General information for g4122.t14
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldehyde dehydrogenase, mitochondrial.
Parent gene
- The parent gene g4122 is located on chr_3: 30744881..30746107 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g4122 | g4122.t14 | TTS | g4122.t14 | 30743782 | 30743782 |
| chr_3 | g4122 | g4122.t14 | isoform | g4122.t14 | 30743874 | 30745693 |
| chr_3 | g4122 | g4122.t14 | exon | g4122.t14.exon1 | 30743874 | 30744554 |
| chr_3 | g4122 | g4122.t14 | cds | g4122.t14.CDS1 | 30744431 | 30744554 |
| chr_3 | g4122 | g4122.t14 | exon | g4122.t14.exon2 | 30744722 | 30745144 |
| chr_3 | g4122 | g4122.t14 | cds | g4122.t14.CDS2 | 30744722 | 30745144 |
| chr_3 | g4122 | g4122.t14 | exon | g4122.t14.exon3 | 30745203 | 30745319 |
| chr_3 | g4122 | g4122.t14 | cds | g4122.t14.CDS3 | 30745203 | 30745319 |
| chr_3 | g4122 | g4122.t14 | exon | g4122.t14.exon4 | 30745375 | 30745580 |
| chr_3 | g4122 | g4122.t14 | cds | g4122.t14.CDS4 | 30745375 | 30745580 |
| chr_3 | g4122 | g4122.t14 | exon | g4122.t14.exon5 | 30745637 | 30745693 |
| chr_3 | g4122 | g4122.t14 | cds | g4122.t14.CDS5 | 30745637 | 30745693 |
| chr_3 | g4122 | g4122.t14 | TSS | g4122.t14 | 30745933 | 30745933 |
Sequences
>g4122.t14 Gene=g4122 Length=1484
ATGGAAACTCCAAAAAATCCTAATCCAAATCCAGATCAAGAAATTCAGTTCACGAAGCTT
TTTATCAACAATGAATTCGTTGATTCAATCAGTAAAAAGACTTTTGCTACAATTAACCCA
GCAAATGGCAAAAAAATCGCTGACATCGCTGAAGCTGATAAGGCTGATGTCGATTTAGCA
GTTAAAGCTGCACAAAAAGCATTCGAACGTGGCTCTGAATGGCGAAATTTAGATGCTTCA
GCTCGTGGAAGATTACTTTATCGTTTAGCGGACCTAATTGACCGTGATTCAGCTATTCTC
TCCAATTTGGAAACATTAGACAATGGAAAACCTTATGAAGATGCATGTCTGGATGTTTTG
TTTAGTGGTGAATTTTTACGTTATTATGCGGGATTATGTGACAAAATTCATGGCAGAACT
GTTCCAAGTGATGGCAATCTTTTTAGTTATGTTCGCAAAGAACCAATTGGTGTAGTAGGC
CAAATTATACCTTGGAATTATCCTCTTATGATGGTAAGCTGGAAATGGGCACCGGCTTTA
GCTGCTGGATGCACAATAGTACTTAAACCAGCAGAACAAACTCCCCTTTCGGCTTTATAT
GTCGCAAATCTCGCGAAAGAAGCGGGTTTTCCTGCTGGCGTAGTTAACGTAATTACTGGC
TATGGGCCAACTGTTGGTGCCGCTATTGCATCACATCCTGATATTCGCAAGGTTGCATTT
ACAGGCTCAACTGAAGTTGGAAAATTAATTATGGAAGCTGCTGCAAAATCAAATTTGAAG
AAAGTTTCATTAGAGTTGGGTAATTTCAATTTACAGTTGATGAAGCAGTTGATATTGCTC
ATAATGCAATATTTGCAAACCATGGTCAAAACTGTTGTGCTGGTTCTCGTACATTCGTTC
ATGAGAAAATTTATGATGAATTTGTAGAAAAAGCAGCTGAAATGGCCAAAAATAGAAAAC
TTGGTTCTCCTTTCGAAATTGGTGTTCAACAGGGACCACAAGTTGATGATCAGATGTTTA
AAAAAGTTCTCACTTACATTGATTATGGCAAAGAAGATGGTGCAAAATTGGAAGCCGGTG
GAAAGAGATGGGGCAATGAAGGTTTCTATATTGAACCAACTGTTTTCTCAAATGTTACTG
ACGATATGCGCATTGCACAAGATGAAATTTTCGGACCTGTTCAATCGATTCTCAAGTTCA
AGACAATTGATGAAGTTATTGAGCGTGCTAATAATACAACTTATGGATTAGCTGCTGGAG
TTCTAACAAATGACATTAATACAGCTTTGACATTTGCAAATGCAGTCGAAGCTGGATCAG
TTTGGGTTAATTGTTACGATGCTGTTACACCACAAATGCCTTTTGGAGGATATAAGCAAA
GCGGAATTGGAAGAGAATTGGGTGCAGAAGGAATCGAATCTTATCTTGAAACAAAAGCAG
TTTCAATTAAATTACCATCATTTAAAGTACCATCAAAAATCTAA
>g4122.t14 Gene=g4122 Length=308
METPKNPNPNPDQEIQFTKLFINNEFVDSISKKTFATINPANGKKIADIAEADKADVDLA
VKAAQKAFERGSEWRNLDASARGRLLYRLADLIDRDSAILSNLETLDNGKPYEDACLDVL
FSGEFLRYYAGLCDKIHGRTVPSDGNLFSYVRKEPIGVVGQIIPWNYPLMMVSWKWAPAL
AAGCTIVLKPAEQTPLSALYVANLAKEAGFPAGVVNVITGYGPTVGAAIASHPDIRKVAF
TGSTEVGKLIMEAAAKSNLKKVSLELGNFNLQLMKQLILLIMQYLQTMVKTVVLVLVHSF
MRKFMMNL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g4122.t14 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 1 | 292 | 1.3E-119 |
| 2 | g4122.t14 | PANTHER | PTHR11699:SF269 | ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN | 11 | 268 | 1.4E-136 |
| 3 | g4122.t14 | PANTHER | PTHR11699 | ALDEHYDE DEHYDROGENASE-RELATED | 11 | 268 | 1.4E-136 |
| 1 | g4122.t14 | Pfam | PF00171 | Aldehyde dehydrogenase family | 27 | 268 | 1.3E-90 |
| 8 | g4122.t14 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 276 | - |
| 9 | g4122.t14 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 277 | 297 | - |
| 7 | g4122.t14 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 298 | 308 | - |
| 5 | g4122.t14 | SUPERFAMILY | SSF53720 | ALDH-like | 13 | 270 | 4.06E-93 |
| 4 | g4122.t14 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 278 | 300 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
