTAATTAAAAACAAATTTGGAGTTAATGCATATGAAGAACGAATTATGAAAATG
ATGCAAGTTGCAAGTTTAATGATGAGAGATAATTTTATGCAAAGTTATTTTGAAATGTTT
TCAATTCCAACTGATGACTTTGTTGAACAGTTGCACAAATTTGAACCATTTTTCTTTACC
ACTTATGATCTTATTCGTAACCGAACTTTGAGTTTCTTTGATGCAACTTGGTTAAGAAAT
TCAATGGCAAATTTTACTCAAACATTTTGGAAGCAAGGGTTTTGTTATACTTTTAATTTT
CCTGGAATTGACAAAATGTTTCATTTAGAGAAAATTTCAAAAGATTTCGTTTATCAAACT
TTCACTCCAGGCATTGATTCTTATAATTTACCAGCATTGAATTCTTCATTACCTTTAAAA
TCACCTTTACCTGGTGAAGGACTTGTAATCAGATATAATAAAGAATACATTTATATAGTA
CAAAATACAACAATATCAGTCGATATGAAAACTTACGATAGGATTTATCTTTTTGACATA
TATCAATTTGCTGCACCACAAACTCTTAAAAATGGACATCGATTTATTTTTCATGATAGC
TACGAAGTTGTTCCATTCAATGCTAAAAGTTTCTACTCAAATTCTGATTCAATTACAAAA
ATTTTAATTACACCAAAGATTCGTAGAGTTGATGAATCACTAAGAAAAGAGAAAGCTGAA
ATTCGAAATTGCTACATGGATAATGAAAGGAGATTGAAATTTCTAAAAGTCTACAATCGA
GTTAATTGCGAGCATGAATGTTTAGCTGAAATTACTTTATCTTCATGCAAATGCGTTCAA
TTTTTCATGGTCAGAGACAGAAAAACAAGGATTTGTGGAGCAAGAGATGAAAATTGTTAC
AGATCAATTGAAGATAATTTTGAAAATCTTAAGGATGATTGTAAATGTTATGAAAATTGC
AATAATATCAAATATGAAAGAAGAATTGCTTATATGAAAAAATCTGATCGAAACATTTTT
GAATTTTTACGGAAAACTGAAGCGAAAATCATAATTGAAATGTCATCACATGTGTTTTTA
TCAGTCAGTAAACGACAATCAACAACTGTTATCGATCTGTTGTCTTTGTCAGGAGGATTT
CTTGGACTTTTTGCAGGATTTTCAGTTCTATCAGCTGCTGAAATTGTTTATTATTTTTTA
ATGATACCGCTAATTCAATTTCGAGCTAAAAAATCAACTCGAGTAATTCCATTCAATGAA
GAATCAATGAAAGCAAAGGAAAATTCAGTCATTAAATATTTTAAGAAAATTTTGCAAGAA
TCTTCAATTCATGGTTTCAATCATATTGGAAATAGTCAGAAAAATATTTTTGAAAGGATA
ATTTGGTCATTATTGTTTCTAATTTCAATGATTTGTACTTATTTAATTGTTATGCAAGTT
TATGGAAAAACAAACATAAATTCAGTATCGATTACAATGGAAGGAAGCTTAACAAAAGTT
GAAGATATTCCATTTCCAGCAGTTACATTTCAACCTAATTACTTTGACTATAGTAAATCT
TTTGATCTTTCAAGATTGATGAGAATTTTCGTTTCTAAAGATTTTGGCACAAAAATGTTC
AACAAAATCAGCCAATTTCGAACCTTTACTGATCTTAGAAAACAAGTTTTAGCAATGATT
TGTGGTGGAGCAGTTGCTAAGATTATAAAATATGATTTTTATAATTTCTCAAAATCTACA
GCAGTTTATGATGATTTCAGAACATATATAAATGAGTCAAGACAATTTCAATGGTTTATT
AGTAAATATGCCAGGTGGTGGGAACAAAATCCATTAGAATTAGCTGAAATTATGACTAAA
AATGGAATTAATTATGTCTTCAATATGATTGAAGCATCAAAATTATTGAAATTGAAAAAA
ATCACAAAAGACTTTAATTATTCTTATGGAAAAGAAGTCAATTATCCTGTGAAAACTTCA
GCGGGACTTTCGAAAGGTGCATCAATTGGATTTCAAAGTCTAAAATCAGCTATGCCTTGC
ACAAAAGCAAGTTTTGTAATCCATTCACCTTATGAATTTCCAACTGCAAATGAAGTCGTA
GAAATTGATCCAAATTTAGTTTATAGAATTTTAATAACACCATCAATTATCAAAACTGAT
GACGATTTAAGAACATTGCCAGTTTCTTTTAGAAAATGTTATTTTGAAGATGAAAGAGAT
TTGAAATTTTTCAAGATTTATACACAACGAAATTGCGAATTTGAATGTTTGTCTGAAGCA
ATAAATAAGAAATGCAATTGTGTTCCATTTTATTTTATAAGAAGTCCAAAATGGCAAGTT
TGTGAATATCGAAGAATGAAATTTTGTGTTGAAAAGTTTCTTTTTGAAAGATCAATTGGA
AATGCAACTGAAAAATTTGATTGTGACTGTTTACCTGGATGCAATTCAATTACTTATTCA
TATGAAATTTTCACAACTCAAGCTGTTCATGAACATAATGTAGCAGAGTTTTATGCAATA
CATTTTGGATTTGAAGATCCAGAGCATTATGCATTGATACGCTATCAAGAGTTCAAACTT
GTCGATTTCCTTTCATACGTTGGTGGAATTTTAGGACTTTTCGCTGGAATTTCTGTGATA
TCGTTTGTTGAAATTGCATATTTTATTACATTTAGATTGATCACTGATTTGAAAAGACAT
TTTTTATGA
>g4037.t1 Gene=g4037 Length=1002
MLKIIKNFCLNTNLNGFIYIAQPSRHKIERIFWSITIFISFILTGFLIKKLIRESEKNPI
VIYTDQNVVHVENINFPAISVCPGIILHTPKRLTFVYKHYVDLIKNKFGVNAYEERIMKM
MQVASLMMRDNFMQSYFEMFSIPTDDFVEQLHKFEPFFFTTYDLIRNRTLSFFDATWLRN
SMANFTQTFWKQGFCYTFNFPGIDKMFHLEKISKDFVYQTFTPGIDSYNLPALNSSLPLK
SPLPGEGLVIRYNKEYIYIVQNTTISVDMKTYDRIYLFDIYQFAAPQTLKNGHRFIFHDS
YEVVPFNAKSFYSNSDSITKILITPKIRRVDESLRKEKAEIRNCYMDNERRLKFLKVYNR
VNCEHECLAEITLSSCKCVQFFMVRDRKTRICGARDENCYRSIEDNFENLKDDCKCYENC
NNIKYERRIAYMKKSDRNIFEFLRKTEAKIIIEMSSHVFLSVSKRQSTTVIDLLSLSGGF
LGLFAGFSVLSAAEIVYYFLMIPLIQFRAKKSTRVIPFNEESMKAKENSVIKYFKKILQE
SSIHGFNHIGNSQKNIFERIIWSLLFLISMICTYLIVMQVYGKTNINSVSITMEGSLTKV
EDIPFPAVTFQPNYFDYSKSFDLSRLMRIFVSKDFGTKMFNKISQFRTFTDLRKQVLAMI
CGGAVAKIIKYDFYNFSKSTAVYDDFRTYINESRQFQWFISKYARWWEQNPLELAEIMTK
NGINYVFNMIEASKLLKLKKITKDFNYSYGKEVNYPVKTSAGLSKGASIGFQSLKSAMPC
TKASFVIHSPYEFPTANEVVEIDPNLVYRILITPSIIKTDDDLRTLPVSFRKCYFEDERD
LKFFKIYTQRNCEFECLSEAINKKCNCVPFYFIRSPKWQVCEYRRMKFCVEKFLFERSIG
NATEKFDCDCLPGCNSITYSYEIFTTQAVHEHNVAEFYAIHFGFEDPEHYALIRYQEFKL
VDFLSYVGGILGLFAGISVISFVEIAYFITFRLITDLKRHFL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g4037.t1 | Gene3D | G3DSA:1.10.287.770 | - | 559 | 985 | 4.4E-31 |
| 11 | g4037.t1 | Gene3D | G3DSA:2.60.470.10 | - | 589 | 956 | 4.4E-31 |
| 12 | g4037.t1 | Gene3D | G3DSA:1.10.3590.10 | - | 613 | 782 | 4.4E-31 |
| 13 | g4037.t1 | Gene3D | G3DSA:1.10.287.820 | - | 825 | 914 | 4.4E-31 |
| 4 | g4037.t1 | PANTHER | PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | 3 | 515 | 7.7E-97 |
| 6 | g4037.t1 | PANTHER | PTHR11690:SF237 | NACH, ISOFORM E-RELATED | 3 | 515 | 7.7E-97 |
| 3 | g4037.t1 | PANTHER | PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | 510 | 998 | 7.7E-97 |
| 5 | g4037.t1 | PANTHER | PTHR11690:SF237 | NACH, ISOFORM E-RELATED | 510 | 998 | 7.7E-97 |
| 2 | g4037.t1 | Pfam | PF00858 | Amiloride-sensitive sodium channel | 8 | 498 | 2.4E-57 |
| 1 | g4037.t1 | Pfam | PF00858 | Amiloride-sensitive sodium channel | 539 | 988 | 6.7E-56 |
| 15 | g4037.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 30 | - |
| 22 | g4037.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 31 | 48 | - |
| 18 | g4037.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 49 | 472 | - |
| 23 | g4037.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 473 | 500 | - |
| 17 | g4037.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 501 | 559 | - |
| 20 | g4037.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 560 | 581 | - |
| 19 | g4037.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 582 | 962 | - |
| 21 | g4037.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 963 | 989 | - |
| 16 | g4037.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 990 | 1002 | - |
| 9 | g4037.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 31 | 48 | - |
| 10 | g4037.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 483 | 505 | - |
| 8 | g4037.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 560 | 582 | - |
| 7 | g4037.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 967 | 989 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005272 | sodium channel activity | MF |
| GO:0006814 | sodium ion transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed