General information for g4122.t15
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Retinal dehydrogenase 1.
Parent gene
- The parent gene g4122 is located on chr_3: 30744881..30746107 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g4122 | g4122.t15 | TTS | g4122.t15 | 30743782 | 30743782 |
| chr_3 | g4122 | g4122.t15 | isoform | g4122.t15 | 30743874 | 30745693 |
| chr_3 | g4122 | g4122.t15 | exon | g4122.t15.exon1 | 30743874 | 30744541 |
| chr_3 | g4122 | g4122.t15 | cds | g4122.t15.CDS1 | 30743874 | 30744541 |
| chr_3 | g4122 | g4122.t15 | exon | g4122.t15.exon2 | 30744597 | 30744635 |
| chr_3 | g4122 | g4122.t15 | cds | g4122.t15.CDS2 | 30744597 | 30744635 |
| chr_3 | g4122 | g4122.t15 | exon | g4122.t15.exon3 | 30744726 | 30745144 |
| chr_3 | g4122 | g4122.t15 | cds | g4122.t15.CDS3 | 30744726 | 30745144 |
| chr_3 | g4122 | g4122.t15 | exon | g4122.t15.exon4 | 30745203 | 30745314 |
| chr_3 | g4122 | g4122.t15 | cds | g4122.t15.CDS4 | 30745203 | 30745314 |
| chr_3 | g4122 | g4122.t15 | exon | g4122.t15.exon5 | 30745375 | 30745580 |
| chr_3 | g4122 | g4122.t15 | cds | g4122.t15.CDS5 | 30745375 | 30745405 |
| chr_3 | g4122 | g4122.t15 | exon | g4122.t15.exon6 | 30745637 | 30745693 |
| chr_3 | g4122 | g4122.t15 | TSS | g4122.t15 | 30745933 | 30745933 |
Sequences
>g4122.t15 Gene=g4122 Length=1501
ATGGAAACTCCAAAAAATCCTAATCCAAATCCAGATCAAGAAATTCAGTTCACGAAGCTT
TTTATCAACAATGAATTCGTTGATTCAATCAGTAAAAAGACTTTTGCTACAATTAACCCA
GCAAATGGCAAAAAAATCGCTGACATCGCTGAAGCTGATAAGGCTGATGTCGATTTAGCA
GTTAAAGCTGCACAAAAAGCATTCGAACGTGGCTCTGAATGGCGAAATTTAGATGCTTCA
GCTCGTGGAAGATTACTTTATCGCGGACCTAATTGACCGTGATTCAGCTATTCTCTCCAA
TTTGGAAACATTAGACAATGGAAAACCTTATGAAGATGCATGTCTGGATGTTTTGTTTAG
TGGTGAATTTTTACGTTATTATGCGGGATTATGTGACAAAATTCATGGCAGAACTGTTCC
AAGTGATGGCAATCTTTTTAGTTATGTTCGCAAAGAACCAATTGGTGTAGTAGGCCAAAT
TATACCTTGGAATTATCCTCTTATGATGGTAAGCTGGAAATGGGCACCGGCTTTAGCTGC
TGGATGCACAATAGTACTTAAACCAGCAGAACAAACTCCCCTTTCGGCTTTATATGTCGC
AAATCTCGCGAAAGAAGCGGGTTTTCCTGCTGGCGTAGTTAACGTAATTACTGGCTATGG
GCCAACTGTTGGTGCCGCTATTGCATCACATCCTGATATTCGCAAGGTTGCATTTACAGG
CTCAACTGAAGTTGGAAAATTAATTATGGAAGCTGCTGCAAAATCAAATTTGAAGAAAGT
TTCATTAGAGTTGGGTGGCAAGAGTCCTCTCGTCATCTTTGATGACGTAAACATTGATGA
AGCAGTTGATATTGCTCATAATGCAATATTTGCAAACCATGGTCAAAACTGTTGTGCTGG
TTCTCGTACATTCGTTCATGAGAAAATTTATGATGAATTTGTAGAAAAAGCAGCTGAAAT
GGCCAAAAATAGAAAACTTGGTTCTCCTTTCGAAATTGGTGTTCAACAGGGACCACAAGT
TGATGATCAGATGTTTAAAAAAGTTCTCACTTACATTGATTATGGCAAAGAAGATGGTGC
AAAATTGGAAGCCGGTGGAAAGAGATGGGGCAATGAAGGTTTCTATATTGAACCAACTGT
TTTCTCAAATGTTACTGACGATATGCGCATTGCACAAGATGAAATTTTCGGACCTGTTCA
ATCGATTCTCAAGTTCAAGACAATTGATGAAGTTATTGAGCGTGCTAATAATACAACTTA
TGGATTAGCTGCTGGAGTTCTAACAAATGACATTAATACAGCTTTGACATTTGCAAATGC
AGTCGAAGCTGGATCAGTTTGGGTTAATTGTTACGATGCTGTTACACCACAAATGCCTTT
TGGAGGATATAAGCAAAGCGGAATTGGAAGAGAATTGGGTGCAGAAGGAATCGAATCTTA
TCTTGAAACAAAAGCAGTTTCAATTAAATTACCATCATTTAAAGTACCATCAAAAATCTA
A
>g4122.t15 Gene=g4122 Length=422
MLQLVEDYFIADLIDRDSAILSNLETLDNGKPYEDACLDVLFSGEFLRYYAGLCDKIHGR
TVPSDGNLFSYVRKEPIGVVGQIIPWNYPLMMVSWKWAPALAAGCTIVLKPAEQTPLSAL
YVANLAKEAGFPAGVVNVITGYGPTVGAAIASHPDIRKVAFTGSTEVGKLIMEAAAKSNL
KKVSLELGGKSPLVIFDDVNIDEAVDIAHNAIFANHGQNCCAGSRTFVHEKIYDEFVEKA
AEMAKNRKLGSPFEIGVQQGPQVDDQMFKKVLTYIDYGKEDGAKLEAGGKRWGNEGFYIE
PTVFSNVTDDMRIAQDEIFGPVQSILKFKTIDEVIERANNTTYGLAAGVLTNDINTALTF
ANAVEAGSVWVNCYDAVTPQMPFGGYKQSGIGRELGAEGIESYLETKAVSIKLPSFKVPS
KI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g4122.t15 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 10 | 409 | 3.9E-176 |
| 8 | g4122.t15 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 192 | 381 | 3.9E-176 |
| 2 | g4122.t15 | PANTHER | PTHR11699:SF269 | ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN | 10 | 415 | 4.5E-230 |
| 3 | g4122.t15 | PANTHER | PTHR11699 | ALDEHYDE DEHYDROGENASE-RELATED | 10 | 415 | 4.5E-230 |
| 1 | g4122.t15 | Pfam | PF00171 | Aldehyde dehydrogenase family | 10 | 409 | 3.7E-163 |
| 6 | g4122.t15 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 185 | 192 | - |
| 5 | g4122.t15 | ProSitePatterns | PS00070 | Aldehyde dehydrogenases cysteine active site. | 213 | 224 | - |
| 4 | g4122.t15 | SUPERFAMILY | SSF53720 | ALDH-like | 10 | 413 | 1.02E-157 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
